hu.MAP 3.0: Complex View

Genename	Protein Name	Uniprot Annotation Score	Links
SKIL	Ski-like protein (Ski-related oncogene) (Ski-related protein)	5	UniProt NCBI
SMAD4	Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (SMAD family member 4) (SMAD 4) (Smad4) (hSMAD4)	5	UniProt NCBI
SKI	Ski oncogene (Proto-oncogene c-Ski)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:3197	0.0249718442455	1.0	SMAD4	SMAD4-SNO-SKI complex
CORUM:3200	0.0249718442455	1.0	SMAD4	SMAD4-SKI complex
REAC:R-HSA-3304347	0.0374577663684	1.0	SMAD4	Loss of Function of SMAD4 in Cancer
REAC:R-HSA-3315487	0.0374577663684	1.0	SMAD4	SMAD2/3 MH2 Domain Mutants in Cancer
REAC:R-HSA-3311021	0.0374577663684	1.0	SMAD4	SMAD4 MH2 Domain Mutants in Cancer
WP:WP1425	0.0454335014827	1.0	SMAD4	Bone morphogenic protein signaling and regulation
HP:0004621	0.0495817777049	1.0	SMAD4	Enlarged vertebral pedicles
HP:0030277	0.0495817777049	1.0	SMAD4	Abnormal vertebral pedicle morphology
CORUM:2704	0.0499436884912	1.0	SMAD4	Ectodermin-SMAD4 complex
CORUM:3038	0.0499436884912	1.0	SMAD4	SMAD2-SMAD4-FAST1 complex
CORUM:3206	0.0499436884912	1.0	SMAD4	SMAD4-SKI-NCOR complex
CORUM:3739	0.0499436884912	1.0	SMAD4	SKI-SMAD2-SMAD4 pentameric complex
CORUM:3740	0.0499436884912	1.0	SMAD4	SKI-SMAD3-SMAD4 complex
CORUM:3959	0.0499436884912	1.0	SMAD4	SKI-SMAD3-SMAD4 complex, TGF(beta)-dependent

Protein 1	Protein 2	Score	ProteomeHD	Evidence
SKIL	SMAD4	0.998		bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
SKI	SMAD4	0.996	0.124	bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
SKI	SKIL	0.972		bioplex3_HEK293 bioplex3_WMM WMM_only

Genename	Complexes
SKIL	huMAP3_05458.1 huMAP3_11563.1 huMAP3_12145.1 huMAP3_12636.1 huMAP3_12981.1 huMAP3_13984.1
SMAD4	huMAP3_05458.1 huMAP3_12636.1 huMAP3_13984.1
SKI	huMAP3_03100.1 huMAP3_05458.1 huMAP3_05775.1 huMAP3_08787.1 huMAP3_09818.1 huMAP3_10711.1 huMAP3_12636.1 huMAP3_12700.1 huMAP3_13984.1