hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05316.1
Complex Portal: CPX-11159
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| JMJD6 | Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (EC 1.14.11.-) (Histone arginine demethylase JMJD6) (JmjC domain-containing protein 6) (Jumonji domain-containing protein 6) (Lysyl-hydroxylase JMJD6) (Peptide-lysine 5-dioxygenase JMJD6) (Phosphatidylserine receptor) (Protein PTDSR) | 5 | UniProt NCBI |
| PUF60 | Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) (FUSE-binding protein-interacting repressor) (FBP-interacting repressor) (Ro-binding protein 1) (RoBP1) (Siah-binding protein 1) (Siah-BP1) | 5 | UniProt NCBI |
| RBM25 | RNA-binding protein 25 (Arg/Glu/Asp-rich protein of 120 kDa) (RED120) (Protein S164) (RNA-binding motif protein 25) (RNA-binding region-containing protein 7) | 5 | UniProt NCBI |
| PHRF1 | PHD and RING finger domain-containing protein 1 | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03040 | 0.0192212154966 | 0.5 | PUF60 RBM25 | Spliceosome |
| GO:0048024 | 0.0364824972322 | 0.75 | JMJD6 PUF60 RBM25 | regulation of mRNA splicing, via spliceosome |
| CORUM:351 | 0.047170241778 | 0.5 | PUF60 RBM25 | Spliceosome |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| JMJD6 | RBM25 | 0.999 | 0.122 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| JMJD6 | PHRF1 | 0.998 | 0.05 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| PUF60 | JMJD6 | 0.993 | 0.126 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 fraction | |
| PUF60 | RBM25 | 0.963 | 0.694 |
structurally_consistent (O95232)
|
bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| PHRF1 | RBM25 | 0.758 | 0.24 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only boldt_WMM | |
| PUF60 | PHRF1 | 0.154 | 0.492 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
Related Complexes