hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05268.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PICK1 | PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein) | 5 | UniProt NCBI |
| ICA1L | Islet cell autoantigen 1-like protein (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 14 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 15 protein) | 5 | UniProt NCBI |
| PRXL2C | Peroxiredoxin-like 2C (AhpC/TSA antioxidant enzyme domain-containing protein 1) (Thioredoxin-like protein AAED1) | 3 | UniProt NCBI |
| JAM2 | Junctional adhesion molecule B (JAM-B) (Junctional adhesion molecule 2) (JAM-2) (Vascular endothelial junction-associated molecule) (VE-JAM) (CD antigen CD322) | 5 | UniProt NCBI |
| ICA1 | Islet cell autoantigen 1 (69 kDa islet cell autoantigen) (ICA69) (Islet cell autoantigen p69) (ICAp69) (p69) | 5 | UniProt NCBI |
| NELFA | Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0140090 | 0.0210651876021 | 0.333333333333 | ICA1 PICK1 | membrane curvature sensor activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ICA1 | PICK1 | 0.999 | 0.166 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| PICK1 | PRXL2C | 0.998 | 0.116 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| PICK1 | ICA1L | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| NELFA | PICK1 | 0.974 | 0.166 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| ICA1 | NELFA | 0.97 | 0.084 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| PICK1 | JAM2 | 0.953 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| ICA1L | PRXL2C | 0.906 | bioplex_WMM bioplex3_WMM WMM_only | |
| ICA1 | ICA1L | 0.902 | bioplex_WMM bioplex3_WMM WMM_only | |
| ICA1 | PRXL2C | 0.902 | 0.06 | bioplex_WMM bioplex3_WMM WMM_only |
| ICA1L | JAM2 | 0.415 | bioplex3_WMM WMM_only | |
| ICA1 | JAM2 | 0.415 | bioplex3_WMM WMM_only | |
| PRXL2C | JAM2 | 0.415 | bioplex3_WMM WMM_only |
Related Complexes