hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_05596.1
Confidence: Very High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
UBR5 | E3 ubiquitin-protein ligase UBR5 (EC 2.3.2.26) (E3 ubiquitin-protein ligase, HECT domain-containing 1) (HECT-type E3 ubiquitin transferase UBR5) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein) | 5 | UniProt   NCBI |
HUWE1 | E3 ubiquitin-protein ligase HUWE1 (EC 2.3.2.26) (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (HECT-type E3 ubiquitin transferase HUWE1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1) | 5 | UniProt   NCBI |
TANGO6 | Transport and Golgi organization protein 6 homolog (Transmembrane and coiled-coil domain-containing protein 7) | 3 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  KEGG:04120 | 0.00686279305854 | 0.666666666667 | UBR5 HUWE1 | Ubiquitin mediated proteolysis |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 TANGO6 |  UBR5 | 0.954 | 0.136           | bioplex_WMM     bioplex3_WMM     WMM_only     |
 UBR5 |  HUWE1 | 0.951 |            | bioplex_WMM     bioplex3_WMM     boldt     youn_WMM     fraction     boldt_WMM     treiber_WMM     |
 TANGO6 |  HUWE1 | 0.403 |            | bioplex_WMM     bioplex3_WMM     youn_WMM     WMM_only     |
Related Complexes
Genename | Complexes |
---|---|
UBR5 | huMAP3_03911.1 huMAP3_05596.1 huMAP3_10577.1 |
HUWE1 | huMAP3_03911.1 huMAP3_05596.1 huMAP3_10577.1 huMAP3_13407.1 |
TANGO6 | huMAP3_01311.1 huMAP3_01335.1 huMAP3_05029.1 huMAP3_05596.1 huMAP3_05710.1 huMAP3_10363.1 huMAP3_10441.1 |