hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_05240.1
Complex Portal: CPX-22902
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ACTC1 | Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form] | 5 | UniProt NCBI |
| CAP2 | Adenylyl cyclase-associated protein 2 (CAP 2) | 5 | UniProt NCBI |
| UBC | Polyubiquitin-C [Cleaved into: Ubiquitin] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0001727 | 0.0208637442425 | 0.666666666667 | ACTC1 CAP2 | Thromboembolic stroke |
| HP:0012764 | 0.023094623718 | 0.666666666667 | ACTC1 CAP2 | Orthopnea |
| HP:0100578 | 0.0287391839378 | 0.666666666667 | ACTC1 CAP2 | Lipoatrophy |
| HP:0025169 | 0.0295957156854 | 0.666666666667 | ACTC1 CAP2 | Left ventricular systolic dysfunction |
| HP:0001907 | 0.037868427304 | 0.666666666667 | ACTC1 CAP2 | Thromboembolism |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CAP2 | UBC | 0.993 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ACTC1 | CAP2 | 0.991 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ACTC1 | UBC | 0.023 | bioplex3_WMM WMM_only boldt_WMM |
Related Complexes