List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_05382.1

Confidence: Extremely High   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
EXOSC3	Exosome complex component RRP40 (Exosome component 3) (Ribosomal RNA-processing protein 40) (p10)	5	UniProt   NCBI
DIS3	Exosome complex exonuclease RRP44 (EC 3.1.13.-) (EC 3.1.26.-) (Protein DIS3 homolog) (Ribosomal RNA-processing protein 44)	5	UniProt   NCBI
EXOSC7	Exosome complex component RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42) (p8)	5	UniProt   NCBI
MTREX	Exosome RNA helicase MTR4 (EC 3.6.4.13) (ATP-dependent RNA helicase DOB1) (ATP-dependent RNA helicase SKIV2L2) (Superkiller viralicidic activity 2-like 2) (TRAMP-like complex helicase)	5	UniProt   NCBI
DIS3L	DIS3-like exonuclease 1 (EC 3.1.13.1)	5	UniProt   NCBI
EXOSC8	Exosome complex component RRP43 (Exosome component 8) (Opa-interacting protein 2) (OIP-2) (Ribosomal RNA-processing protein 43) (p9)	5	UniProt   NCBI
EXOSC4	Exosome complex component RRP41 (Exosome component 4) (Ribosomal RNA-processing protein 41) (p12A)	5	UniProt   NCBI
EXOSC1	Exosome complex component CSL4 (Exosome component 1)	5	UniProt   NCBI
MPHOSPH6	M-phase phosphoprotein 6	5	UniProt   NCBI
EXOSC6	Exosome complex component MTR3 (Exosome component 6) (mRNA transport regulator 3 homolog) (hMtr3) (p11)	5	UniProt   NCBI
EXOSC5	Exosome complex component RRP46 (Chronic myelogenous leukemia tumor antigen 28) (Exosome component 5) (Ribosomal RNA-processing protein 46) (p12B)	5	UniProt   NCBI
EXOSC2	Exosome complex component RRP4 (Exosome component 2) (Ribosomal RNA-processing protein 4)	5	UniProt   NCBI
EXOSC10	Exosome complex component 10 (EC 3.1.13.-) (Autoantigen PM/Scl 2) (P100 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 100 kDa) (PM/Scl-100) (Polymyositis/scleroderma autoantigen 2)	5	UniProt   NCBI
ZCCHC8	Zinc finger CCHC domain-containing protein 8 (TRAMP-like complex RNA-binding factor ZCCHC8)	5	UniProt   NCBI
RBM7	RNA-binding protein 7 (RNA-binding motif protein 7)	5	UniProt   NCBI
C1D	Nuclear nucleic acid-binding protein C1D (hC1D)	5	UniProt   NCBI
HBS1L	HBS1-like protein (EC 3.6.5.-) (ERFS)	5	UniProt   NCBI
EXOSC9	Exosome complex component RRP45 (Autoantigen PM/Scl 1) (Exosome component 9) (P75 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 1) (Polymyositis/scleroderma autoantigen 75 kDa) (PM/Scl-75)	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0000176	7.93561129389e-38	0.777777777778	EXOSC3 EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 EXOSC5 EXOSC2 MTREX DIS3 EXOSC8 C1D EXOSC7 EXOSC6	nuclear exosome (RNase complex)
GO:1905354	8.87367353689e-38	0.833333333333	EXOSC3 EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 EXOSC5 EXOSC2 DIS3 MTREX EXOSC8 DIS3L C1D EXOSC7 EXOSC6	exoribonuclease complex
GO:0000178	8.87367353689e-38	0.833333333333	EXOSC3 EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 EXOSC5 EXOSC2 DIS3 MTREX EXOSC8 DIS3L C1D EXOSC7 EXOSC6	exosome (RNase complex)
CORUM:7443	3.79256257707e-36	0.666666666667	EXOSC3 EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 EXOSC5 EXOSC2 DIS3L EXOSC8 EXOSC7 EXOSC6	Exosome
CORUM:789	7.91236912508e-33	0.611111111111	EXOSC3 EXOSC4 EXOSC10 EXOSC5 EXOSC1 EXOSC9 EXOSC2 DIS3 EXOSC8 EXOSC7 EXOSC6	Exosome
KEGG:03018	3.06665996634e-31	0.833333333333	EXOSC3 EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 EXOSC5 EXOSC2 DIS3 MTREX EXOSC8 DIS3L C1D EXOSC7 EXOSC6	RNA degradation
GO:0000177	8.54607668716e-30	0.666666666667	EXOSC3 EXOSC4 EXOSC10 EXOSC5 EXOSC1 EXOSC9 EXOSC2 DIS3 EXOSC8 DIS3L EXOSC7 EXOSC6	cytoplasmic exosome (RNase complex)
CORUM:788	1.4445018884e-29	0.555555555556	EXOSC3 EXOSC4 EXOSC5 EXOSC1 EXOSC9 EXOSC2 DIS3 EXOSC8 EXOSC7 EXOSC6	Exosome
GO:0034661	2.24143487516e-28	0.777777777778	EXOSC3 EXOSC4 EXOSC10 EXOSC5 ZCCHC8 EXOSC9 RBM7 EXOSC2 DIS3 MTREX EXOSC8 DIS3L EXOSC7 EXOSC6	ncRNA catabolic process
REAC:R-HSA-429958	2.63962005712e-28	0.611111111111	EXOSC3 EXOSC4 EXOSC5 EXOSC1 EXOSC9 EXOSC2 HBS1L DIS3 EXOSC8 EXOSC7 EXOSC6	mRNA decay by 3' to 5' exoribonuclease
GO:0101019	1.79118234161e-26	0.555555555556	EXOSC3 EXOSC4 EXOSC5 EXOSC1 EXOSC9 EXOSC2 EXOSC8 EXOSC6 EXOSC7 EXOSC10	nucleolar exosome (RNase complex)
GO:0016075	3.11276777535e-25	0.611111111111	EXOSC3 EXOSC4 EXOSC10 EXOSC5 EXOSC9 EXOSC2 DIS3 EXOSC8 DIS3L EXOSC7 EXOSC6	rRNA catabolic process
REAC:R-HSA-450513	8.82776501204e-25	0.555555555556	EXOSC3 EXOSC4 EXOSC5 EXOSC1 EXOSC9 EXOSC2 DIS3 EXOSC8 EXOSC7 EXOSC6	Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
REAC:R-HSA-450385	2.14281784057e-24	0.555555555556	EXOSC3 EXOSC4 EXOSC5 EXOSC1 EXOSC9 EXOSC2 DIS3 EXOSC8 EXOSC7 EXOSC6	Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
REAC:R-HSA-450604	2.14281784057e-24	0.555555555556	EXOSC3 EXOSC4 EXOSC5 EXOSC1 EXOSC9 EXOSC2 DIS3 EXOSC8 EXOSC7 EXOSC6	KSRP (KHSRP) binds and destabilizes mRNA
GO:0006401	2.15735911719e-22	0.888888888889	EXOSC3 HBS1L EXOSC4 EXOSC10 EXOSC5 EXOSC1 EXOSC9 RBM7 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 EXOSC7 EXOSC6	RNA catabolic process
REAC:R-HSA-380994	5.8263773628e-22	0.555555555556	EXOSC3 EXOSC4 EXOSC5 EXOSC1 EXOSC9 EXOSC2 DIS3 EXOSC8 EXOSC7 EXOSC6	ATF4 activates genes in response to endoplasmic reticulum stress
GO:0016073	9.55923379011e-22	0.666666666667	EXOSC3 EXOSC4 EXOSC5 ZCCHC8 EXOSC9 RBM7 EXOSC2 MTREX EXOSC8 EXOSC6 EXOSC7 EXOSC10	snRNA metabolic process
REAC:R-HSA-6791226	1.00165072425e-21	0.777777777778	EXOSC3 EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 EXOSC5 EXOSC2 MTREX DIS3 EXOSC8 C1D EXOSC7 EXOSC6	Major pathway of rRNA processing in the nucleolus and cytosol
REAC:R-HSA-8868773	2.19018122976e-21	0.777777777778	EXOSC3 EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 EXOSC5 EXOSC2 MTREX DIS3 EXOSC8 C1D EXOSC7 EXOSC6	rRNA processing in the nucleus and cytosol
REAC:R-HSA-72312	4.59338796312e-21	0.777777777778	EXOSC3 EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 EXOSC5 EXOSC2 MTREX DIS3 EXOSC8 C1D EXOSC7 EXOSC6	rRNA processing
REAC:R-HSA-381042	4.85282144747e-21	0.555555555556	EXOSC3 EXOSC4 EXOSC5 EXOSC1 EXOSC9 EXOSC2 DIS3 EXOSC8 EXOSC7 EXOSC6	PERK regulates gene expression
REAC:R-HSA-429914	7.107716399e-21	0.611111111111	EXOSC3 EXOSC4 EXOSC5 EXOSC1 EXOSC9 EXOSC2 HBS1L DIS3 EXOSC8 EXOSC7 EXOSC6	Deadenylation-dependent mRNA decay
GO:0034475	4.2460941064e-20	0.444444444444	EXOSC3 EXOSC4 EXOSC5 EXOSC9 EXOSC2 EXOSC8 EXOSC6 EXOSC7	U4 snRNA 3'-end processing
GO:0071027	5.80347292239e-20	0.5	EXOSC3 EXOSC4 EXOSC5 EXOSC9 EXOSC2 EXOSC8 EXOSC6 EXOSC7 EXOSC10	nuclear RNA surveillance
GO:0071025	3.31259193036e-19	0.5	EXOSC3 EXOSC4 EXOSC5 EXOSC9 EXOSC2 EXOSC8 EXOSC6 EXOSC7 EXOSC10	RNA surveillance
GO:0034655	3.70625050928e-19	0.888888888889	EXOSC3 HBS1L EXOSC4 EXOSC10 EXOSC5 EXOSC1 EXOSC9 RBM7 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 EXOSC7 EXOSC6	nucleobase-containing compound catabolic process
GO:0016072	6.92218913145e-19	0.777777777778	EXOSC3 EXOSC4 EXOSC10 MPHOSPH6 EXOSC9 EXOSC5 EXOSC2 DIS3 MTREX EXOSC8 DIS3L C1D EXOSC7 EXOSC6	rRNA metabolic process
GO:0046700	1.14041828745e-18	0.888888888889	EXOSC3 HBS1L EXOSC4 EXOSC10 EXOSC5 EXOSC1 EXOSC9 RBM7 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 EXOSC7 EXOSC6	heterocycle catabolic process
GO:0044270	1.18542643987e-18	0.888888888889	EXOSC3 HBS1L EXOSC4 EXOSC10 EXOSC5 EXOSC1 EXOSC9 RBM7 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 EXOSC7 EXOSC6	cellular nitrogen compound catabolic process
GO:0019439	1.43654049555e-18	0.888888888889	EXOSC3 HBS1L EXOSC4 EXOSC10 EXOSC5 EXOSC1 EXOSC9 RBM7 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 EXOSC7 EXOSC6	aromatic compound catabolic process
GO:0000460	1.63903999371e-18	0.555555555556	EXOSC3 EXOSC4 MPHOSPH6 EXOSC9 EXOSC10 MTREX EXOSC2 EXOSC8 EXOSC7 C1D	maturation of 5.8S rRNA
GO:1901361	2.61667558916e-18	0.888888888889	EXOSC3 HBS1L EXOSC4 EXOSC10 EXOSC5 EXOSC1 EXOSC9 RBM7 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 EXOSC7 EXOSC6	organic cyclic compound catabolic process
GO:0000291	4.85270251669e-18	0.5	EXOSC3 EXOSC4 EXOSC5 EXOSC9 EXOSC2 DIS3 EXOSC8 EXOSC6 EXOSC7	nuclear-transcribed mRNA catabolic process, exonucleolytic
GO:0034427	6.99327205182e-18	0.444444444444	EXOSC3 EXOSC4 EXOSC5 EXOSC9 EXOSC2 EXOSC8 EXOSC6 EXOSC7	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
REAC:R-HSA-8953854	1.93563116758e-17	0.888888888889	EXOSC3 EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC5 EXOSC2 HBS1L MTREX DIS3 EXOSC8 C1D EXOSC7 EXOSC6	Metabolism of RNA
GO:0034660	3.12671114308e-17	0.888888888889	EXOSC3 EXOSC4 EXOSC10 MPHOSPH6 ZCCHC8 EXOSC9 RBM7 EXOSC5 EXOSC2 DIS3 MTREX EXOSC8 DIS3L C1D EXOSC7 EXOSC6	ncRNA metabolic process
GO:0006396	1.25620432614e-16	0.944444444444	EXOSC3 EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC5 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 C1D EXOSC7 EXOSC6	RNA processing
REAC:R-HSA-450531	2.59312368793e-16	0.555555555556	EXOSC3 EXOSC4 EXOSC5 EXOSC1 EXOSC9 EXOSC2 DIS3 EXOSC8 EXOSC7 EXOSC6	Regulation of mRNA stability by proteins that bind AU-rich elements
REAC:R-HSA-381119	2.94207373984e-16	0.555555555556	EXOSC3 EXOSC4 EXOSC5 EXOSC1 EXOSC9 EXOSC2 DIS3 EXOSC8 EXOSC7 EXOSC6	Unfolded Protein Response (UPR)
GO:0000175	2.02307052552e-15	0.5	EXOSC3 EXOSC4 EXOSC5 EXOSC9 EXOSC2 DIS3 DIS3L EXOSC7 EXOSC10	3'-5'-RNA exonuclease activity
GO:0034470	2.30471205352e-15	0.777777777778	EXOSC3 EXOSC4 EXOSC10 MPHOSPH6 ZCCHC8 EXOSC9 EXOSC5 EXOSC2 MTREX DIS3 EXOSC8 C1D EXOSC7 EXOSC6	ncRNA processing
GO:0006364	2.69787238713e-15	0.666666666667	EXOSC3 EXOSC4 MPHOSPH6 EXOSC9 EXOSC5 EXOSC2 MTREX DIS3 EXOSC8 C1D EXOSC7 EXOSC10	rRNA processing
GO:0000956	4.92460004172e-15	0.611111111111	EXOSC3 HBS1L EXOSC4 EXOSC5 EXOSC9 EXOSC2 DIS3 EXOSC8 EXOSC6 EXOSC7 EXOSC10	nuclear-transcribed mRNA catabolic process
GO:0016896	6.05839034698e-15	0.5	EXOSC3 EXOSC4 EXOSC5 EXOSC9 EXOSC2 DIS3 DIS3L EXOSC7 EXOSC10	RNA exonuclease activity, producing 5'-phosphomonoesters
GO:0071028	6.75320850932e-15	0.388888888889	EXOSC4 EXOSC5 EXOSC9 EXOSC10 EXOSC8 EXOSC6 EXOSC7	nuclear mRNA surveillance
GO:0004532	7.81293528955e-15	0.5	EXOSC3 EXOSC4 EXOSC5 EXOSC9 EXOSC2 DIS3 DIS3L EXOSC7 EXOSC10	RNA exonuclease activity
GO:0034472	8.57225015028e-15	0.444444444444	EXOSC3 EXOSC4 EXOSC5 EXOSC9 EXOSC2 EXOSC8 EXOSC6 EXOSC7	snRNA 3'-end processing
GO:0016180	6.56124649302e-14	0.444444444444	EXOSC3 EXOSC4 EXOSC5 EXOSC9 EXOSC2 EXOSC8 EXOSC6 EXOSC7	snRNA processing
GO:0043928	9.6380081533e-14	0.388888888889	EXOSC3 EXOSC5 EXOSC9 DIS3 EXOSC8 EXOSC2 EXOSC7	exonucleolytic catabolism of deadenylated mRNA
GO:0008408	1.04422891962e-13	0.5	EXOSC3 EXOSC4 EXOSC5 EXOSC9 EXOSC2 DIS3 DIS3L EXOSC7 EXOSC10	3'-5' exonuclease activity
GO:0016796	1.25712195078e-13	0.5	EXOSC3 EXOSC4 EXOSC5 EXOSC9 EXOSC2 DIS3 DIS3L EXOSC7 EXOSC10	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
GO:0071046	4.80196613796e-13	0.333333333333	EXOSC3 EXOSC10 EXOSC8 EXOSC9 EXOSC2 EXOSC7	nuclear polyadenylation-dependent ncRNA catabolic process
GO:0071029	4.80196613796e-13	0.333333333333	EXOSC3 EXOSC10 EXOSC8 EXOSC9 EXOSC2 EXOSC7	nuclear ncRNA surveillance
GO:0071035	4.80196613796e-13	0.333333333333	EXOSC3 EXOSC10 EXOSC8 EXOSC9 EXOSC2 EXOSC7	nuclear polyadenylation-dependent rRNA catabolic process
GO:0071038	4.80196613796e-13	0.333333333333	EXOSC3 EXOSC10 EXOSC8 EXOSC9 EXOSC2 EXOSC7	nuclear polyadenylation-dependent tRNA catabolic process
GO:0042254	4.95752969623e-13	0.666666666667	EXOSC3 EXOSC4 MPHOSPH6 EXOSC9 EXOSC5 EXOSC2 MTREX DIS3 EXOSC8 C1D EXOSC7 EXOSC10	ribosome biogenesis
GO:0016071	1.43354447292e-12	0.777777777778	EXOSC3 EXOSC4 EXOSC10 EXOSC5 ZCCHC8 EXOSC9 RBM7 EXOSC2 HBS1L MTREX DIS3 EXOSC8 EXOSC7 EXOSC6	mRNA metabolic process
GO:0043633	1.91943403175e-12	0.333333333333	EXOSC3 EXOSC10 EXOSC8 EXOSC9 EXOSC2 EXOSC7	polyadenylation-dependent RNA catabolic process
GO:0106354	1.91943403175e-12	0.333333333333	EXOSC3 EXOSC10 EXOSC8 EXOSC9 EXOSC2 EXOSC7	tRNA surveillance
GO:0043634	1.91943403175e-12	0.333333333333	EXOSC3 EXOSC10 EXOSC8 EXOSC9 EXOSC2 EXOSC7	polyadenylation-dependent ncRNA catabolic process
GO:0071051	1.91943403175e-12	0.333333333333	EXOSC3 EXOSC4 EXOSC10 EXOSC5 EXOSC2 EXOSC6	polyadenylation-dependent snoRNA 3'-end processing
GO:0004527	2.38902308173e-12	0.5	EXOSC3 EXOSC4 EXOSC5 EXOSC9 EXOSC2 DIS3 DIS3L EXOSC7 EXOSC10	exonuclease activity
GO:0009057	2.97216395219e-12	0.888888888889	EXOSC3 HBS1L EXOSC4 EXOSC10 EXOSC5 EXOSC1 EXOSC9 RBM7 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 EXOSC7 EXOSC6	macromolecule catabolic process
GO:0006402	4.13449853282e-12	0.611111111111	EXOSC3 HBS1L EXOSC4 EXOSC5 EXOSC9 EXOSC2 DIS3 EXOSC8 EXOSC6 EXOSC7 EXOSC10	mRNA catabolic process
GO:0000467	5.75424749836e-12	0.333333333333	EXOSC3 EXOSC10 EXOSC8 EXOSC9 EXOSC2 EXOSC7	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0031123	1.02643496282e-11	0.5	EXOSC3 EXOSC4 EXOSC5 EXOSC9 EXOSC2 EXOSC8 EXOSC6 EXOSC7 EXOSC10	RNA 3'-end processing
GO:0031125	1.43754889331e-11	0.333333333333	EXOSC3 EXOSC10 EXOSC8 EXOSC9 EXOSC2 EXOSC7	rRNA 3'-end processing
GO:0044248	1.99605943164e-11	0.888888888889	EXOSC3 HBS1L EXOSC4 EXOSC10 EXOSC5 EXOSC1 EXOSC9 RBM7 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 EXOSC7 EXOSC6	cellular catabolic process
