hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05627.1
Complex Portal: CPX-11139
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MITD1 | MIT domain-containing protein 1 | 5 | UniProt NCBI |
| APBA1 | Amyloid-beta A4 precursor protein-binding family A member 1 (Adapter protein X11alpha) (Neuron-specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint-1) | 5 | UniProt NCBI |
| DLG4 | Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9609736 | 0.00478550282195 | 0.666666666667 | APBA1 DLG4 | Assembly and cell surface presentation of NMDA receptors |
| REAC:R-HSA-6794361 | 0.00704293704569 | 0.666666666667 | APBA1 DLG4 | Neurexins and neuroligins |
| REAC:R-HSA-6794362 | 0.0164154902665 | 0.666666666667 | APBA1 DLG4 | Protein-protein interactions at synapses |
| REAC:R-HSA-442755 | 0.0214696523361 | 0.666666666667 | APBA1 DLG4 | Activation of NMDA receptors and postsynaptic events |
| CORUM:1909 | 0.0249718442456 | 0.333333333333 | DLG4 | APC-DLG4 complex |
| CORUM:6321 | 0.0249718442456 | 0.333333333333 | DLG4 | DLG4-DLGAP1-SHANK3 complex |
| CORUM:7234 | 0.0499402709677 | 0.333333333333 | DLG4 | DLGAP1-DLG4-DYNLL2 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MITD1 | APBA1 | 0.989 | 0.092 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| APBA1 | DLG4 | 0.981 | 0.106 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MITD1 | DLG4 | 0.214 | 0.106 | bioplex3_WMM WMM_only |
Related Complexes