hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_05234.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CREB3L1 | Cyclic AMP-responsive element-binding protein 3-like protein 1 (cAMP-responsive element-binding protein 3-like protein 1) (Old astrocyte specifically-induced substance) (OASIS) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 1] | 5 | UniProt NCBI |
| CREB3L2 | Cyclic AMP-responsive element-binding protein 3-like protein 2 (cAMP-responsive element-binding protein 3-like protein 2) (BBF2 human homolog on chromosome 7) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 2] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8874211 | 3.58839967947e-05 | 1.0 | CREB3L2 CREB3L1 | CREB3 factors activate genes |
| WP:WP5272 | 7.2783930122e-05 | 1.0 | CREB3L2 CREB3L1 | LDL influence on CD14 and TLR4 |
| KEGG:04962 | 0.000126804361689 | 1.0 | CREB3L2 CREB3L1 | Vasopressin-regulated water reabsorption |
| KEGG:05030 | 0.000133307149468 | 1.0 | CREB3L2 CREB3L1 | Cocaine addiction |
| KEGG:04927 | 0.000139972506942 | 1.0 | CREB3L2 CREB3L1 | Cortisol synthesis and secretion |
| WP:WP4756 | 0.000238782367243 | 1.0 | CREB3L2 CREB3L1 | Renin angiotensin aldosterone system RAAS |
| KEGG:05031 | 0.00025946123238 | 1.0 | CREB3L2 CREB3L1 | Amphetamine addiction |
| KEGG:04918 | 0.000287748359218 | 1.0 | CREB3L2 CREB3L1 | Thyroid hormone synthesis |
| WP:WP5085 | 0.000331996874241 | 1.0 | CREB3L2 CREB3L1 | Vasopressin regulated water reabsorption |
| KEGG:04911 | 0.000338144964505 | 1.0 | CREB3L2 CREB3L1 | Insulin secretion |
| KEGG:04925 | 0.000439100744773 | 1.0 | CREB3L2 CREB3L1 | Aldosterone synthesis and secretion |
| KEGG:04211 | 0.000526725810094 | 1.0 | CREB3L2 CREB3L1 | Longevity regulating pathway |
| KEGG:04916 | 0.000553224670293 | 1.0 | CREB3L2 CREB3L1 | Melanogenesis |
| KEGG:04928 | 0.000553224670293 | 1.0 | CREB3L2 CREB3L1 | Parathyroid hormone synthesis, secretion and action |
| KEGG:04725 | 0.000636622923558 | 1.0 | CREB3L2 CREB3L1 | Cholinergic synapse |
| KEGG:05215 | 0.000651091626366 | 1.0 | CREB3L2 CREB3L1 | Prostate cancer |
| KEGG:04922 | 0.000680516741066 | 1.0 | CREB3L2 CREB3L1 | Glucagon signaling pathway |
| KEGG:04915 | 0.000680516741066 | 1.0 | CREB3L2 CREB3L1 | Estrogen signaling pathway |
| KEGG:04668 | 0.000725873685824 | 1.0 | CREB3L2 CREB3L1 | TNF signaling pathway |
| KEGG:04931 | 0.000772693757832 | 1.0 | CREB3L2 CREB3L1 | Insulin resistance |
| KEGG:04935 | 0.000804719987643 | 1.0 | CREB3L2 CREB3L1 | Growth hormone synthesis, secretion and action |
| KEGG:04926 | 0.000939327694667 | 1.0 | CREB3L2 CREB3L1 | Relaxin signaling pathway |
| KEGG:04728 | 0.00095688522167 | 1.0 | CREB3L2 CREB3L1 | Dopaminergic synapse |
| KEGG:04152 | 0.00102874102663 | 1.0 | CREB3L2 CREB3L1 | AMPK signaling pathway |
| KEGG:04261 | 0.0011414018249 | 1.0 | CREB3L2 CREB3L1 | Adrenergic signaling in cardiomyocytes |
| KEGG:04934 | 0.00125991513217 | 1.0 | CREB3L2 CREB3L1 | Cushing syndrome |
| KEGG:04022 | 0.00125991513217 | 1.0 | CREB3L2 CREB3L1 | cGMP-PKG signaling pathway |
| WP:WP4321 | 0.00174298358976 | 1.0 | CREB3L2 CREB3L1 | Thermogenesis |
| KEGG:05161 | 0.00176843313648 | 1.0 | CREB3L2 CREB3L1 | Hepatitis B |
| KEGG:05034 | 0.00179249345126 | 1.0 | CREB3L2 CREB3L1 | Alcoholism |
| KEGG:04024 | 0.00201635192055 | 1.0 | CREB3L2 CREB3L1 | cAMP signaling pathway |
| KEGG:05207 | 0.00214640767613 | 1.0 | CREB3L2 CREB3L1 | Chemical carcinogenesis - receptor activation |
| KEGG:05203 | 0.00279701159341 | 1.0 | CREB3L2 CREB3L1 | Viral carcinogenesis |
| KEGG:05163 | 0.00298087791786 | 1.0 | CREB3L2 CREB3L1 | Human cytomegalovirus infection |
| KEGG:05166 | 0.00317059675131 | 1.0 | CREB3L2 CREB3L1 | Human T-cell leukemia virus 1 infection |
| KEGG:04714 | 0.00339933231144 | 1.0 | CREB3L2 CREB3L1 | Thermogenesis |
| WP:WP4666 | 0.00396523446209 | 1.0 | CREB3L2 CREB3L1 | Hepatitis B infection |
| KEGG:05020 | 0.00485920816781 | 1.0 | CREB3L2 CREB3L1 | Prion disease |
| KEGG:05016 | 0.00594761227231 | 1.0 | CREB3L2 CREB3L1 | Huntington disease |
| REAC:R-HSA-381119 | 0.00595674346792 | 1.0 | CREB3L2 CREB3L1 | Unfolded Protein Response (UPR) |
| KEGG:04151 | 0.00662552789826 | 1.0 | CREB3L2 CREB3L1 | PI3K-Akt signaling pathway |
| KEGG:05165 | 0.00700203931066 | 1.0 | CREB3L2 CREB3L1 | Human papillomavirus infection |
| WP:WP3932 | 0.0130364105952 | 1.0 | CREB3L2 CREB3L1 | Focal adhesion PI3K Akt mTOR signaling pathway |
| GO:0035497 | 0.0131096201623 | 1.0 | CREB3L2 CREB3L1 | cAMP response element binding |
| WP:WP4172 | 0.015571930313 | 1.0 | CREB3L2 CREB3L1 | PI3K Akt signaling pathway |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CREB3L1 | CREB3L2 | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| CREB3L1 | huMAP3_05234.1 huMAP3_09384.1 huMAP3_09500.1 huMAP3_11532.1 huMAP3_12702.1 huMAP3_14135.1 huMAP3_14456.1 |
| CREB3L2 | huMAP3_05234.1 huMAP3_07546.1 huMAP3_09377.1 huMAP3_09384.1 huMAP3_11731.1 |