GO:0031126	6.31630970508e-11	0.333333333333	EXOSC3 EXOSC4 EXOSC10 EXOSC5 EXOSC2 EXOSC6	sno(s)RNA 3'-end processing
GO:0004540	6.32236288067e-11	0.5	EXOSC3 EXOSC4 EXOSC5 EXOSC9 EXOSC2 DIS3 DIS3L EXOSC7 EXOSC10	RNA nuclease activity
GO:0022613	9.42457014282e-11	0.666666666667	EXOSC3 EXOSC4 MPHOSPH6 EXOSC9 EXOSC5 EXOSC2 MTREX DIS3 EXOSC8 C1D EXOSC7 EXOSC10	ribonucleoprotein complex biogenesis
GO:0043144	1.17220283024e-10	0.333333333333	EXOSC3 EXOSC4 EXOSC10 EXOSC5 EXOSC2 EXOSC6	sno(s)RNA processing
GO:0016074	3.4141106807e-10	0.333333333333	EXOSC3 EXOSC4 EXOSC10 EXOSC5 EXOSC2 EXOSC6	sno(s)RNA metabolic process
GO:0016078	3.4141106807e-10	0.333333333333	EXOSC3 EXOSC10 EXOSC8 EXOSC9 EXOSC2 EXOSC7	tRNA catabolic process
GO:0140513	4.59311953737e-10	0.833333333333	EXOSC3 EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 EXOSC5 EXOSC2 MTREX DIS3 EXOSC8 ZCCHC8 C1D EXOSC7 EXOSC6	nuclear protein-containing complex
GO:1901575	9.01346602197e-10	0.888888888889	EXOSC3 HBS1L EXOSC4 EXOSC10 EXOSC5 EXOSC1 EXOSC9 RBM7 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 EXOSC7 EXOSC6	organic substance catabolic process
GO:1902494	1.18339565857e-09	0.888888888889	EXOSC3 EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 EXOSC5 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 C1D EXOSC7 EXOSC6	catalytic complex
GO:0004518	4.02456007246e-09	0.5	EXOSC3 EXOSC4 EXOSC5 EXOSC9 EXOSC2 DIS3 DIS3L EXOSC7 EXOSC10	nuclease activity
GO:0000466	5.06460633388e-09	0.333333333333	EXOSC3 EXOSC10 EXOSC8 EXOSC9 EXOSC2 EXOSC7	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000288	2.67428639577e-08	0.388888888889	EXOSC3 EXOSC5 EXOSC9 DIS3 EXOSC8 EXOSC2 EXOSC7	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0009056	2.96768591454e-08	0.888888888889	EXOSC3 HBS1L EXOSC4 EXOSC10 EXOSC5 EXOSC1 EXOSC9 RBM7 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 EXOSC7 EXOSC6	catabolic process
GO:0140098	3.63899771998e-08	0.555555555556	EXOSC3 EXOSC4 EXOSC5 EXOSC9 EXOSC2 MTREX DIS3 DIS3L EXOSC7 EXOSC10	catalytic activity, acting on RNA
CORUM:7349	6.32531883213e-08	0.166666666667	ZCCHC8 MTREX RBM7	MTR4-RBM7-ZCCHC8 complex
GO:0016070	7.83970113024e-08	1.0	EXOSC3 HBS1L EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC5 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 C1D EXOSC7 EXOSC6	RNA metabolic process
GO:0061157	3.68047434671e-07	0.388888888889	EXOSC3 EXOSC5 EXOSC9 DIS3 EXOSC8 EXOSC2 EXOSC7	mRNA destabilization
GO:0005730	3.76973261247e-07	0.666666666667	EXOSC3 EXOSC4 MPHOSPH6 EXOSC1 EXOSC9 EXOSC5 EXOSC2 C1D EXOSC6 EXOSC8 EXOSC7 EXOSC10	nucleolus
GO:0016076	4.02274655956e-07	0.222222222222	RBM7 EXOSC10 MTREX ZCCHC8	snRNA catabolic process
GO:0071034	4.02274655956e-07	0.222222222222	EXOSC3 EXOSC2 EXOSC10 DIS3	CUT catabolic process
GO:0071043	4.02274655956e-07	0.222222222222	EXOSC3 EXOSC2 EXOSC10 DIS3	CUT metabolic process
GO:0050779	4.67021511839e-07	0.388888888889	EXOSC3 EXOSC5 EXOSC9 DIS3 EXOSC8 EXOSC2 EXOSC7	RNA destabilization
GO:0061014	5.04700702078e-07	0.388888888889	EXOSC3 EXOSC5 EXOSC9 DIS3 EXOSC8 EXOSC2 EXOSC7	positive regulation of mRNA catabolic process
GO:0090304	7.16456735392e-07	1.0	EXOSC3 HBS1L EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC5 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 C1D EXOSC7 EXOSC6	nucleic acid metabolic process
REAC:R-HSA-2262752	7.77248508899e-07	0.555555555556	EXOSC3 EXOSC4 EXOSC5 EXOSC1 EXOSC9 EXOSC2 DIS3 EXOSC8 EXOSC7 EXOSC6	Cellular responses to stress
REAC:R-HSA-8953897	8.53270543113e-07	0.555555555556	EXOSC3 EXOSC4 EXOSC5 EXOSC1 EXOSC9 EXOSC2 DIS3 EXOSC8 EXOSC7 EXOSC6	Cellular responses to stimuli
GO:1903313	2.4464943099e-06	0.388888888889	EXOSC3 EXOSC5 EXOSC9 DIS3 EXOSC8 EXOSC2 EXOSC7	positive regulation of mRNA metabolic process
GO:0140640	3.05227842408e-06	0.555555555556	EXOSC3 EXOSC4 EXOSC5 EXOSC9 EXOSC2 MTREX DIS3 DIS3L EXOSC7 EXOSC10	catalytic activity, acting on a nucleic acid
GO:0006139	4.78635215296e-06	1.0	EXOSC3 HBS1L EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC5 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 C1D EXOSC7 EXOSC6	nucleobase-containing compound metabolic process
GO:0010629	5.98989777901e-06	0.611111111111	EXOSC3 HBS1L EXOSC4 EXOSC5 EXOSC9 EXOSC2 DIS3 EXOSC8 EXOSC6 EXOSC7 EXOSC10	negative regulation of gene expression
CORUM:822	7.54956890187e-06	0.166666666667	EXOSC2 EXOSC4 EXOSC10	mRNA decay complex (UPF1, UPF2, UPF3B, DCP2, XRN1, XRN2, EXOSC2, EXOSC4, EXOSC10, PARN)
GO:0046483	8.09121800114e-06	1.0	EXOSC3 HBS1L EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC5 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 C1D EXOSC7 EXOSC6	heterocycle metabolic process
GO:0006725	8.55697619319e-06	1.0	EXOSC3 HBS1L EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC5 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 C1D EXOSC7 EXOSC6	cellular aromatic compound metabolic process
GO:1903311	8.6453392527e-06	0.444444444444	EXOSC3 EXOSC5 EXOSC9 RBM7 DIS3 EXOSC8 EXOSC2 EXOSC7	regulation of mRNA metabolic process
GO:0043488	8.81640211506e-06	0.388888888889	EXOSC3 EXOSC5 EXOSC9 DIS3 EXOSC8 EXOSC2 EXOSC7	regulation of mRNA stability
GO:0043487	1.4392966413e-05	0.388888888889	EXOSC3 EXOSC5 EXOSC9 DIS3 EXOSC8 EXOSC2 EXOSC7	regulation of RNA stability
GO:0003723	1.46843876871e-05	0.722222222222	EXOSC3 EXOSC4 ZCCHC8 EXOSC10 EXOSC1 EXOSC9 RBM7 EXOSC2 MTREX EXOSC6 EXOSC8 EXOSC7 C1D	RNA binding
GO:1901360	1.6392699489e-05	1.0	EXOSC3 HBS1L EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC5 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 C1D EXOSC7 EXOSC6	organic cyclic compound metabolic process
GO:0045006	1.68308738937e-05	0.222222222222	EXOSC3 EXOSC5 EXOSC4 EXOSC6	DNA deamination
GO:0061013	1.73452616973e-05	0.388888888889	EXOSC3 EXOSC5 EXOSC9 DIS3 EXOSC8 EXOSC2 EXOSC7	regulation of mRNA catabolic process
GO:0010467	1.75873712133e-05	1.0	EXOSC3 HBS1L EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC5 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 C1D EXOSC7 EXOSC6	gene expression
HPA:0460642	3.05937511824e-05	0.722222222222	EXOSC3 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC10 HBS1L MTREX EXOSC2 DIS3 EXOSC7 C1D	skin 1; Langerhans[>=Medium]
GO:0034641	3.61502183153e-05	1.0	EXOSC3 HBS1L EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC5 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 C1D EXOSC7 EXOSC6	cellular nitrogen compound metabolic process
HPA:0470682	4.49468399004e-05	0.833333333333	EXOSC3 EXOSC4 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC2 HBS1L MTREX DIS3 DIS3L C1D EXOSC7 EXOSC10	skin 2; epidermal cells[>=Medium]
HP:0004886	6.67498497768e-05	0.166666666667	EXOSC3 EXOSC9 EXOSC8	Congenital laryngeal stridor
GO:0009059	7.71105965449e-05	1.0	EXOSC3 HBS1L EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC5 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 C1D EXOSC7 EXOSC6	macromolecule biosynthetic process
GO:0034476	7.84339535184e-05	0.166666666667	EXOSC8 EXOSC7 EXOSC9	U5 snRNA 3'-end processing
GO:0034473	7.84339535184e-05	0.166666666667	EXOSC8 EXOSC7 EXOSC9	U1 snRNA 3'-end processing
HPA:0460672	0.000199977804641	0.777777777778	EXOSC3 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC2 HBS1L MTREX DIS3 DIS3L C1D EXOSC7 EXOSC10	skin 1; melanocytes[>=Medium]
HPA:0050092	0.000271887920189	0.777777777778	EXOSC3 EXOSC4 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC10 HBS1L MTREX EXOSC2 DIS3 EXOSC7 C1D	breast; myoepithelial cells[>=Medium]
GO:0071047	0.000313494264121	0.166666666667	EXOSC8 EXOSC7 EXOSC9	polyadenylation-dependent mRNA catabolic process
GO:0071042	0.000313494264121	0.166666666667	EXOSC8 EXOSC7 EXOSC9	nuclear polyadenylation-dependent mRNA catabolic process
GO:0016788	0.000337520174924	0.5	EXOSC3 EXOSC4 EXOSC5 EXOSC9 EXOSC2 DIS3 DIS3L EXOSC7 EXOSC10	hydrolase activity, acting on ester bonds
HPA:0460662	0.000415694717284	0.722222222222	EXOSC3 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC10 HBS1L MTREX EXOSC2 DIS3 EXOSC7 C1D	skin 1; keratinocytes[>=Medium]
HP:0005348	0.000542926757632	0.166666666667	EXOSC3 EXOSC9 EXOSC8	Inspiratory stridor
HPA:0460651	0.000556530328871	0.777777777778	EXOSC3 EXOSC4 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC2 HBS1L MTREX DIS3 DIS3L EXOSC7 C1D	skin 1; fibroblasts[>=Low]
HPA:0620222	0.000666426017857	0.777777777778	EXOSC3 EXOSC4 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC10 HBS1L MTREX EXOSC2 DIS3 EXOSC7 C1D	vagina; squamous epithelial cells[>=Medium]
HPA:0090162	0.000784869037228	0.777777777778	EXOSC3 EXOSC4 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC10 HBS1L MTREX EXOSC2 DIS3 EXOSC7 C1D	cerebellum; Purkinje cells[>=Medium]
GO:0044249	0.000790228697705	1.0	EXOSC3 HBS1L EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC5 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 C1D EXOSC7 EXOSC6	cellular biosynthetic process
GO:0005654	0.000871515982599	0.888888888889	EXOSC3 EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC5 EXOSC2 MTREX DIS3 EXOSC8 ZCCHC8 C1D EXOSC7 EXOSC6	nucleoplasm
GO:0031331	0.000908801163488	0.388888888889	EXOSC3 EXOSC5 EXOSC9 DIS3 EXOSC8 EXOSC2 EXOSC7	positive regulation of cellular catabolic process
GO:1901576	0.000914898997088	1.0	EXOSC3 HBS1L EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC5 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 C1D EXOSC7 EXOSC6	organic substance biosynthetic process
GO:0009058	0.0010203541129	1.0	EXOSC3 HBS1L EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC5 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 C1D EXOSC7 EXOSC6	biosynthetic process
HPA:0190222	0.00121574399119	0.833333333333	EXOSC3 EXOSC4 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC2 HBS1L MTREX DIS3 DIS3L C1D EXOSC7 EXOSC10	esophagus; squamous epithelial cells[>=Medium]
HPA:0460661	0.00124934639677	0.833333333333	EXOSC3 EXOSC4 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC2 HBS1L MTREX DIS3 DIS3L C1D EXOSC7 EXOSC10	skin 1; keratinocytes[>=Low]
HP:0002398	0.00154309552699	0.166666666667	EXOSC3 EXOSC9 EXOSC8	Degeneration of anterior horn cells
HP:0006802	0.00183101505694	0.166666666667	EXOSC3 EXOSC9 EXOSC8	Abnormal anterior horn cell morphology
HPA:0460671	0.00215963901866	0.833333333333	EXOSC3 EXOSC4 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC2 HBS1L MTREX DIS3 DIS3L C1D EXOSC7 EXOSC10	skin 1; melanocytes[>=Low]
GO:0031981	0.00235324229769	0.888888888889	EXOSC3 EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC5 EXOSC2 MTREX DIS3 EXOSC8 ZCCHC8 C1D EXOSC7 EXOSC6	nuclear lumen
GO:0006399	0.00246614601801	0.333333333333	EXOSC3 EXOSC10 EXOSC8 EXOSC9 EXOSC2 EXOSC7	tRNA metabolic process
HP:0012110	0.00264657296537	0.222222222222	EXOSC3 EXOSC1 EXOSC9 EXOSC8	Hypoplasia of the pons
HPA:0460641	0.00357026683852	0.722222222222	EXOSC3 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC10 HBS1L MTREX EXOSC2 DIS3 EXOSC7 C1D	skin 1; Langerhans[>=Low]
HPA:0090161	0.00389527610148	0.833333333333	EXOSC3 EXOSC4 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC2 HBS1L MTREX DIS3 DIS3L C1D EXOSC7 EXOSC10	cerebellum; Purkinje cells[>=Low]
GO:0032991	0.00435794847069	0.944444444444	EXOSC3 HBS1L EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 EXOSC5 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 C1D EXOSC7 EXOSC6	protein-containing complex
HPA:0030071	0.0044341950427	0.777777777778	EXOSC3 EXOSC4 ZCCHC8 EXOSC5 EXOSC1 EXOSC9 RBM7 EXOSC2 HBS1L MTREX DIS3 DIS3L EXOSC7 EXOSC10	appendix; lymphoid tissue[>=Low]
HPA:0470681	0.00460225107398	0.833333333333	EXOSC3 EXOSC4 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC2 HBS1L MTREX DIS3 DIS3L C1D EXOSC7 EXOSC10	skin 2; epidermal cells[>=Low]
HPA:0100131	0.00519151940949	0.888888888889	EXOSC3 EXOSC4 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC5 EXOSC2 HBS1L MTREX DIS3 DIS3L C1D EXOSC7 EXOSC10	cerebral cortex; neuronal cells[>=Low]
HPA:0050091	0.00561675265018	0.833333333333	EXOSC3 EXOSC4 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC2 HBS1L MTREX DIS3 DIS3L C1D EXOSC7 EXOSC10	breast; myoepithelial cells[>=Low]
HP:0007361	0.00659996895778	0.222222222222	EXOSC3 EXOSC1 EXOSC9 EXOSC8	Abnormal pons morphology
HPA:0460652	0.00682735201903	0.611111111111	EXOSC3 EXOSC4 ZCCHC8 HBS1L EXOSC1 EXOSC9 EXOSC2 MTREX DIS3 DIS3L C1D	skin 1; fibroblasts[>=Medium]
GO:0000791	0.0079257196095	0.222222222222	EXOSC3 EXOSC10 EXOSC4 EXOSC5	euchromatin
HP:0001308	0.00841557073161	0.166666666667	EXOSC3 EXOSC9 EXOSC8	Tongue fasciculations
GO:0010558	0.0102556939731	0.611111111111	EXOSC3 HBS1L EXOSC4 EXOSC5 EXOSC9 EXOSC2 DIS3 EXOSC8 EXOSC6 EXOSC7 EXOSC10	negative regulation of macromolecule biosynthetic process
HPA:0620221	0.0117947505188	0.833333333333	EXOSC3 EXOSC4 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC2 HBS1L MTREX DIS3 DIS3L C1D EXOSC7 EXOSC10	vagina; squamous epithelial cells[>=Low]
HPA:0620000	0.0117947505188	0.833333333333	EXOSC3 EXOSC4 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC2 HBS1L MTREX DIS3 DIS3L C1D EXOSC7 EXOSC10	vagina
HPA:0050052	0.0118068976667	0.777777777778	EXOSC3 EXOSC4 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC10 HBS1L MTREX EXOSC2 DIS3 EXOSC7 C1D	breast; glandular cells[>=Medium]
GO:0010608	0.0122904059214	0.388888888889	EXOSC3 EXOSC5 EXOSC9 DIS3 EXOSC8 EXOSC2 EXOSC7	post-transcriptional regulation of gene expression
WP:WP4352	0.0125585215046	0.222222222222	EXOSC2 EXOSC7 EXOSC9 EXOSC4	Ciliary landscape
GO:0031327	0.0129221723315	0.611111111111	EXOSC3 HBS1L EXOSC4 EXOSC5 EXOSC9 EXOSC2 DIS3 EXOSC8 EXOSC6 EXOSC7 EXOSC10	negative regulation of cellular biosynthetic process
HPA:0470683	0.013434475854	0.388888888889	EXOSC3 EXOSC10 EXOSC9 MTREX ZCCHC8 EXOSC2 MPHOSPH6	skin 2; epidermal cells[High]
GO:0009890	0.0137246478108	0.611111111111	EXOSC3 HBS1L EXOSC4 EXOSC5 EXOSC9 EXOSC2 DIS3 EXOSC8 EXOSC6 EXOSC7 EXOSC10	negative regulation of biosynthetic process
HP:0010307	0.0183696141885	0.166666666667	EXOSC3 EXOSC9 EXOSC8	Stridor
HPA:0570732	0.0191651021509	0.777777777778	EXOSC3 EXOSC4 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC2 HBS1L MTREX DIS3 DIS3L C1D EXOSC10	testis; Leydig cells[>=Medium]
GO:0009896	0.0192389037494	0.388888888889	EXOSC3 EXOSC5 EXOSC9 DIS3 EXOSC8 EXOSC2 EXOSC7	positive regulation of catabolic process
HPA:0500000	0.019363157111	0.777777777778	EXOSC3 EXOSC4 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC2 HBS1L MTREX DIS3 DIS3L EXOSC7 C1D	soft tissue 1
HPA:0241101	0.0195311745161	0.833333333333	EXOSC4 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC5 EXOSC2 HBS1L MTREX DIS3L DIS3 C1D EXOSC7 EXOSC10	heart muscle; cardiomyocytes[>=Low]
HPA:0240000	0.0195311745161	0.833333333333	EXOSC4 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC5 EXOSC2 HBS1L MTREX DIS3L DIS3 C1D EXOSC7 EXOSC10	heart muscle
HPA:0550052	0.0205850357082	0.833333333333	EXOSC3 EXOSC4 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC2 HBS1L MTREX DIS3 DIS3L C1D EXOSC7 EXOSC10	stomach 2; glandular cells[>=Medium]
GO:0043170	0.0218804672791	1.0	EXOSC3 HBS1L EXOSC4 EXOSC10 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC5 EXOSC2 DIS3 MTREX EXOSC8 DIS3L ZCCHC8 C1D EXOSC7 EXOSC6	macromolecule metabolic process
HPA:0340000	0.023792249411	0.777777777778	EXOSC3 EXOSC4 MPHOSPH6 ZCCHC8 EXOSC9 RBM7 EXOSC5 EXOSC2 HBS1L MTREX DIS3 DIS3L EXOSC7 EXOSC10	ovary
HPA:0490000	0.0240329177873	0.777777777778	EXOSC3 EXOSC4 ZCCHC8 EXOSC10 EXOSC1 EXOSC9 RBM7 EXOSC2 HBS1L MTREX DIS3 DIS3L EXOSC7 C1D	smooth muscle
HPA:0490691	0.0240329177873	0.777777777778	EXOSC3 EXOSC4 ZCCHC8 EXOSC10 EXOSC1 EXOSC9 RBM7 EXOSC2 HBS1L MTREX DIS3 DIS3L EXOSC7 C1D	smooth muscle; smooth muscle cells[>=Low]
HPA:0620223	0.0240386754493	0.388888888889	EXOSC3 RBM7 EXOSC9 EXOSC10 MTREX HBS1L ZCCHC8	vagina; squamous epithelial cells[High]
HPA:0100201	0.0244227505724	0.722222222222	EXOSC3 EXOSC4 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 HBS1L MTREX EXOSC2 DIS3 EXOSC7 C1D	cerebral cortex; endothelial cells[>=Low]
HPA:0330223	0.0282571840891	0.388888888889	EXOSC3 HBS1L MPHOSPH6 DIS3 MTREX EXOSC10 ZCCHC8	oral mucosa; squamous epithelial cells[High]
GO:0006304	0.0305373630844	0.222222222222	EXOSC3 EXOSC5 EXOSC4 EXOSC6	DNA modification
HP:0002120	0.0320166605612	0.277777777778	EXOSC3 EXOSC5 EXOSC9 EXOSC2 EXOSC8	Cerebral cortical atrophy
HP:0030810	0.0361621092544	0.166666666667	EXOSC3 EXOSC9 EXOSC8	Abnormal tongue physiology
HPA:0130201	0.0361779324088	0.777777777778	EXOSC3 EXOSC4 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC2 HBS1L MTREX DIS3 DIS3L EXOSC7 C1D	colon; endothelial cells[>=Low]
HPA:0590052	0.0367053925786	0.777777777778	EXOSC3 EXOSC4 ZCCHC8 EXOSC10 EXOSC1 EXOSC9 RBM7 EXOSC2 HBS1L MTREX DIS3 DIS3L EXOSC7 C1D	thyroid gland; glandular cells[>=Medium]
HPA:0510651	0.0453089047952	0.666666666667	EXOSC3 EXOSC4 ZCCHC8 RBM7 EXOSC1 EXOSC9 EXOSC2 HBS1L MTREX DIS3 DIS3L EXOSC7	soft tissue 2; fibroblasts[>=Low]
HPA:0190000	0.0460006119896	0.833333333333	EXOSC3 EXOSC4 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC2 HBS1L MTREX DIS3 DIS3L C1D EXOSC7 EXOSC10	esophagus
HPA:0190221	0.0460006119896	0.833333333333	EXOSC3 EXOSC4 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC2 HBS1L MTREX DIS3 DIS3L C1D EXOSC7 EXOSC10	esophagus; squamous epithelial cells[>=Low]
HPA:0170051	0.047552030999	0.833333333333	EXOSC3 EXOSC4 ZCCHC8 MPHOSPH6 EXOSC1 EXOSC9 RBM7 EXOSC2 HBS1L MTREX DIS3 DIS3L C1D EXOSC7 EXOSC10	endometrium 2; glandular cells[>=Low]
HP:0000565	0.0480869650528	0.222222222222	EXOSC3 EXOSC5 EXOSC9 EXOSC8	Esotropia
HP:0010546	0.0482176471165	0.166666666667	EXOSC3 EXOSC9 EXOSC8	Muscle fibrillation
CORUM:2004	0.0496617483143	0.0555555555556	C1D	C1D homodimer protein



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?
EXOSC6	EXOSC2	1.0	0.946
EXOSC5	EXOSC2	1.0	0.972
EXOSC1	EXOSC2	1.0	0.944
EXOSC7	EXOSC10	1.0	0.906
EXOSC1	EXOSC4	1.0	0.842
EXOSC7	MPHOSPH6	1.0	0.208
EXOSC4	EXOSC6	1.0	0.764
EXOSC1	MPHOSPH6	1.0	0.416
EXOSC2	EXOSC10	1.0	0.894
EXOSC4	EXOSC2	1.0	0.97
MPHOSPH6	EXOSC5	1.0	0.236
MPHOSPH6	EXOSC2	1.0	0.166
EXOSC4	EXOSC5	1.0	0.966
EXOSC8	MPHOSPH6	1.0	0.136
EXOSC2	EXOSC9	1.0	0.992
EXOSC3	MPHOSPH6	1.0	0.246
EXOSC4	EXOSC10	1.0	0.786
MPHOSPH6	EXOSC6	1.0	0.322
MPHOSPH6	EXOSC9	1.0	0.132
EXOSC3	EXOSC10	1.0	0.952
EXOSC1	EXOSC9	1.0	0.978
EXOSC8	EXOSC10	1.0	0.856
EXOSC3	EXOSC7	1.0	0.982
EXOSC5	EXOSC10	1.0	0.884
EXOSC2	C1D	1.0	0.356
EXOSC4	MPHOSPH6	1.0	0.426
EXOSC6	EXOSC5	1.0	0.634
EXOSC3	EXOSC6	1.0	0.946
EXOSC8	EXOSC2	1.0	0.902
MTREX	C1D	1.0	0.334
EXOSC4	C1D	1.0	0.438
EXOSC1	C1D	1.0	0.528
EXOSC3	EXOSC9	1.0	0.994
MPHOSPH6	EXOSC10	1.0	0.27
EXOSC3	EXOSC2	1.0	0.982
EXOSC1	EXOSC10	1.0	0.844
EXOSC3	EXOSC5	1.0	0.982
EXOSC6	C1D	1.0	0.256
EXOSC1	EXOSC5	1.0	0.962
EXOSC4	EXOSC9	1.0	0.97
EXOSC5	EXOSC9	1.0	0.982
EXOSC1	EXOSC7	1.0	0.932
EXOSC10	C1D	1.0	0.424
C1D	EXOSC9	1.0	0.3
EXOSC7	EXOSC2	1.0	0.988
MPHOSPH6	C1D	1.0	0.314
EXOSC7	EXOSC4	1.0	0.974
MTREX	EXOSC2	1.0	0.81
EXOSC5	C1D	1.0	0.366
EXOSC7	EXOSC5	1.0	0.95
EXOSC1	DIS3L	1.0	0.136
EXOSC3	C1D	1.0	0.546
MTREX	MPHOSPH6	1.0	0.128
DIS3L	EXOSC4	1.0	0.23
EXOSC10	EXOSC9	1.0	0.95
EXOSC8	EXOSC5	1.0	0.712
RBM7	C1D	1.0	0.174
EXOSC3	EXOSC4	1.0	0.974
EXOSC1	EXOSC3	1.0	0.966
EXOSC6	EXOSC9	1.0	0.688
EXOSC6	EXOSC10	1.0	0.836
ZCCHC8	C1D	1.0	0.13
EXOSC1	EXOSC8	1.0	0.884
ZCCHC8	RBM7	1.0	0.234
EXOSC1	EXOSC6	1.0	0.928
DIS3L	EXOSC2	1.0	0.132
EXOSC7	C1D	1.0	0.501428571429
DIS3L	EXOSC5	1.0	0.17
EXOSC7	EXOSC9	1.0	0.982
EXOSC7	DIS3L	1.0	0.108
EXOSC3	DIS3L	1.0	0.202
EXOSC3	HBS1L	1.0	0.092
EXOSC7	EXOSC6	0.999	0.788
MTREX	RBM7	0.999	0.47
EXOSC3	MTREX	0.999	0.746
EXOSC8	EXOSC4	0.999	0.778
DIS3L	MPHOSPH6	0.999	0.09
EXOSC3	EXOSC8	0.999	0.856
MTREX	EXOSC5	0.999	0.576
EXOSC3	ZCCHC8	0.999	0.192
EXOSC7	EXOSC8	0.999	0.944
EXOSC4	ZCCHC8	0.999	0.156
EXOSC7	MTREX	0.999	0.79
EXOSC1	HBS1L	0.999	0.084
EXOSC8	EXOSC9	0.999	0.934
MTREX	EXOSC4	0.999	0.588
DIS3L	C1D	0.999	0.132
EXOSC7	HBS1L	0.999	0.1
EXOSC8	EXOSC6	0.999	0.706
EXOSC7	ZCCHC8	0.999	0.154
DIS3L	EXOSC9	0.999	0.186
EXOSC8	C1D	0.998	0.56
MTREX	EXOSC8	0.998	0.66
EXOSC5	RBM7	0.998	0.264
EXOSC4	HBS1L	0.998	0.126
EXOSC7	RBM7	0.998	0.154
MPHOSPH6	RBM7	0.998	0.062
MTREX	ZCCHC8	0.998	0.266
MTREX	EXOSC6	0.998	0.472
EXOSC4	RBM7	0.998	0.23
EXOSC10	RBM7	0.998	0.176
DIS3	C1D	0.998	0.256
MPHOSPH6	ZCCHC8	0.998	0.1
EXOSC1	MTREX	0.997	0.636
EXOSC2	ZCCHC8	0.997	0.272
EXOSC8	RBM7	0.997	0.12
MTREX	DIS3L	0.997	0.13
EXOSC2	RBM7	0.997	0.128
EXOSC5	ZCCHC8	0.997	0.278
EXOSC2	HBS1L	0.996	0.102
EXOSC1	RBM7	0.996	0.122
DIS3	MPHOSPH6	0.996	0.178
MTREX	EXOSC10	0.996	0.832
EXOSC3	RBM7	0.996	0.222
EXOSC5	HBS1L	0.996	0.064
DIS3L	EXOSC6	0.996	0.13
DIS3L	EXOSC8	0.996	0.126
MTREX	EXOSC9	0.995	0.824
DIS3L	EXOSC10	0.995	0.184
EXOSC8	ZCCHC8	0.994	0.27
EXOSC10	ZCCHC8	0.994	0.176
C1D	HBS1L	0.991	0.084
EXOSC8	HBS1L	0.991	0.05
EXOSC1	ZCCHC8	0.988	0.17
DIS3L	HBS1L	0.987	0.13
DIS3	EXOSC5	0.986	0.37
DIS3L	ZCCHC8	0.985	0.09
DIS3L	RBM7	0.985	0.06
DIS3	EXOSC4	0.977	0.322
RBM7	EXOSC9	0.977	0.088
DIS3	EXOSC7	0.968	0.24
MPHOSPH6	HBS1L	0.962	0.14
EXOSC6	ZCCHC8	0.96	0.194
DIS3	EXOSC3	0.955	0.19
ZCCHC8	EXOSC9	0.954	0.226
EXOSC10	HBS1L	0.944	0.052
MTREX	HBS1L	0.943	0.118
EXOSC6	HBS1L	0.942	0.09
RBM7	HBS1L	0.932	0.046
DIS3	EXOSC10	0.929	0.446
EXOSC6	RBM7	0.91	0.114
HBS1L	EXOSC9	0.9	0.112
DIS3	EXOSC2	0.896	0.446
ZCCHC8	HBS1L	0.817	0.058
DIS3	EXOSC1	0.616	0.188
DIS3	EXOSC9	0.352	0.426
DIS3	DIS3L	0.332	0.084
DIS3	EXOSC6	0.33	0.252
DIS3	EXOSC8	0.254	0.264
DIS3	RBM7	0.162	0.112
DIS3	HBS1L	0.043	0.12
DIS3	MTREX	0.041	0.464
DIS3	ZCCHC8	0.03	0.238





Related Complexes

Genename	Complexes
EXOSC3	huMAP3_05382.1 huMAP3_14264.1
DIS3	huMAP3_01165.1 huMAP3_05382.1 huMAP3_10791.1
EXOSC7	huMAP3_05382.1 huMAP3_14264.1
MTREX	huMAP3_05382.1 huMAP3_14264.1
DIS3L	huMAP3_05382.1 huMAP3_14264.1
EXOSC8	huMAP3_05382.1 huMAP3_14264.1
EXOSC4	huMAP3_05382.1 huMAP3_14264.1
EXOSC1	huMAP3_05194.1 huMAP3_05382.1 huMAP3_14264.1
MPHOSPH6	huMAP3_05382.1 huMAP3_14264.1
EXOSC6	huMAP3_05382.1 huMAP3_14264.1
EXOSC5	huMAP3_05382.1 huMAP3_14264.1
EXOSC2	huMAP3_05382.1 huMAP3_14264.1
EXOSC10	huMAP3_05382.1
ZCCHC8	huMAP3_05382.1 huMAP3_14264.1
RBM7	huMAP3_05382.1 huMAP3_13336.1
C1D	huMAP3_05382.1 huMAP3_14264.1
HBS1L	huMAP3_05382.1 huMAP3_14264.1
EXOSC9	huMAP3_05382.1 huMAP3_14264.1