hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_05394.1
Complex Portal: CPX-24311
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MFSD9 | Major facilitator superfamily domain-containing protein 9 | 2 | UniProt NCBI |
| TMEM143 | Transmembrane protein 143 | 5 | UniProt NCBI |
| CCDC126 | Coiled-coil domain-containing protein 126 | 2 | UniProt NCBI |
| NIPAL1 | Magnesium transporter NIPA3 (NIPA-like protein 1) (Non-imprinted in Prader-Willi/Angelman syndrome region protein 3) | 3 | UniProt NCBI |
| TMEM248 | Transmembrane protein 248 | 5 | UniProt NCBI |
| NIPA2 | Magnesium transporter NIPA2 (Non-imprinted in Prader-Willi/Angelman syndrome region protein 2) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5223345 | 0.00488968644054 | 0.333333333333 | NIPAL1 NIPA2 | Miscellaneous transport and binding events |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| NIPA2 | NIPAL1 | 0.988 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM WMM_only | |
| MFSD9 | NIPAL1 | 0.982 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM WMM_only | |
| TMEM143 | NIPAL1 | 0.974 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| CCDC126 | NIPAL1 | 0.971 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex3_WMM WMM_only | |
| TMEM248 | NIPAL1 | 0.969 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| CCDC126 | TMEM248 | 0.415 | 0.084 | bioplex3_WMM WMM_only | |
| NIPA2 | TMEM248 | 0.278 | 0.092 | bioplex3_WMM WMM_only | |
| MFSD9 | TMEM248 | 0.25 | bioplex3_WMM WMM_only | ||
| NIPA2 | CCDC126 | 0.25 | 0.066 |
mutually_exclusive (Q6NVV3)
|
bioplex3_WMM WMM_only |
| CCDC126 | MFSD9 | 0.113 |
structurally_consistent (Q6NVV3)
|
bioplex3_WMM WMM_only | |
| TMEM143 | TMEM248 | 0.095 | bioplex3_WMM WMM_only | ||
| NIPA2 | TMEM143 | 0.089 | bioplex3_WMM WMM_only | ||
| TMEM143 | MFSD9 | 0.079 | bioplex3_WMM WMM_only | ||
| NIPA2 | MFSD9 | 0.078 | bioplex3_WMM WMM_only | ||
| TMEM143 | CCDC126 | 0.076 | bioplex3_WMM WMM_only |
Related Complexes