hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05227.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KBTBD7 | Kelch repeat and BTB domain-containing protein 7 | 5 | UniProt NCBI |
| KBTBD8 | Kelch repeat and BTB domain-containing protein 8 (T-cell activation kelch repeat protein) (TA-KRP) | 5 | UniProt NCBI |
| CDX1 | Homeobox protein CDX-1 (Caudal-type homeobox protein 1) | 5 | UniProt NCBI |
| GREM2 | Gremlin-2 (Cysteine knot superfamily 1, BMP antagonist 2) (DAN domain family member 3) (Protein related to DAN and cerberus) | 5 | UniProt NCBI |
| TEFM | Transcription elongation factor, mitochondrial | 5 | UniProt NCBI |
| KBTBD6 | Kelch repeat and BTB domain-containing protein 6 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8951664 | 0.012792006299 | 0.5 | KBTBD6 KBTBD7 KBTBD8 | Neddylation |
| GO:0031463 | 0.017471616814 | 0.5 | KBTBD6 KBTBD7 KBTBD8 | Cul3-RING ubiquitin ligase complex |
| REAC:R-HSA-983168 | 0.0250300575692 | 0.5 | KBTBD6 KBTBD7 KBTBD8 | Antigen processing: Ubiquitination & Proteasome degradation |
| REAC:R-HSA-983169 | 0.0458629512724 | 0.5 | KBTBD6 KBTBD7 KBTBD8 | Class I MHC mediated antigen processing & presentation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| KBTBD7 | KBTBD6 | 1.0 | 0.246 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM boldt_WMM |
| KBTBD7 | TEFM | 0.999 | 0.138 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 |
| CDX1 | KBTBD6 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| KBTBD7 | CDX1 | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| KBTBD7 | GREM2 | 0.992 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| GREM2 | KBTBD6 | 0.984 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| KBTBD7 | KBTBD8 | 0.975 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| TEFM | KBTBD6 | 0.459 | 0.084 | hein_WMM bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| KBTBD8 | TEFM | 0.237 | 0.05 | bioplex_WMM bioplex3_WMM WMM_only |
| KBTBD8 | KBTBD6 | 0.11 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes