List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_05634.1

Confidence: Very High   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
NSUN5	28S rRNA (cytosine-C(5))-methyltransferase (EC 2.1.1.-) (NOL1-related protein) (NOL1R) (NOL1/NOP2/Sun domain family member 5) (Williams-Beuren syndrome chromosomal region 20A protein)	5	UniProt   NCBI
PYCR3	Pyrroline-5-carboxylate reductase 3 (P5C reductase 3) (P5CR 3) (EC 1.5.1.2) (Pyrroline-5-carboxylate reductase-like protein)	5	UniProt   NCBI
PYCR2	Pyrroline-5-carboxylate reductase 2 (P5C reductase 2) (P5CR 2) (EC 1.5.1.2)	5	UniProt   NCBI
PYCR1	Pyrroline-5-carboxylate reductase 1, mitochondrial (P5C reductase 1) (P5CR 1) (EC 1.5.1.2)	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-8964539	2.31434954766e-07	0.75	PYCR3 PYCR1 PYCR2	Glutamate and glutamine metabolism
GO:0004735	1.53784171933e-06	0.75	PYCR3 PYCR1 PYCR2	pyrroline-5-carboxylate reductase activity
GO:0055129	1.53784171933e-06	0.75	PYCR3 PYCR1 PYCR2	L-proline biosynthetic process
GO:0006561	3.84440695359e-06	0.75	PYCR3 PYCR1 PYCR2	proline biosynthetic process
KEGG:00330	4.22779284136e-06	0.75	PYCR3 PYCR1 PYCR2	Arginine and proline metabolism
KEGG:01230	1.63910874597e-05	0.75	PYCR3 PYCR1 PYCR2	Biosynthesis of amino acids
GO:0006560	3.22863876272e-05	0.75	PYCR3 PYCR1 PYCR2	proline metabolic process
GO:0016646	0.000139871762976	0.75	PYCR3 PYCR1 PYCR2	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
GO:0009084	0.000174830724535	0.75	PYCR3 PYCR1 PYCR2	glutamine family amino acid biosynthetic process
GO:0016645	0.000372255315939	0.75	PYCR3 PYCR1 PYCR2	oxidoreductase activity, acting on the CH-NH group of donors
WP:WP497	0.000535373329556	0.5	PYCR3 PYCR1	Urea cycle and metabolism of amino groups
WP:WP4290	0.00188599942343	0.5	PYCR2 PYCR1	Metabolic reprogramming in colon cancer
GO:0170038	0.0037914498893	0.75	PYCR3 PYCR1 PYCR2	proteinogenic amino acid biosynthetic process
GO:0170034	0.00409056451107	0.75	PYCR3 PYCR1 PYCR2	L-amino acid biosynthetic process
GO:0009064	0.00582352741409	0.75	PYCR3 PYCR1 PYCR2	glutamine family amino acid metabolic process
GO:0008652	0.00582352741409	0.75	PYCR3 PYCR1 PYCR2	amino acid biosynthetic process
GO:1901607	0.00751763182363	0.75	PYCR3 PYCR1 PYCR2	alpha-amino acid biosynthetic process
REAC:R-HSA-71291	0.007608748274	0.75	PYCR3 PYCR1 PYCR2	Metabolism of amino acids and derivatives
GO:0170039	0.0405772675542	0.75	PYCR3 PYCR1 PYCR2	proteinogenic amino acid metabolic process
GO:0170033	0.0496619752722	0.75	PYCR3 PYCR1 PYCR2	L-amino acid metabolic process



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?	Evidence ?
PYCR2	PYCR1	1.0	0.416	hein_WMM     bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     boldt     youn_WMM     Malo     bioplex3_HCT116     gupta_WMM     fraction     boldt_WMM     treiber_WMM
PYCR2	PYCR3	0.999	0.032	bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     youn_WMM     bioplex3_HCT116
PYCR1	PYCR3	0.992	0.094	bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     boldt     youn_WMM     bioplex3_HCT116     boldt_WMM
NSUN5	PYCR2	0.958	0.08	hein_WMM     bioplex_WMM     bioplex3_WMM     WMM_only     treiber_WMM
NSUN5	PYCR1	0.934	0.08	hein_WMM     bioplex_WMM     bioplex3_WMM     WMM_only     treiber_WMM
NSUN5	PYCR3	0.054	0.022	bioplex_WMM     bioplex3_WMM     WMM_only





Related Complexes

Genename	Complexes
NSUN5	huMAP3_02071.1 huMAP3_03442.1 huMAP3_05194.1 huMAP3_05634.1 huMAP3_08672.1 huMAP3_09792.1 huMAP3_10767.1 huMAP3_10963.1
PYCR3	huMAP3_05612.1 huMAP3_05634.1 huMAP3_09725.1 huMAP3_10767.1 huMAP3_10867.1 huMAP3_11956.1
PYCR2	huMAP3_02071.1 huMAP3_05612.1 huMAP3_05634.1 huMAP3_10767.1
PYCR1	huMAP3_02071.1 huMAP3_05612.1 huMAP3_05634.1 huMAP3_07719.1 huMAP3_08568.1 huMAP3_09247.1 huMAP3_10767.1