hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05447.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GINS2 | DNA replication complex GINS protein PSF2 (GINS complex subunit 2) | 5 | UniProt NCBI |
| GINS3 | DNA replication complex GINS protein PSF3 (GINS complex subunit 3) | 5 | UniProt NCBI |
| GINS1 | DNA replication complex GINS protein PSF1 (GINS complex subunit 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:678 | 9.35474852325e-10 | 1.0 | GINS1 GINS2 GINS3 | GINS complex |
| REAC:R-HSA-176974 | 1.02652471053e-07 | 1.0 | GINS1 GINS2 GINS3 | Unwinding of DNA |
| GO:0000811 | 3.84480164306e-07 | 1.0 | GINS1 GINS2 GINS3 | GINS complex |
| REAC:R-HSA-69190 | 2.31434662009e-06 | 1.0 | GINS1 GINS2 GINS3 | DNA strand elongation |
| GO:0071162 | 1.58598067776e-05 | 1.0 | GINS1 GINS2 GINS3 | CMG complex |
| GO:0031261 | 2.11464090368e-05 | 1.0 | GINS1 GINS2 GINS3 | DNA replication preinitiation complex |
| REAC:R-HSA-69239 | 0.000127764531687 | 1.0 | GINS1 GINS2 GINS3 | Synthesis of DNA |
| GO:0006268 | 0.000127839654632 | 1.0 | GINS1 GINS2 GINS3 | DNA unwinding involved in DNA replication |
| REAC:R-HSA-69242 | 0.000306725116903 | 1.0 | GINS1 GINS2 GINS3 | S Phase |
| REAC:R-HSA-69306 | 0.000402642186048 | 1.0 | GINS1 GINS2 GINS3 | DNA Replication |
| GO:0032508 | 0.00136394338287 | 1.0 | GINS1 GINS2 GINS3 | DNA duplex unwinding |
| GO:0032392 | 0.00225170808226 | 1.0 | GINS1 GINS2 GINS3 | DNA geometric change |
| GO:0071103 | 0.00328922780564 | 1.0 | GINS1 GINS2 GINS3 | DNA conformation change |
| REAC:R-HSA-69278 | 0.0112530904983 | 1.0 | GINS1 GINS2 GINS3 | Cell Cycle, Mitotic |
| REAC:R-HSA-1640170 | 0.0209648611427 | 1.0 | GINS1 GINS2 GINS3 | Cell Cycle |
| GO:0006261 | 0.0439566559847 | 1.0 | GINS1 GINS2 GINS3 | DNA-templated DNA replication |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| GINS3 | GINS1 | 1.0 | 0.93 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM Malo bioplex3_HCT116 fraction |
| GINS2 | GINS1 | 1.0 | 0.838 |
structurally_consistent (O75419)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM Malo bioplex3_HCT116 fraction |
| GINS2 | GINS3 | 1.0 | 0.908 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM Malo bioplex3_HCT116 fraction |
Related Complexes