hu.MAP 3.0: Complex View

Genename	Protein Name	Uniprot Annotation Score	Links
TXNRD2	Thioredoxin reductase 2, mitochondrial (EC 1.8.1.9) (Selenoprotein Z) (SelZ) (TR-beta) (Thioredoxin reductase TR3)	5	UniProt NCBI
TXNRD1	Thioredoxin reductase 1, cytoplasmic (TR) (EC 1.8.1.9) (Gene associated with retinoic and interferon-induced mortality 12 protein) (GRIM-12) (Gene associated with retinoic and IFN-induced mortality 12 protein) (KM-102-derived reductase-like factor) (Peroxidase TXNRD1) (EC 1.11.1.2) (Thioredoxin reductase TR1)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
KEGG:00450	1.26804361689e-05	1.0	TXNRD2 TXNRD1	Selenocompound metabolism
WP:WP408	0.000160890792901	1.0	TXNRD2 TXNRD1	Oxidative stress response
REAC:R-HSA-3299685	0.000645911942305	1.0	TXNRD2 TXNRD1	Detoxification of Reactive Oxygen Species
WP:WP15	0.000969601127591	1.0	TXNRD2 TXNRD1	Selenium micronutrient network
KEGG:05225	0.00204203793228	1.0	TXNRD2 TXNRD1	Hepatocellular carcinoma
GO:0004791	0.00983221512175	1.0	TXNRD2 TXNRD1	thioredoxin-disulfide reductase (NADP) activity
KEGG:05200	0.0161326036311	1.0	TXNRD2 TXNRD1	Pathways in cancer
GO:0047134	0.016855225923	1.0	TXNRD2 TXNRD1	protein-disulfide reductase (NAD(P)) activity
REAC:R-HSA-5263617	0.0249718442457	0.5	TXNRD1	Metabolism of ingested MeSeO2H into MeSeH
REAC:R-HSA-9711123	0.0284560094582	1.0	TXNRD2 TXNRD1	Cellular response to chemical stress
GO:0016668	0.0309012475255	1.0	TXNRD2 TXNRD1	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor

Protein 1	Protein 2	Score	ProteomeHD	Evidence
TXNRD2	TXNRD1	0.995	0.078	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM

Genename	Complexes
TXNRD2	huMAP3_02075.1 huMAP3_05449.1 huMAP3_10055.1 huMAP3_10680.1 huMAP3_12151.1
TXNRD1	huMAP3_02075.1 huMAP3_04662.1 huMAP3_05449.1 huMAP3_05902.1 huMAP3_10055.1 huMAP3_10680.1 huMAP3_11117.1 huMAP3_12151.1 huMAP3_12974.1