hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05613.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SPECC1L | Cytospin-A (Renal carcinoma antigen NY-REN-22) (Sperm antigen with calponin homology and coiled-coil domains 1-like) (SPECC1-like protein) | 5 | UniProt NCBI |
| KIAA1958 | Uncharacterized protein KIAA1958 | 4 | UniProt NCBI |
| SPECC1 | Cytospin-B (Nuclear structure protein 5) (NSP5) (Sperm antigen HCMOGT-1) (Sperm antigen with calponin homology and coiled-coil domains 1) | 5 | UniProt NCBI |
| PLEKHG3 | Pleckstrin homology domain-containing family G member 3 (PH domain-containing family G member 3) | 5 | UniProt NCBI |
| ARHGEF17 | Rho guanine nucleotide exchange factor 17 (164 kDa Rho-specific guanine-nucleotide exchange factor) (p164-RhoGEF) (p164RhoGEF) (Tumor endothelial marker 4) | 4 | UniProt NCBI |
| MPRIP | Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip) | 5 | UniProt NCBI |
| DENND2B | DENN domain-containing protein 2B (HeLa tumor suppression 1) (Suppression of tumorigenicity 5 protein) | 5 | UniProt NCBI |
| TJP2 | Tight junction protein ZO-2 (Tight junction protein 2) (Zona occludens protein 2) (Zonula occludens protein 2) | 5 | UniProt NCBI |
| UACA | Uveal autoantigen with coiled-coil domains and ankyrin repeats | 5 | UniProt NCBI |
| ITPRID2 | Protein ITPRID2 (Cleavage signal-1 protein) (CS-1) (ITPR-interacting domain-containing protein 2) (Ki-ras-induced actin-interacting protein) (Sperm-specific antigen 2) | 5 | UniProt NCBI |
| RAI14 | Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Novel retinal pigment epithelial cell protein) (Retinoic acid-induced protein 14) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8980692 | 0.0254282217101 | 0.272727272727 | PLEKHG3 ARHGEF17 TJP2 | RHOA GTPase cycle |
| REAC:R-HSA-9012999 | 0.0382659460337 | 0.363636363636 | PLEKHG3 UACA ARHGEF17 TJP2 | RHO GTPase cycle |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD |
|---|---|---|---|
| SPECC1L | RAI14 | 0.995 | 0.18 |
| MPRIP | RAI14 | 0.995 | |
| MPRIP | SPECC1L | 0.994 | |
| ARHGEF17 | ITPRID2 | 0.993 | 0.08 |
| SPECC1L | SPECC1 | 0.99 | 0.114 |
| ARHGEF17 | MPRIP | 0.988 | |
| ARHGEF17 | SPECC1 | 0.987 | 0.06 |
| PLEKHG3 | RAI14 | 0.987 | 0.194 |
| SPECC1L | PLEKHG3 | 0.984 | 0.104 |
| SPECC1L | TJP2 | 0.984 | 0.128 |
| SPECC1 | PLEKHG3 | 0.982 | 0.134 |
| DENND2B | SPECC1 | 0.979 | 0.096 |
| SPECC1L | UACA | 0.979 | 0.084 |
| KIAA1958 | DENND2B | 0.978 | |
| ARHGEF17 | DENND2B | 0.978 | 0.174 |
| MPRIP | PLEKHG3 | 0.977 | |
| MPRIP | DENND2B | 0.976 | |
| ARHGEF17 | SPECC1L | 0.973 | 0.102 |
| ARHGEF17 | PLEKHG3 | 0.972 | 0.17 |
| DENND2B | RAI14 | 0.972 | 0.208518518519 |
| UACA | ITPRID2 | 0.97 | 0.11 |
| SPECC1L | ITPRID2 | 0.969 | 0.056 |
| DENND2B | ITPRID2 | 0.967 | 0.054 |
| TJP2 | PLEKHG3 | 0.967 | 0.136 |
| DENND2B | SPECC1L | 0.966 | 0.126 |
| MPRIP | ITPRID2 | 0.964 | |
| DENND2B | TJP2 | 0.963 | 0.056 |
| DENND2B | PLEKHG3 | 0.962 | 0.204 |
| ARHGEF17 | RAI14 | 0.962 | 0.168 |
| DENND2B | UACA | 0.962 | 0.066 |
| ITPRID2 | RAI14 | 0.955 | 0.072 |
| TJP2 | SPECC1 | 0.941 | 0.076 |
| PLEKHG3 | UACA | 0.941 | 0.162 |
| PLEKHG3 | ITPRID2 | 0.933 | 0.256 |
| TJP2 | ITPRID2 | 0.933 | 0.038 |
| ARHGEF17 | UACA | 0.932 | 0.104 |
| SPECC1 | ITPRID2 | 0.931 | 0.032 |
| SPECC1 | RAI14 | 0.913 | 0.116 |
| UACA | RAI14 | 0.913 | 0.154 |
| TJP2 | RAI14 | 0.861 | 0.134 |
| ARHGEF17 | TJP2 | 0.855 | 0.088 |
| MPRIP | SPECC1 | 0.796 | |
| SPECC1 | UACA | 0.794 | 0.04 |
| MPRIP | KIAA1958 | 0.423 | |
| MPRIP | UACA | 0.293 | |
| KIAA1958 | PLEKHG3 | 0.254 | |
| ARHGEF17 | KIAA1958 | 0.232 | |
| KIAA1958 | ITPRID2 | 0.063 | |
| KIAA1958 | SPECC1L | 0.063 | |
| KIAA1958 | RAI14 | 0.063 | |
| KIAA1958 | SPECC1 | 0.049 | |
| TJP2 | UACA | 0.048 | 0.046 |
| MPRIP | TJP2 | 0.019 |
Related Complexes