hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_05366.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SPOP | Speckle-type POZ protein (HIB homolog 1) (Roadkill homolog 1) | 5 | UniProt NCBI |
| KPNA5 | Importin subunit alpha-6 (Karyopherin subunit alpha-5) | 5 | UniProt NCBI |
| WDHD1 | WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA-binding protein 1) (And-1) | 5 | UniProt NCBI |
| NUP50 | Nuclear pore complex protein Nup50 (50 kDa nucleoporin) (Nuclear pore-associated protein 60 kDa-like) (Nucleoporin Nup50) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-168276 | 0.0068064250699 | 0.5 | NUP50 KPNA5 | NS1 Mediated Effects on Host Pathways |
| KEGG:03013 | 0.0125523722118 | 0.5 | NUP50 KPNA5 | Nucleocytoplasmic transport |
| REAC:R-HSA-1169408 | 0.0218635493976 | 0.5 | NUP50 KPNA5 | ISG15 antiviral mechanism |
| REAC:R-HSA-1169410 | 0.0260384914588 | 0.5 | NUP50 KPNA5 | Antiviral mechanism by IFN-stimulated genes |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| NUP50 | KPNA5 | 0.998 | 0.166 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
| SPOP | NUP50 | 0.997 | 0.154 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM |
| SPOP | KPNA5 | 0.994 | 0.066 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| NUP50 | WDHD1 | 0.963 | 0.134 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction |
| SPOP | WDHD1 | 0.206 | 0.114 | bioplex_WMM bioplex3_WMM WMM_only |
| KPNA5 | WDHD1 | 0.039 | 0.144 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes