hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05231.1
Complex Portal: CPX-21428
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NTPCR | Cancer-related nucleoside-triphosphatase (NTPase) (EC 3.6.1.15) (Nucleoside triphosphate phosphohydrolase) | 5 | UniProt NCBI |
| SCO2 | Protein SCO2 homolog, mitochondrial | 5 | UniProt NCBI |
| ZFYVE19 | Abscission/NoCut checkpoint regulator (ANCHR) (MLL partner containing FYVE domain) (Zinc finger FYVE domain-containing protein 19) | 5 | UniProt NCBI |
| VPS4A | Vacuolar protein sorting-associated protein 4A (EC 3.6.4.6) (Protein SKD2) (VPS4-1) (hVPS4) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0044878 | 0.0168521501606 | 0.5 | ZFYVE19 VPS4A | mitotic cytokinesis checkpoint signaling |
| GO:0009838 | 0.042122686785 | 0.5 | ZFYVE19 VPS4A | abscission |
| GO:0032466 | 0.042122686785 | 0.5 | ZFYVE19 VPS4A | negative regulation of cytokinesis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SCO2 | VPS4A | 0.985 | 0.018 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt boldt_WMM | |
| ZFYVE19 | VPS4A | 0.982 | 0.174 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| NTPCR | VPS4A | 0.98 | 0.066 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| SCO2 | NTPCR | 0.106 | 0.108 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| SCO2 | ZFYVE19 | 0.011 | 0.06 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes