hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05667.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TMEM31 | Transmembrane protein 31 | 2 | UniProt NCBI |
| VPS13D | Intermembrane lipid transfer protein VPS13D (Vacuolar protein sorting-associated protein 13D) | 5 | UniProt NCBI |
| UBQLN1 | Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1) | 5 | UniProt NCBI |
| UBQLN2 | Ubiquilin-2 (Chap1) (DSK2 homolog) (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC-2) (Ubiquitin-like product Chap1/Dsk2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5209 | 5.12488211613e-05 | 0.5 | UBQLN1 UBQLN2 | Ubiquilin-proteasome complex |
| KEGG:04141 | 0.0298999303213 | 0.5 | UBQLN1 UBQLN2 | Protein processing in endoplasmic reticulum |
| REAC:R-HSA-8856825 | 0.0444386798825 | 0.5 | UBQLN1 UBQLN2 | Cargo recognition for clathrin-mediated endocytosis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TMEM31 | UBQLN2 | 0.983 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TMEM31 | UBQLN1 | 0.98 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TMEM31 | VPS13D | 0.96 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| UBQLN1 | UBQLN2 | 0.698 | bioplex_WMM bioplex3_WMM fraction | |
| VPS13D | UBQLN2 | 0.034 | 0.03 | bioplex3_WMM WMM_only |
| VPS13D | UBQLN1 | 0.019 | bioplex3_WMM WMM_only |
Related Complexes