hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_05235.1
Complex Portal: CPX-22625
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PTEN | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Inositol polyphosphate 3-phosphatase) (EC 3.1.3.-) (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog) | 5 | UniProt NCBI |
| RPUSD1 | RNA pseudouridylate synthase domain-containing protein 1 (Ribosomal large subunit pseudouridine synthase C-like protein) | 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5674404 | 0.0249718442457 | 0.5 | PTEN | PTEN Loss of Function in Cancer |
| WP:WP4186 | 0.0373151717536 | 0.5 | PTEN | Somatroph axis GH and its relationship to dietary restriction and aging |
| HP:0500009 | 0.0499436884913 | 0.5 | PTEN | Dysplastic gangliocytoma of the cerebellum |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RPUSD1 | PTEN | 0.986 | 0.064 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| PTEN | huMAP3_05235.1 huMAP3_12159.1 huMAP3_12246.1 |
| RPUSD1 | huMAP3_00067.1 huMAP3_05235.1 huMAP3_12159.1 |