hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_05590.1

Confidence: Very High

Genename	Protein Name	Uniprot Annotation Score	Links
HEG1	Protein HEG homolog 1	5	UniProt NCBI
LGALS1	Galectin-1 (Gal-1) (14 kDa laminin-binding protein) (HLBP14) (14 kDa lectin) (Beta-galactoside-binding lectin L-14-I) (Galaptin) (HBL) (HPL) (Lactose-binding lectin 1) (Lectin galactoside-binding soluble 1) (Putative MAPK-activating protein PM12) (S-Lac lectin 1)	5	UniProt NCBI
NECTIN1	Nectin-1 (Herpes virus entry mediator C) (Herpesvirus entry mediator C) (HveC) (Herpesvirus Ig-like receptor) (HIgR) (Nectin cell adhesion molecule 1) (Poliovirus receptor-related protein 1) (CD antigen CD111)	5	UniProt NCBI
PTPRJ	Receptor-type tyrosine-protein phosphatase eta (Protein-tyrosine phosphatase eta) (R-PTP-eta) (EC 3.1.3.48) (Density-enhanced phosphatase 1) (DEP-1) (HPTP eta) (Protein-tyrosine phosphatase receptor type J) (R-PTP-J) (CD antigen CD148)	5	UniProt NCBI
ITGA1	Integrin alpha-1 (CD49 antigen-like family member A) (Laminin and collagen receptor) (VLA-1) (CD antigen CD49a)	5	UniProt NCBI
CSPG4	Chondroitin sulfate proteoglycan 4 (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan)	5	UniProt NCBI
ALCAM	CD166 antigen (Activated leukocyte cell adhesion molecule) (CD antigen CD166)	5	UniProt NCBI
CSF3	Granulocyte colony-stimulating factor (G-CSF) (Pluripoietin) (Filgrastim) (Lenograstim)	5	UniProt NCBI
MRC2	C-type mannose receptor 2 (C-type lectin domain family 13 member E) (Endocytic receptor 180) (Macrophage mannose receptor 2) (Urokinase-type plasminogen activator receptor-associated protein) (UPAR-associated protein) (Urokinase receptor-associated protein) (CD antigen CD280)	5	UniProt NCBI
LGALS3	Galectin-3 (Gal-3) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Galactose-specific lectin 3) (Galactoside-binding protein) (GALBP) (IgE-binding protein) (L-31) (Laminin-binding protein) (Lectin L-29) (Mac-2 antigen)	5	UniProt NCBI
LNPEP	Leucyl-cystinyl aminopeptidase (Cystinyl aminopeptidase) (EC 3.4.11.3) (Insulin-regulated membrane aminopeptidase) (Insulin-responsive aminopeptidase) (IRAP) (Oxytocinase) (OTase) (Placental leucine aminopeptidase) (P-LAP) [Cleaved into: Leucyl-cystinyl aminopeptidase, pregnancy serum form]	5	UniProt NCBI
ENPP4	Bis(5'-adenosyl)-triphosphatase ENPP4 (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Ectonucleotide pyrophosphatase/phosphodiesterase family member 4) (E-NPP 4) (NPP-4)	5	UniProt NCBI
PTGFRN	Prostaglandin F2 receptor negative regulator (CD9 partner 1) (CD9P-1) (Glu-Trp-Ile EWI motif-containing protein F) (EWI-F) (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD antigen CD315)	5	UniProt NCBI
KIAA0319L	Dyslexia-associated protein KIAA0319-like protein (Adeno-associated virus receptor) (AAVR)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:6951	0.000266552996475	0.142857142857	CSPG4 LGALS3	NG2-galectin-3-alpha3beta1-integrin complex
CORUM:1746	0.000931404176939	0.142857142857	LGALS1 LGALS3	SMN containing complex
KEGG:04520	0.00380039958933	0.214285714286	NECTIN1 HEG1 PTPRJ	Adherens junction
GO:0070161	0.0296086012863	0.5	ALCAM PTPRJ HEG1 NECTIN1 ITGA1 MRC2 CSPG4	anchoring junction
WP:WP5285	0.0318561232025	0.142857142857	LGALS1 LGALS3	Immune infiltration in pancreatic cancer
WP:WP5078	0.0484579411248	0.142857142857	LGALS1 LGALS3	T cell modulation in pancreatic cancer

Edges

Protein 1	Protein 2	Score	ProteomeHD
LGALS3	PTPRJ	0.998	0.226
LGALS1	ALCAM	0.998	0.106
LGALS1	PTGFRN	0.997	0.06
LGALS3	LNPEP	0.996	0.128
PTPRJ	ALCAM	0.989	0.152
LGALS3	ALCAM	0.989	0.112
PTPRJ	CSPG4	0.987	0.0581538461538
PTPRJ	CSF3	0.985
LGALS3	HEG1	0.982	0.052
ALCAM	CSPG4	0.981	0.086
LGALS1	ITGA1	0.981	0.18
KIAA0319L	LNPEP	0.98	0.058
LGALS3	CSPG4	0.979	0.056
LGALS3	MRC2	0.977	0.096
ENPP4	MRC2	0.976	0.108
ENPP4	PTPRJ	0.975	0.092
PTPRJ	LNPEP	0.971	0.118
ALCAM	MRC2	0.97	0.096
ITGA1	PTPRJ	0.969	0.046
HEG1	PTPRJ	0.969	0.07
HEG1	CSPG4	0.967	0.068
HEG1	ITGA1	0.967	0.074
HEG1	ALCAM	0.967	0.04
LGALS3	PTGFRN	0.966	0.0922222222222
PTPRJ	PTGFRN	0.963	0.088
MRC2	PTGFRN	0.962	0.07
KIAA0319L	CSPG4	0.961	0.066
KIAA0319L	PTPRJ	0.961	0.044
LGALS1	LGALS3	0.96	0.322
LGALS3	KIAA0319L	0.96	0.036
PTPRJ	MRC2	0.96	0.038
LGALS1	PTPRJ	0.959	0.162
ALCAM	PTGFRN	0.956	0.078
NECTIN1	ITGA1	0.955	0.056
HEG1	NECTIN1	0.954	0.052
HEG1	MRC2	0.954	0.124
LGALS1	NECTIN1	0.953	0.126
KIAA0319L	ALCAM	0.952	0.068
ITGA1	PTGFRN	0.952	0.118
ITGA1	LNPEP	0.951	0.04
PTGFRN	CSPG4	0.949	0.016
NECTIN1	PTPRJ	0.949	0.082
ITGA1	ALCAM	0.948	0.084
ITGA1	MRC2	0.946	0.074
PTGFRN	LNPEP	0.945	0.12
ITGA1	KIAA0319L	0.944	0.05
ENPP4	ALCAM	0.94	0.074
ALCAM	LNPEP	0.933	0.082
HEG1	KIAA0319L	0.933	0.066
HEG1	LNPEP	0.929	0.08
