hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_05666.1
Complex Portal: CPX-22658
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SREBF2 | Sterol regulatory element-binding protein 2 (SREBP-2) (Class D basic helix-loop-helix protein 2) (bHLHd2) (Sterol regulatory element-binding transcription factor 2) [Cleaved into: Processed sterol regulatory element-binding protein 2 (Transcription factor SREBF2)] | 5 | UniProt NCBI |
| LGR4 | Leucine-rich repeat-containing G-protein coupled receptor 4 (G-protein coupled receptor 48) | 5 | UniProt NCBI |
| RDH10 | Retinol dehydrogenase 10 (EC 1.1.1.300) (Short chain dehydrogenase/reductase family 16C member 4) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7514 | 0.0499402709677 | 0.333333333333 | SREBF2 | SCAP-SREBF2 complex |
| CORUM:7516 | 0.0499402709677 | 0.333333333333 | SREBF2 | PAQR3-SREBF2 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| LGR4 | RDH10 | 0.974 | 0.096 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| LGR4 | SREBF2 | 0.959 | 0.072 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SREBF2 | RDH10 | 0.434 | 0.102 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes