hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05308.1
Complex Portal: CPX-19956
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RAF1 | RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1) | 5 | UniProt NCBI |
| WDR62 | WD repeat-containing protein 62 | 5 | UniProt NCBI |
| ARAF | Serine/threonine-protein kinase A-Raf (EC 2.7.11.1) (Proto-oncogene A-Raf) (Proto-oncogene A-Raf-1) (Proto-oncogene Pks) | 5 | UniProt NCBI |
| AFAP1L1 | Actin filament-associated protein 1-like 1 (AFAP1-like protein 1) | 5 | UniProt NCBI |
| PTOV1 | Prostate tumor-overexpressed gene 1 protein (PTOV-1) (Activator interaction domain-containing protein 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5923 | 0.0249718442456 | 0.25 | RAF1 | RAF1-BRAF complex, RAS stimulated |
| CORUM:5919 | 0.049938562206 | 0.25 | RAF1 | BRAF-RAF1-14-3-3 complex |
| CORUM:5922 | 0.049938562206 | 0.25 | RAF1 | RAF1-RAS complex, EGF induced |
| CORUM:5924 | 0.049938562206 | 0.25 | RAF1 | RAF1-CNK1 complex, RAS stimulated |
| CORUM:5928 | 0.049938562206 | 0.25 | RAF1 | CNK1-SRC-RAF1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ARAF | RAF1 | 0.998 | 0.176 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| PTOV1 | RAF1 | 0.987 | 0.152222222222 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| PTOV1 | WDR62 | 0.985 | 0.108 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| PTOV1 | ARAF | 0.961 | 0.062 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| AFAP1L1 | PTOV1 | 0.953 | 0.068 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ARAF | WDR62 | 0.657 | 0.062 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only | |
| RAF1 | WDR62 | 0.503 | 0.074 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| AFAP1L1 | RAF1 | 0.015 | 0.154222222222 | bioplex3_WMM WMM_only |
Related Complexes