MRC2	CSPG4	0.919	0.074
NECTIN1	PTGFRN	0.901	0.016
MRC2	LNPEP	0.897	0.06
ENPP4	LGALS3	0.886	0.168
LGALS1	HEG1	0.878	0.116
NECTIN1	ALCAM	0.871	0.06
LGALS1	KIAA0319L	0.863	0.056
ITGA1	CSPG4	0.859	0.192
KIAA0319L	PTGFRN	0.854	0.038
ENPP4	PTGFRN	0.852	0.048
HEG1	PTGFRN	0.851	0.062
LNPEP	CSPG4	0.841	0.038
NECTIN1	KIAA0319L	0.838	0.036
NECTIN1	LNPEP	0.837	0.042
LGALS1	MRC2	0.835	0.128
LGALS1	LNPEP	0.828	0.094
ENPP4	ITGA1	0.791	0.078
ENPP4	KIAA0319L	0.767	0.09
ENPP4	CSPG4	0.766	0.088
NECTIN1	MRC2	0.742	0.0265
LGALS1	CSPG4	0.725	0.078
KIAA0319L	MRC2	0.688	0.062
ENPP4	LNPEP	0.614	0.064
LGALS3	ITGA1	0.596	0.174
NECTIN1	CSPG4	0.452	0.148
ENPP4	HEG1	0.42	0.072
ENPP4	NECTIN1	0.17	0.04
KIAA0319L	CSF3	0.114
LGALS3	NECTIN1	0.103	0.0663326923077
LGALS1	ENPP4	0.008	0.142

Related Complexes

Genename	Complexes
HEG1	huMAP3_01687.1 huMAP3_01717.1 huMAP3_02607.1 huMAP3_05584.1 huMAP3_05590.1 huMAP3_05876.1 huMAP3_06308.1 huMAP3_06892.1 huMAP3_08103.1 huMAP3_08689.1 huMAP3_09105.1 huMAP3_09336.1 huMAP3_10503.1 huMAP3_10744.1 huMAP3_10848.1 huMAP3_10980.1 huMAP3_11349.1 huMAP3_11697.1 huMAP3_14792.1 huMAP3_15183.1
LGALS1	huMAP3_00618.1 huMAP3_02873.1 huMAP3_03489.1 huMAP3_04614.1 huMAP3_05351.1 huMAP3_05590.1 huMAP3_06892.1 huMAP3_06908.1 huMAP3_06955.1 huMAP3_07927.1 huMAP3_09169.1 huMAP3_10859.1 huMAP3_10920.1 huMAP3_10980.1 huMAP3_11349.1 huMAP3_14792.1
NECTIN1	huMAP3_01687.1 huMAP3_01717.1 huMAP3_02607.1 huMAP3_03194.1 huMAP3_04614.1 huMAP3_05584.1 huMAP3_05590.1 huMAP3_06236.1 huMAP3_06308.1 huMAP3_06892.1 huMAP3_08103.1 huMAP3_08689.1 huMAP3_09105.1 huMAP3_09336.1 huMAP3_10503.1 huMAP3_10848.1 huMAP3_10920.1 huMAP3_10980.1 huMAP3_11349.1 huMAP3_11697.1 huMAP3_14792.1 huMAP3_15075.1
PTPRJ	huMAP3_02703.1 huMAP3_02887.1 huMAP3_04041.1 huMAP3_04390.1 huMAP3_05555.1 huMAP3_05584.1 huMAP3_05590.1 huMAP3_05876.1 huMAP3_06048.1 huMAP3_06955.1 huMAP3_08103.1 huMAP3_08689.1 huMAP3_09105.1 huMAP3_09336.1 huMAP3_10503.1 huMAP3_10744.1 huMAP3_10848.1 huMAP3_10980.1 huMAP3_11349.1 huMAP3_12283.1
ITGA1	huMAP3_01687.1 huMAP3_01717.1 huMAP3_02607.1 huMAP3_03194.1 huMAP3_04614.1 huMAP3_05584.1 huMAP3_05590.1 huMAP3_05876.1 huMAP3_06308.1 huMAP3_06892.1 huMAP3_06955.1 huMAP3_08103.1 huMAP3_08689.1 huMAP3_09105.1 huMAP3_09336.1 huMAP3_10503.1 huMAP3_10848.1 huMAP3_10920.1 huMAP3_10980.1 huMAP3_11349.1 huMAP3_11697.1 huMAP3_14792.1 huMAP3_15075.1
CSPG4	huMAP3_05584.1 huMAP3_05590.1 huMAP3_06048.1 huMAP3_06892.1 huMAP3_08103.1 huMAP3_08689.1 huMAP3_09105.1 huMAP3_09336.1 huMAP3_10503.1 huMAP3_10744.1 huMAP3_10848.1 huMAP3_10980.1 huMAP3_11349.1
ALCAM	huMAP3_02703.1 huMAP3_02887.1 huMAP3_05555.1 huMAP3_05584.1 huMAP3_05590.1 huMAP3_06308.1 huMAP3_08103.1 huMAP3_08689.1 huMAP3_09105.1 huMAP3_09336.1 huMAP3_10503.1 huMAP3_10744.1 huMAP3_10848.1 huMAP3_10980.1 huMAP3_11349.1
CSF3	huMAP3_02703.1 huMAP3_02887.1 huMAP3_04041.1 huMAP3_04390.1 huMAP3_05555.1 huMAP3_05590.1 huMAP3_06048.1 huMAP3_08103.1 huMAP3_08689.1 huMAP3_09105.1 huMAP3_09336.1 huMAP3_10503.1 huMAP3_10744.1 huMAP3_10848.1 huMAP3_10980.1 huMAP3_11179.1 huMAP3_12283.1 huMAP3_12398.1 huMAP3_13187.1 huMAP3_13701.1
MRC2	huMAP3_02703.1 huMAP3_02887.1 huMAP3_04041.1 huMAP3_04390.1 huMAP3_05584.1 huMAP3_05590.1 huMAP3_06048.1 huMAP3_06892.1 huMAP3_08103.1 huMAP3_08689.1 huMAP3_09105.1 huMAP3_09336.1 huMAP3_10503.1 huMAP3_10744.1 huMAP3_10848.1 huMAP3_10980.1 huMAP3_11349.1
LGALS3	huMAP3_01308.1 huMAP3_01622.1 huMAP3_05555.1 huMAP3_05584.1 huMAP3_05590.1 huMAP3_06308.1 huMAP3_08689.1 huMAP3_09336.1 huMAP3_10503.1 huMAP3_10848.1 huMAP3_10980.1 huMAP3_11349.1 huMAP3_14683.1
LNPEP	huMAP3_02887.1 huMAP3_04041.1 huMAP3_04390.1 huMAP3_05555.1 huMAP3_05584.1 huMAP3_05590.1 huMAP3_06048.1 huMAP3_08103.1 huMAP3_08689.1 huMAP3_09105.1 huMAP3_09336.1 huMAP3_10503.1 huMAP3_10848.1 huMAP3_10980.1 huMAP3_11349.1
ENPP4	huMAP3_01162.1 huMAP3_01717.1 huMAP3_02703.1 huMAP3_02887.1 huMAP3_04041.1 huMAP3_04384.1 huMAP3_05584.1 huMAP3_05590.1 huMAP3_06308.1 huMAP3_06892.1 huMAP3_08103.1 huMAP3_08689.1 huMAP3_09105.1 huMAP3_09336.1 huMAP3_10503.1 huMAP3_10744.1 huMAP3_10848.1 huMAP3_10980.1 huMAP3_11349.1
PTGFRN	huMAP3_02703.1 huMAP3_02887.1 huMAP3_04041.1 huMAP3_04390.1 huMAP3_04614.1 huMAP3_05555.1 huMAP3_05584.1 huMAP3_05590.1 huMAP3_06308.1 huMAP3_08103.1 huMAP3_08689.1 huMAP3_09105.1 huMAP3_09336.1 huMAP3_10503.1 huMAP3_10744.1 huMAP3_10848.1 huMAP3_10980.1 huMAP3_11349.1
KIAA0319L	huMAP3_01717.1 huMAP3_02887.1 huMAP3_03801.1 huMAP3_05584.1 huMAP3_05590.1 huMAP3_06308.1 huMAP3_06892.1 huMAP3_08103.1 huMAP3_08689.1 huMAP3_09105.1 huMAP3_09336.1 huMAP3_09837.1 huMAP3_10503.1 huMAP3_10848.1 huMAP3_10980.1 huMAP3_11349.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_05590.1