hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05609.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KLHL1 | Kelch-like protein 1 | 4 | UniProt NCBI |
| PAMR1 | Inactive serine protease PAMR1 (Peptidase domain-containing protein associated with muscle regeneration 1) (Regeneration-associated muscle protease homolog) | 4 | UniProt NCBI |
| SNX5 | Sorting nexin-5 | 5 | UniProt NCBI |
| SNX6 | Sorting nexin-6 (TRAF4-associated factor 2) [Cleaved into: Sorting nexin-6, N-terminally processed] | 5 | UniProt NCBI |
| SNX1 | Sorting nexin-1 | 5 | UniProt NCBI |
| SNX2 | Sorting nexin-2 (Transformation-related gene 9 protein) (TRG-9) | 5 | UniProt NCBI |
| SNX32 | Sorting nexin-32 (Sorting nexin-6B) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0030905 | 9.2094208532e-10 | 0.571428571429 | SNX2 SNX5 SNX1 SNX6 | retromer, tubulation complex |
| KEGG:04144 | 1.00924159242e-06 | 0.714285714286 | SNX32 SNX2 SNX5 SNX1 SNX6 | Endocytosis |
| GO:0030904 | 3.56078348733e-06 | 0.571428571429 | SNX2 SNX5 SNX1 SNX6 | retromer complex |
| GO:0042147 | 5.78516855405e-06 | 0.714285714286 | SNX32 SNX2 SNX5 SNX1 SNX6 | retrograde transport, endosome to Golgi |
| CORUM:1058 | 2.05265451394e-05 | 0.285714285714 | SNX6 SNX1 | SNX complex (SNX1, SNX6) |
| GO:0016482 | 3.40876499387e-05 | 0.714285714286 | SNX32 SNX2 SNX5 SNX1 SNX6 | cytosolic transport |
| CORUM:1070 | 6.1565588648e-05 | 0.285714285714 | SNX1 SNX2 | SNX complex (SNX1, SNX1a, SNX2, SNX4) |
| CORUM:1096 | 6.1565588648e-05 | 0.285714285714 | SNX1 SNX2 | SNX complex (SNX1, SNX1a, SNX2, SNX4, PDGFRA) |
| CORUM:1091 | 0.000123103089524 | 0.285714285714 | SNX1 SNX2 | SNX complex (SNX1, SNX1a, SNX2, SNX4, LEPR) |
| CORUM:1093 | 0.000123103089524 | 0.285714285714 | SNX1 SNX2 | SNX complex (SNX1, SNX1a, SNX2, SNX4, INSR) |
| CORUM:1095 | 0.000123103089524 | 0.285714285714 | SNX1 SNX2 | SNX complex (SNX1, SNX1a, SNX2, SNX4, EGFR) |
| CORUM:657 | 0.000205125012531 | 0.285714285714 | SNX1 SNX2 | Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26A) |
| CORUM:1059 | 0.000205125012531 | 0.285714285714 | SNX1 SNX2 | Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26A) |
| CORUM:1060 | 0.000205125012531 | 0.285714285714 | SNX1 SNX2 | Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26B) |
| GO:0016197 | 0.00127236559123 | 0.714285714286 | SNX32 SNX2 SNX5 SNX1 SNX6 | endosomal transport |
| CORUM:1072 | 0.0499958217778 | 0.142857142857 | SNX2 | SNX complex (SNX2), oligomeric |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SNX5 | SNX1 | 1.0 | 0.326 | bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction |
| SNX6 | SNX1 | 1.0 | 0.562 | bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction |
| SNX1 | SNX2 | 1.0 | 0.378 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
| SNX1 | SNX32 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| SNX6 | SNX2 | 0.997 | 0.384 | bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM youn_WMM gupta_WMM fraction |
| SNX6 | SNX32 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| KLHL1 | SNX2 | 0.994 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PAMR1 | SNX1 | 0.992 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SNX2 | SNX32 | 0.987 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| SNX5 | SNX2 | 0.984 | 0.33 | bioplex_WMM Guru bioplex3_WMM youn_WMM gupta_WMM fraction |
| KLHL1 | SNX1 | 0.953 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PAMR1 | SNX32 | 0.902 | bioplex3_WMM WMM_only | |
| KLHL1 | SNX6 | 0.869 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| SNX5 | SNX6 | 0.865 | 0.146 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| PAMR1 | SNX5 | 0.86 | bioplex3_WMM WMM_only | |
| SNX5 | SNX32 | 0.73 | bioplex_WMM bioplex3_WMM WMM_only | |
| PAMR1 | SNX6 | 0.715 | bioplex3_WMM WMM_only | |
| PAMR1 | SNX2 | 0.356 | bioplex3_WMM WMM_only |
Related Complexes