hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_05569.1
Complex Portal: CPX-12929
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SLC35F5 | Solute carrier family 35 member F5 (Hepatitis C virus NS5A-transactivated protein 3) (HCV NS5A-transactivated protein 3) | 3 | UniProt NCBI |
| NUS1 | Dehydrodolichyl diphosphate synthase complex subunit NUS1 (EC 2.5.1.87) (Cis-prenyltransferase subunit NgBR) (Nogo-B receptor) (NgBR) (Nuclear undecaprenyl pyrophosphate synthase 1 homolog) | 5 | UniProt NCBI |
| SPINT2 | Kunitz-type protease inhibitor 2 (Hepatocyte growth factor activator inhibitor type 2) (HAI-2) (Placental bikunin) | 5 | UniProt NCBI |
| ABCA3 | Phospholipid-transporting ATPase ABCA3 (EC 7.6.2.1) (ABC-C transporter) (ATP-binding cassette sub-family A member 3) (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (Xenobiotic-transporting ATPase ABCA3) (EC 7.6.2.2) [Cleaved into: 150 Kda mature form] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6238 | 0.049938562206 | 0.25 | NUS1 | DHDDS-NUS1 complex |
| REAC:R-HSA-5688399 | 0.0499436884912 | 0.25 | ABCA3 | Defective ABCA3 causes SMDP3 |
| REAC:R-HSA-5683678 | 0.0499436884912 | 0.25 | ABCA3 | Defective ABCA3 causes SMDP3 |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SPINT2 | NUS1 | 0.981 | 0.068 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM gupta_WMM | |
| SLC35F5 | SPINT2 | 0.975 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| SPINT2 | ABCA3 | 0.952 | 0.136 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ABCA3 | NUS1 | 0.877 | 0.058 | bioplex_WMM bioplex3_WMM WMM_only | |
| SLC35F5 | ABCA3 | 0.813 | bioplex_WMM bioplex3_WMM WMM_only | ||
| SLC35F5 | NUS1 | 0.326 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes