hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_05430.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CTC1 | CST complex subunit CTC1 (Conserved telomere maintenance component 1) (HBV DNAPTP1-transactivated protein B) | 5 | UniProt NCBI |
| STN1 | CST complex subunit STN1 (Oligonucleotide/oligosaccharide-binding fold-containing protein 1) (Suppressor of cdc thirteen homolog) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6075 | 5.12628525639e-06 | 1.0 | CTC1 STN1 | CST complex |
| REAC:R-HSA-174430 | 0.000133283416666 | 1.0 | CTC1 STN1 | Telomere C-strand synthesis initiation |
| REAC:R-HSA-174411 | 0.000555347569442 | 1.0 | CTC1 STN1 | Polymerase switching on the C-strand of the telomere |
| HP:0007763 | 0.000943236487175 | 1.0 | CTC1 STN1 | Retinal telangiectasia |
| REAC:R-HSA-174417 | 0.000958615342944 | 1.0 | CTC1 STN1 | Telomere C-strand (Lagging Strand) Synthesis |
| GO:1990879 | 0.00140460216025 | 1.0 | CTC1 STN1 | CST complex |
| REAC:R-HSA-180786 | 0.00217867123396 | 1.0 | CTC1 STN1 | Extension of Telomeres |
| HP:0002216 | 0.00308602372434 | 1.0 | CTC1 STN1 | Premature graying of hair |
| HP:0005528 | 0.00604901660254 | 1.0 | CTC1 STN1 | Bone marrow hypocellularity |
| HP:0002206 | 0.0077851185427 | 1.0 | CTC1 STN1 | Pulmonary fibrosis |
| REAC:R-HSA-157579 | 0.00845837067304 | 1.0 | CTC1 STN1 | Telomere Maintenance |
| REAC:R-HSA-73886 | 0.0136718027788 | 1.0 | CTC1 STN1 | Chromosome Maintenance |
| HP:0009887 | 0.0172584936965 | 1.0 | CTC1 STN1 | Abnormality of hair pigmentation |
| HP:0006530 | 0.026912997596 | 1.0 | CTC1 STN1 | Abnormal pulmonary interstitial morphology |
| GO:0043047 | 0.0309012475255 | 1.0 | CTC1 STN1 | single-stranded telomeric DNA binding |
| GO:0000783 | 0.0309012475255 | 1.0 | CTC1 STN1 | nuclear telomere cap complex |
| GO:0000782 | 0.0309012475255 | 1.0 | CTC1 STN1 | telomere cap complex |
| GO:0098847 | 0.0309012475255 | 1.0 | CTC1 STN1 | sequence-specific single stranded DNA binding |
| HP:0002239 | 0.0318376489657 | 1.0 | CTC1 STN1 | Gastrointestinal hemorrhage |
| HP:0001009 | 0.0351868219998 | 1.0 | CTC1 STN1 | Telangiectasia |
| GO:0140445 | 0.0365196561665 | 1.0 | CTC1 STN1 | chromosome, telomeric repeat region |
| HP:0007495 | 0.0397389633075 | 1.0 | CTC1 STN1 | Prematurely aged appearance |
| HP:0012145 | 0.0397389633075 | 1.0 | CTC1 STN1 | Abnormality of multiple cell lineages in the bone marrow |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| STN1 | CTC1 | 0.998 | 0.082 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes
| Genename | Complexes |
|---|---|
| CTC1 | huMAP3_05430.1 huMAP3_05946.1 huMAP3_08768.1 huMAP3_09250.1 huMAP3_14608.1 |
| STN1 | huMAP3_01570.1 huMAP3_05430.1 huMAP3_09250.1 huMAP3_14608.1 |