hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05648.1
Complex Portal: CPX-23628
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SHLD2 | Shieldin complex subunit 2 (Protein FAM35A) (RINN1-REV7-interacting novel NHEJ regulator 2) (Shield complex subunit 2) | 5 | UniProt NCBI |
| ARHGAP19 | Rho GTPase-activating protein 19 (Rho-type GTPase-activating protein 19) | 5 | UniProt NCBI |
| DEFA5 | Defensin alpha 5 (Defensin-5) (HD5(20-94)) [Cleaved into: HD5(23-94); HD5(29-94); HD5(56-94); HD5(63-94)] | 5 | UniProt NCBI |
| GLCE | D-glucuronyl C5-epimerase (EC 5.1.3.17) (Heparan sulfate C5-epimerase) (Hsepi) (Heparin/heparan sulfate:glucuronic acid C5-epimerase) (Heparosan-N-sulfate-glucuronate 5-epimerase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7578 | 0.049938562206 | 0.25 | SHLD2 | Shieldin complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SHLD2 | DEFA5 | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| GLCE | DEFA5 | 0.984 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| DEFA5 | ARHGAP19 | 0.981 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| SHLD2 | ARHGAP19 | 0.502 | bioplex_WMM bioplex3_WMM WMM_only | ||
| GLCE | ARHGAP19 | 0.255 | 0.148 | bioplex_WMM bioplex3_WMM WMM_only | |
| GLCE | SHLD2 | 0.172 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes