hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05474.1
Complex Portal: CPX-12894
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RFPL4A | Ret finger protein-like 4A (RING finger protein 210) | 4 | UniProt NCBI |
| FAM90A1 | Protein FAM90A1 | 5 | UniProt NCBI |
| BRD3 | Bromodomain-containing protein 3 (RING3-like protein) | 5 | UniProt NCBI |
| FAM90A26 | Putative protein FAM90A26 | 2 | UniProt NCBI |
| BRD2 | Bromodomain-containing protein 2 (O27.1.1) | 5 | UniProt NCBI |
| BRD4 | Bromodomain-containing protein 4 (Protein HUNK1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0070577 | 0.00339409783315 | 0.5 | BRD3 BRD2 BRD4 | lysine-acetylated histone binding |
| GO:0140033 | 0.00339409783315 | 0.5 | BRD3 BRD2 BRD4 | acetylation-dependent protein binding |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| BRD3 | BRD2 | 0.999 | 0.162 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM fraction | |
| FAM90A1 | BRD4 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| BRD4 | BRD3 | 0.997 | 0.316 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction | |
| FAM90A1 | BRD3 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| FAM90A1 | BRD2 | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| FAM90A1 | RFPL4A | 0.994 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| BRD4 | BRD2 | 0.989 | 0.294 | bioplex_WMM bioplex3_WMM youn_WMM fraction | |
| RFPL4A | BRD3 | 0.377 | bioplex_WMM bioplex3_WMM WMM_only | ||
| BRD4 | RFPL4A | 0.224 | bioplex_WMM bioplex3_WMM WMM_only | ||
| RFPL4A | BRD2 | 0.188 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes