hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05241.1
Complex Portal: CPX-15813
Confidence: Extremely High  
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RIT1 | GTP-binding protein Rit1 (EC 3.6.5.2) (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1) | 5 | UniProt   NCBI |
| TMEM182 | Transmembrane protein 182 | 5 | UniProt   NCBI |
| RIT2 | GTP-binding protein Rit2 (EC 3.6.5.2) (Ras-like protein expressed in neurons) (Ras-like without CAAX protein 2) | 5 | UniProt   NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
|   REAC:R-HSA-187706 | 2.04544380615e-05 | 0.666666666667 | RIT1 RIT2 | Signalling to p38 via RIT and RIN |
|   REAC:R-HSA-187687 | 0.00221357222266 | 0.666666666667 | RIT1 RIT2 | Signalling to ERKs |
|   REAC:R-HSA-187037 | 0.0316091445651 | 0.666666666667 | RIT1 RIT2 | Signaling by NTRK1 (TRKA) |
|   REAC:R-HSA-166520 | 0.0436932800731 | 0.666666666667 | RIT1 RIT2 | Signaling by NTRKs |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
|  RIT1 |  RIT2 | 0.989 |            |          | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
|  RIT1 |  TMEM182 | 0.958 |            |          | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
Related Complexes
| Genename | Complexes |
|---|---|
| RIT1 | huMAP3_05241.1 huMAP3_10319.1 huMAP3_11695.1 huMAP3_13790.1 |
| TMEM182 | huMAP3_05241.1 huMAP3_10319.1 huMAP3_12467.1 |
| RIT2 | huMAP3_05241.1 huMAP3_10319.1 huMAP3_11695.1 huMAP3_13790.1 |