hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05598.1
Complex Portal: CPX-10713
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KDM5C | Lysine-specific demethylase 5C (EC 1.14.11.67) (Histone demethylase JARID1C) (Jumonji/ARID domain-containing protein 1C) (Protein SmcX) (Protein Xe169) ([histone H3]-trimethyl-L-lysine(4) demethylase 5C) | 5 | UniProt NCBI |
| ZNF785 | Zinc finger protein 785 | 5 | UniProt NCBI |
| SUFU | Suppressor of fused homolog (SUFUH) | 5 | UniProt NCBI |
| NEBL | Nebulette (Actin-binding Z-disk protein) | 5 | UniProt NCBI |
| ZNF764 | Zinc finger protein 764 | 5 | UniProt NCBI |
| CYP24A1 | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (24-OHase) (Vitamin D(3) 24-hydroxylase) (EC 1.14.15.16) (Cytochrome P450 24A1) (Cytochrome P450-CC24) | 5 | UniProt NCBI |
| SMARCAD1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.4.12) (ATP-dependent helicase 1) (hHEL1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6668 | 0.0499958217778 | 0.142857142857 | SUFU | GLIS3-SUFU complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ZNF764 | SUFU | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| ZNF764 | NEBL | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| ZNF764 | KDM5C | 0.995 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| KDM5C | NEBL | 0.992 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| SMARCAD1 | ZNF785 | 0.988 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZNF764 | SMARCAD1 | 0.974 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| CYP24A1 | ZNF785 | 0.97 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| CYP24A1 | ZNF764 | 0.963 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| ZNF785 | SUFU | 0.961 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| SUFU | KDM5C | 0.884 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| SUFU | NEBL | 0.516 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | ||
| SMARCAD1 | KDM5C | 0.243 | bioplex3_WMM WMM_only | ||
| SMARCAD1 | NEBL | 0.209 | 0.038 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| CYP24A1 | NEBL | 0.195 | bioplex_WMM bioplex3_WMM WMM_only | ||
| CYP24A1 | SMARCAD1 | 0.096 | bioplex_WMM bioplex3_WMM WMM_only | ||
| CYP24A1 | SUFU | 0.073 | bioplex_WMM bioplex3_WMM WMM_only | ||
| SMARCAD1 | SUFU | 0.05 | 0.1 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
Related Complexes