hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05445.1
Complex Portal: CPX-18653
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FADS2 | Acyl-CoA 6-desaturase (EC 1.14.19.3) (Delta(6) fatty acid desaturase) (D6D) (Delta(6) desaturase) (Delta-6 desaturase) (Fatty acid desaturase 2) | 5 | UniProt NCBI |
| FADS3 | Fatty acid desaturase 3 (FADS3) (EC 1.14.19.-) (Delta(13) fatty acid desaturase) (Delta(13) desaturase) | 5 | UniProt NCBI |
| ERICH5 | Glutamate-rich protein 5 | 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0016717 | 0.0294899169624 | 0.666666666667 | FADS2 FADS3 | oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water |
| WP:WP4586 | 0.0413734636003 | 0.333333333333 | FADS2 | Metabolism of alpha linolenic acid |
| WP:WP5315 | 0.0413734636003 | 0.333333333333 | FADS2 | Sebaleic acid formation and metabolism |
| WP:WP4853 | 0.0496447587094 | 0.333333333333 | FADS2 | Linoleic acid metabolism affected by SARS CoV 2 |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ERICH5 | FADS3 | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| FADS2 | FADS3 | 0.976 | 0.042 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ERICH5 | FADS2 | 0.018 | 0.088 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes