hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05555.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SLC26A2 | Sulfate transporter (Diastrophic dysplasia protein) (Solute carrier family 26 member 2) | 5 | UniProt NCBI |
| SLC12A7 | Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4) | 5 | UniProt NCBI |
| PTPRJ | Receptor-type tyrosine-protein phosphatase eta (Protein-tyrosine phosphatase eta) (R-PTP-eta) (EC 3.1.3.48) (Density-enhanced phosphatase 1) (DEP-1) (HPTP eta) (Protein-tyrosine phosphatase receptor type J) (R-PTP-J) (CD antigen CD148) | 5 | UniProt NCBI |
| ALCAM | CD166 antigen (Activated leukocyte cell adhesion molecule) (CD antigen CD166) | 5 | UniProt NCBI |
| CSF3 | Granulocyte colony-stimulating factor (G-CSF) (Pluripoietin) (Filgrastim) (Lenograstim) | 5 | UniProt NCBI |
| LGALS3 | Galectin-3 (Gal-3) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Galactose-specific lectin 3) (Galactoside-binding protein) (GALBP) (IgE-binding protein) (L-31) (Laminin-binding protein) (Lectin L-29) (Mac-2 antigen) | 5 | UniProt NCBI |
| CD276 | CD276 antigen (4Ig-B7-H3) (B7 homolog 3) (B7-H3) (Costimulatory molecule) (CD antigen CD276) | 5 | UniProt NCBI |
| LNPEP | Leucyl-cystinyl aminopeptidase (Cystinyl aminopeptidase) (EC 3.4.11.3) (Insulin-regulated membrane aminopeptidase) (Insulin-responsive aminopeptidase) (IRAP) (Oxytocinase) (OTase) (Placental leucine aminopeptidase) (P-LAP) [Cleaved into: Leucyl-cystinyl aminopeptidase, pregnancy serum form] | 5 | UniProt NCBI |
| PTGFRN | Prostaglandin F2 receptor negative regulator (CD9 partner 1) (CD9P-1) (Glu-Trp-Ile EWI motif-containing protein F) (EWI-F) (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD antigen CD315) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5078 | 0.0151103173393 | 0.222222222222 | LGALS3 CD276 | T cell modulation in pancreatic cancer |
| GO:0001772 | 0.0325091721374 | 0.333333333333 | PTPRJ LGALS3 ALCAM | immunological synapse |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SLC26A2 | LGALS3 | 0.999 | 0.14 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| LGALS3 | PTPRJ | 0.998 | 0.226 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| LGALS3 | LNPEP | 0.996 | 0.128 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| LGALS3 | SLC12A7 | 0.996 | 0.068 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| PTPRJ | ALCAM | 0.989 | 0.152 | bioplex_WMM bioplex3_WMM WMM_only |
| LGALS3 | ALCAM | 0.989 | 0.112 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| PTPRJ | CSF3 | 0.985 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| PTPRJ | SLC12A7 | 0.977 | 0.084 | bioplex_WMM bioplex3_WMM WMM_only |
| PTPRJ | LNPEP | 0.971 | 0.118 | bioplex_WMM bioplex3_WMM WMM_only |
| CD276 | PTPRJ | 0.966 | 0.09 | bioplex_WMM bioplex3_WMM WMM_only |
| LGALS3 | PTGFRN | 0.966 | 0.0922222222222 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| PTPRJ | PTGFRN | 0.963 | 0.088 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC26A2 | ALCAM | 0.96 | 0.09 | bioplex_WMM bioplex3_WMM WMM_only |
| ALCAM | PTGFRN | 0.956 | 0.078 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC26A2 | PTPRJ | 0.952 | 0.102 | bioplex_WMM bioplex3_WMM WMM_only |
| ALCAM | SLC12A7 | 0.948 | 0.128 | bioplex_WMM bioplex3_WMM WMM_only |
| PTGFRN | LNPEP | 0.945 | 0.12 | bioplex_WMM bioplex3_WMM WMM_only |
| CD276 | LNPEP | 0.939 | 0.038 | bioplex_WMM bioplex3_WMM WMM_only |
| ALCAM | LNPEP | 0.933 | 0.082 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC26A2 | SLC12A7 | 0.912 | 0.058 | bioplex_WMM bioplex3_WMM WMM_only |
| LNPEP | SLC12A7 | 0.845 | 0.0322 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| CD276 | ALCAM | 0.706 | 0.106 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM |
| CD276 | PTGFRN | 0.667 | 0.194 | bioplex_WMM bioplex3_WMM WMM_only |
| LGALS3 | CD276 | 0.624 | 0.08 | bioplex_WMM bioplex3_WMM WMM_only |
| CD276 | SLC12A7 | 0.595 | 0.05 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC26A2 | PTGFRN | 0.344 | 0.042 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC26A2 | LNPEP | 0.319 | 0.1 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| PTGFRN | SLC12A7 | 0.254 | 0.04 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC26A2 | CD276 | 0.09 | 0.108 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes