hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05278.1
Complex Portal: CPX-23440
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GAB2 | GRB2-associated-binding protein 2 (GRB2-associated binder 2) (Growth factor receptor bound protein 2-associated protein 2) (pp100) | 5 | UniProt NCBI |
| GRAP2 | GRB2-related adapter protein 2 (Adapter protein GRID) (GRB-2-like protein) (GRB2L) (GRBLG) (GRBX) (Grf40 adapter protein) (Grf-40) (Growth factor receptor-binding protein) (Hematopoietic cell-associated adapter protein GrpL) (P38) (Protein GADS) (SH3-SH2-SH3 adapter Mona) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9680350 | 0.000645911942305 | 1.0 | GRAP2 GAB2 | Signaling by CSF1 (M-CSF) in myeloid cells |
| WP:WP69 | 0.000778915743411 | 1.0 | GRAP2 GAB2 | T cell receptor signaling pathway |
| REAC:R-HSA-9607240 | 0.000847545829056 | 1.0 | GRAP2 GAB2 | FLT3 Signaling |
| REAC:R-HSA-1433557 | 0.00107651990384 | 1.0 | GRAP2 GAB2 | Signaling by SCF-KIT |
| REAC:R-HSA-2454202 | 0.0104319904967 | 1.0 | GRAP2 GAB2 | Fc epsilon receptor (FCERI) signaling |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| GAB2 | GRAP2 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes