hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05640.1
Complex Portal: CPX-15345
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SFTPC | Pulmonary surfactant-associated protein C (SP-C) (Pulmonary surfactant-associated proteolipid SPL(Val)) (SP5) | 5 | UniProt NCBI |
| PLXND1 | Plexin-D1 | 5 | UniProt NCBI |
| ADGRA3 | Adhesion G protein-coupled receptor A3 (G-protein coupled receptor 125) | 5 | UniProt NCBI |
| PTGS1 | Prostaglandin G/H synthase 1 (EC 1.14.99.1) (Cyclooxygenase-1) (COX-1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1) (Prostaglandin-endoperoxide synthase 1) | 5 | UniProt NCBI |
| B3GNT4 | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4 (EC 2.4.1.149) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4) (BGnT-4) (Beta-1,3-Gn-T4) (Beta-1,3-N-acetylglucosaminyltransferase 4) (Beta3Gn-T4) | 5 | UniProt NCBI |
| DDR1 | Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5654 | 0.049938562206 | 0.25 | PLXND1 | SEMA4A-PlexinD1 complex |
| CORUM:5658 | 0.049938562206 | 0.25 | PLXND1 | Nrp1-PlexinD1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PTGS1 | SFTPC | 0.999 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ADGRA3 | SFTPC | 0.995 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| B3GNT4 | SFTPC | 0.995 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PLXND1 | SFTPC | 0.993 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| DDR1 | SFTPC | 0.957 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PLXND1 | ADGRA3 | 0.784 | 0.106 | bioplex3_WMM WMM_only | |
| PTGS1 | B3GNT4 | 0.722 | bioplex3_WMM WMM_only | ||
| PTGS1 | PLXND1 | 0.688 | 0.098 | bioplex3_WMM WMM_only | |
| PTGS1 | ADGRA3 | 0.688 | 0.074 | bioplex3_WMM WMM_only | |
| DDR1 | B3GNT4 | 0.587 | bioplex3_WMM WMM_only | ||
| B3GNT4 | PLXND1 | 0.401 | bioplex3_WMM WMM_only | ||
| B3GNT4 | ADGRA3 | 0.401 | bioplex3_WMM WMM_only | ||
| PTGS1 | DDR1 | 0.117 | 0.082 | bioplex3_WMM WMM_only | |
| DDR1 | PLXND1 | 0.029 | 0.092 | bioplex3_WMM WMM_only | |
| DDR1 | ADGRA3 | 0.028 | 0.112 | bioplex3_WMM WMM_only |
Related Complexes