hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05606.1
Complex Portal: CPX-22544
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MRPS17 | Small ribosomal subunit protein uS17m (28S ribosomal protein S17, mitochondrial) (MRP-S17) (S17mt) | 4 | UniProt NCBI |
| ERAL1 | GTPase Era, mitochondrial (H-ERA) (hERA) (Conserved ERA-like GTPase) (CEGA) (ERA-W) (ERA-like protein 1) | 5 | UniProt NCBI |
| MRPS27 | Small ribosomal subunit protein mS27 (28S ribosomal protein S27, mitochondrial) (MRP-S27) (S27mt) (Mitochondrial ribosomal protein S27) | 5 | UniProt NCBI |
| ZC3H3 | Zinc finger CCCH domain-containing protein 3 (Smad-interacting CPSF-like factor) | 5 | UniProt NCBI |
| HARS2 | Histidine--tRNA ligase, mitochondrial (EC 6.1.1.21) (Histidine--tRNA ligase-like) (Histidyl-tRNA synthetase) (HisRS) | 5 | UniProt NCBI |
| MRPS2 | Small ribosomal subunit protein uS2m (28S ribosomal protein S2, mitochondrial) (MRP-S2) (S2mt) | 5 | UniProt NCBI |
| MCAT | Malonyl-CoA-acyl carrier protein transacylase, mitochondrial (MCT) (EC 2.3.1.39) (Mitochondrial malonyl CoA:ACP acyltransferase) (Mitochondrial malonyltransferase) ([Acyl-carrier-protein] malonyltransferase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5389840 | 7.83760919267e-06 | 0.571428571429 | MRPS2 MRPS27 MRPS17 ERAL1 | Mitochondrial translation elongation |
| REAC:R-HSA-5368286 | 7.83760919267e-06 | 0.571428571429 | MRPS2 MRPS27 MRPS17 ERAL1 | Mitochondrial translation initiation |
| REAC:R-HSA-5419276 | 7.83760919267e-06 | 0.571428571429 | MRPS2 MRPS27 MRPS17 ERAL1 | Mitochondrial translation termination |
| REAC:R-HSA-5368287 | 1.02705207546e-05 | 0.571428571429 | MRPS2 MRPS27 MRPS17 ERAL1 | Mitochondrial translation |
| REAC:R-HSA-72766 | 1.13121236417e-05 | 0.714285714286 | MRPS2 HARS2 MRPS27 MRPS17 ERAL1 | Translation |
| CORUM:315 | 2.83572110865e-05 | 0.428571428571 | MRPS2 MRPS17 MRPS27 | 28S ribosomal subunit, mitochondrial |
| GO:0005759 | 0.000144902774387 | 0.857142857143 | MRPS27 HARS2 MCAT MRPS17 MRPS2 ERAL1 | mitochondrial matrix |
| CORUM:320 | 0.000526133422483 | 0.428571428571 | MRPS2 MRPS17 MRPS27 | 55S ribosome, mitochondrial |
| GO:0000314 | 0.016587316136 | 0.428571428571 | MRPS2 MRPS17 MRPS27 | organellar small ribosomal subunit |
| GO:0005763 | 0.016587316136 | 0.428571428571 | MRPS2 MRPS17 MRPS27 | mitochondrial small ribosomal subunit |
| HP:0010464 | 0.0383203414044 | 0.285714285714 | HARS2 ERAL1 | Streak ovary |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MRPS27 | MRPS17 | 0.998 | 0.962 |
structurally_consistent (Q8IVS2)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 boldt_WMM treiber_WMM |
| MRPS27 | MRPS2 | 0.998 | 0.998 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 boldt_WMM treiber_WMM |
| MRPS17 | MRPS2 | 0.996 | 0.988 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 boldt_WMM treiber_WMM | |
| MRPS17 | ERAL1 | 0.994 | 0.572 |
structurally_consistent (Q8IVS2)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| MRPS17 | MCAT | 0.991 | 0.314 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| MRPS27 | MCAT | 0.991 | 0.358 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| MRPS2 | MCAT | 0.986 | 0.272 |
structurally_consistent (dimer)
|
bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction |
| MRPS27 | ZC3H3 | 0.984 | 0.226 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ERAL1 | MRPS2 | 0.983 | 0.722 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 treiber_WMM |
| MRPS17 | ZC3H3 | 0.98 | 0.207666666667 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| HARS2 | MRPS17 | 0.975 | 0.14 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| ERAL1 | MCAT | 0.975 | 0.1 |
structurally_consistent (P82930)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| MRPS2 | ZC3H3 | 0.964 | 0.263 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| MRPS27 | ERAL1 | 0.962 | 0.46 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 treiber_WMM | |
| ERAL1 | ZC3H3 | 0.825 | 0.134 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| HARS2 | MRPS2 | 0.182 | 0.274 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| HARS2 | MCAT | 0.124 | 0.082 | bioplex_WMM bioplex3_WMM WMM_only | |
| HARS2 | ERAL1 | 0.106 | 0.066 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only treiber_WMM | |
| ZC3H3 | MCAT | 0.035 | 0.208 | bioplex3_HCT116 WMM_only | |
| HARS2 | ZC3H3 | 0.014 | 0.092 | bioplex_WMM bioplex3_WMM WMM_only | |
| MRPS27 | HARS2 | 0.014 | 0.122 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only treiber_WMM |
Related Complexes