hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_05336.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ITGB1 | Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29) | 5 | UniProt NCBI |
| ITGA8 | Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2439 | 1.70876175213e-06 | 1.0 | ITGB1 ITGA8 | ITGA8-ITGB1 complex |
| WP:WP4823 | 0.000238782367243 | 1.0 | ITGB1 ITGA8 | Genes controlling nephrogenesis |
| KEGG:04512 | 0.000359441594481 | 1.0 | ITGB1 ITGA8 | ECM-receptor interaction |
| KEGG:05412 | 0.00037033376401 | 1.0 | ITGB1 ITGA8 | Arrhythmogenic right ventricular cardiomyopathy |
| WP:WP5053 | 0.000460113616736 | 1.0 | ITGB1 ITGA8 | Development of ureteric collection system |
| KEGG:05414 | 0.000463323629249 | 1.0 | ITGB1 ITGA8 | Dilated cardiomyopathy |
| KEGG:05410 | 0.000463323629249 | 1.0 | ITGB1 ITGA8 | Hypertrophic cardiomyopathy |
| GO:0034678 | 0.000468200720083 | 1.0 | ITGB1 ITGA8 | integrin alpha8-beta1 complex |
| REAC:R-HSA-2129379 | 0.000693757271364 | 1.0 | ITGB1 ITGA8 | Molecules associated with elastic fibres |
| WP:WP2118 | 0.000728264938239 | 1.0 | ITGB1 ITGA8 | Arrhythmogenic right ventricular cardiomyopathy |
| KEGG:04514 | 0.000870723283599 | 1.0 | ITGB1 ITGA8 | Cell adhesion molecules |
| REAC:R-HSA-1566948 | 0.00107651990384 | 1.0 | ITGB1 ITGA8 | Elastic fibre formation |
| REAC:R-HSA-2173789 | 0.00140118463675 | 1.0 | ITGB1 ITGA8 | TGF-beta receptor signaling activates SMADs |
| WP:WP185 | 0.00148377064565 | 1.0 | ITGB1 ITGA8 | Integrin mediated cell adhesion |
| WP:WP4541 | 0.00194090480325 | 1.0 | ITGB1 ITGA8 | Hippo Merlin signaling dysregulation |
| KEGG:04510 | 0.00241871191437 | 1.0 | ITGB1 ITGA8 | Focal adhesion |
| REAC:R-HSA-3000178 | 0.00282458317627 | 1.0 | ITGB1 ITGA8 | ECM proteoglycans |
| KEGG:04810 | 0.00307500577096 | 1.0 | ITGB1 ITGA8 | Regulation of actin cytoskeleton |
| REAC:R-HSA-216083 | 0.00333721170191 | 1.0 | ITGB1 ITGA8 | Integrin cell surface interactions |
| KEGG:03271 | 0.00475142446038 | 0.5 | ITGB1 | Virion - Rotavirus |
| WP:WP306 | 0.00633262755764 | 1.0 | ITGB1 ITGA8 | Focal adhesion |
| REAC:R-HSA-170834 | 0.00639247771471 | 1.0 | ITGB1 ITGA8 | Signaling by TGF-beta Receptor Complex |
| KEGG:04151 | 0.00662552789826 | 1.0 | ITGB1 ITGA8 | PI3K-Akt signaling pathway |
| KEGG:05165 | 0.00700203931066 | 1.0 | ITGB1 ITGA8 | Human papillomavirus infection |
| REAC:R-HSA-9006936 | 0.0098732254038 | 1.0 | ITGB1 ITGA8 | Signaling by TGFB family members |
| WP:WP3932 | 0.0130364105952 | 1.0 | ITGB1 ITGA8 | Focal adhesion PI3K Akt mTOR signaling pathway |
| WP:WP4172 | 0.015571930313 | 1.0 | ITGB1 ITGA8 | PI3K Akt signaling pathway |
| CORUM:2431 | 0.0249718442457 | 0.5 | ITGB1 | ITGA2-ITGB1-COL6A3 complex |
| CORUM:3057 | 0.0249718442457 | 0.5 | ITGB1 | ITGA10-ITGB1 complex |
| CORUM:3058 | 0.0249718442457 | 0.5 | ITGB1 | ITGA11-ITGB1 complex |
| CORUM:2426 | 0.0249718442457 | 0.5 | ITGB1 | ITGA4-ITGB1-THBS1 complex |
| CORUM:3035 | 0.0249718442457 | 0.5 | ITGB1 | LAT2-ITGB1 complex |
| CORUM:2432 | 0.0249718442457 | 0.5 | ITGB1 | ITGA2-ITGB1 complex |
| CORUM:2418 | 0.0249718442457 | 0.5 | ITGB1 | ITGA4-ITGB1 complex |
| CORUM:2413 | 0.0249718442457 | 0.5 | ITGB1 | ITGA6-ITGB1 complex |
| CORUM:2421 | 0.0249718442457 | 0.5 | ITGB1 | ITGA4-ITGB1-VCAM1 complex |
| GO:0048333 | 0.0365196561665 | 1.0 | ITGB1 ITGA8 | mesodermal cell differentiation |
| REAC:R-HSA-1474244 | 0.0442193366216 | 1.0 | ITGB1 ITGA8 | Extracellular matrix organization |
| CORUM:2972 | 0.0499419797295 | 0.5 | ITGB1 | ITGA9-ITGB1-VEGFA complex |
| CORUM:2971 | 0.0499419797295 | 0.5 | ITGB1 | ITGA9-ITGB1-VEGFC complex |
| CORUM:2989 | 0.0499419797295 | 0.5 | ITGB1 | ITGA9-ITGB1-ADAM8 complex |
| CORUM:7012 | 0.0499419797295 | 0.5 | ITGB1 | ITGB1-RACK1 complex |
| CORUM:3104 | 0.0499419797295 | 0.5 | ITGB1 | ITGB1-NRP1 complex |
| CORUM:3111 | 0.0499419797295 | 0.5 | ITGB1 | ITGA9-ITGB1-SPP1 complex |
| CORUM:3112 | 0.0499419797295 | 0.5 | ITGB1 | ITGA5-ITGB1-SPP1 complex |
| CORUM:2885 | 0.0499419797295 | 0.5 | ITGB1 | ITGAV-ITGB1-SPP1 complex |
| CORUM:3059 | 0.0499419797295 | 0.5 | ITGB1 | ITGA11-ITGB1-COL1A1 complex |
| CORUM:2447 | 0.0499419797295 | 0.5 | ITGB1 | ITGA9-ITGB1-ADAM12 complex |
| CORUM:2430 | 0.0499419797295 | 0.5 | ITGB1 | ITGA2-ITGB1-CHAD complex |
| CORUM:2443 | 0.0499419797295 | 0.5 | ITGB1 | ITGA9-ITGB1-TNC complex |
| CORUM:2385 | 0.0499419797295 | 0.5 | ITGB1 | ITGA5-ITGB4 complex |
| CORUM:2390 | 0.0499419797295 | 0.5 | ITGB1 | CD98-LAT2-ITGB1 complex |
| CORUM:2397 | 0.0499419797295 | 0.5 | ITGB1 | ITGA7-ITGB1-ITGB1BP3 complex |
| CORUM:2401 | 0.0499419797295 | 0.5 | ITGB1 | ITGA3-ITGB1-THBS1 complex |
| CORUM:2406 | 0.0499419797295 | 0.5 | ITGB1 | ITGA3-ITGB1 complex |
| CORUM:2411 | 0.0499419797295 | 0.5 | ITGB1 | ITGA6-ITGB1-CD151 complex |
| CORUM:2417 | 0.0499419797295 | 0.5 | ITGB1 | ITGA4-ITGB1-EMILIN1 complex |
| CORUM:2419 | 0.0499419797295 | 0.5 | ITGB1 | ITGA4-ITGB1-CD81 complex |
| CORUM:2444 | 0.0499419797295 | 0.5 | ITGB1 | ITGB1-ITGA9 complex |
| CORUM:2420 | 0.0499419797295 | 0.5 | ITGB1 | ITGA4-ITGB1-CD53 complex |
| CORUM:2423 | 0.0499419797295 | 0.5 | ITGB1 | ITGA4-ITGB1-CD47 complex |
| CORUM:2428 | 0.0499419797295 | 0.5 | ITGB1 | ITGA4-ITGB1-THBS2 complex |
| CORUM:2429 | 0.0499419797295 | 0.5 | ITGB1 | ITGA2-ITGB1-CD47 complex |
| CORUM:2434 | 0.0499419797295 | 0.5 | ITGB1 | ITGA1-ITGB1-COL6A3 complex |
| CORUM:2435 | 0.0499419797295 | 0.5 | ITGB1 | ITGA1-ITGB1-PTPN2 complex |
| CORUM:2436 | 0.0499419797295 | 0.5 | ITGB1 | ITGAV-ITGB1 complex |
| CORUM:2437 | 0.0499419797295 | 0.5 | ITGB1 | ITGA6-ITGB1-CYR61 complex |
| CORUM:2442 | 0.0499419797295 | 0.5 | ITGB1 | ITGA9-ITGB1-VCAM1 complex |
| CORUM:2422 | 0.0499419797295 | 0.5 | ITGB1 | ITGA4-ITGB1-JAM2 complex |
| CORUM:2424 | 0.0499419797295 | 0.5 | ITGB1 | ITGA4-ITGB1-CD63 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ITGB1 | ITGA8 | 0.989 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM fraction |
Related Complexes