hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05694.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| BIRC3 | Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin transferase BIRC3) (TNFR2-TRAF-signaling complex protein 1) | 5 | UniProt NCBI |
| BCL10 | B-cell lymphoma/leukemia 10 (B-cell CLL/lymphoma 10) (Bcl-10) (CARD-containing molecule enhancing NF-kappa-B) (CARD-like apoptotic protein) (hCLAP) (CED-3/ICH-1 prodomain homologous E10-like regulator) (CIPER) (Cellular homolog of vCARMEN) (cCARMEN) (Cellular-E10) (c-E10) (Mammalian CARD-containing adapter molecule E10) (mE10) | 5 | UniProt NCBI |
| MIS18BP1 | Mis18-binding protein 1 (Kinetochore-associated protein KNL-2 homolog) (HsKNL-2) (P243) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0012123 | 7.59175135241e-05 | 0.666666666667 | BIRC3 BCL10 | Posterior uveitis |
| HP:0012191 | 0.00151751896202 | 0.666666666667 | BIRC3 BCL10 | B-cell lymphoma |
| KEGG:04064 | 0.0024036675985 | 0.666666666667 | BIRC3 BCL10 | NF-kappa B signaling pathway |
| HP:0100721 | 0.00348901893966 | 0.666666666667 | BIRC3 BCL10 | Mediastinal lymphadenopathy |
| HP:0012539 | 0.00708857159683 | 0.666666666667 | BIRC3 BCL10 | Non-Hodgkin lymphoma |
| HP:0000554 | 0.00936084070842 | 0.666666666667 | BIRC3 BCL10 | Uveitis |
| HP:0045026 | 0.00985306624309 | 0.666666666667 | BIRC3 BCL10 | Abnormal mediastinum morphology |
| HP:0045027 | 0.0136509708315 | 0.666666666667 | BIRC3 BCL10 | Abnormality of the thoracic cavity |
| HP:0002113 | 0.0142438401108 | 0.666666666667 | BIRC3 BCL10 | Pulmonary infiltrates |
| CORUM:2052 | 0.0249718442456 | 0.333333333333 | BCL10 | BCL10 homo-oligomer complex |
| HP:0000614 | 0.0254384546332 | 0.666666666667 | BIRC3 BCL10 | Abnormal nasolacrimal system morphology |
| CORUM:2053 | 0.0499402709677 | 0.333333333333 | BCL10 | BCL10-MALT1 complex |
| CORUM:2752 | 0.0499402709677 | 0.333333333333 | BCL10 | CARMA1-BCL10-MALT1 complex |
| CORUM:2753 | 0.0499402709677 | 0.333333333333 | BCL10 | FYB-CARMA1-BCL-10-MALT1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| BIRC3 | BCL10 | 0.996 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| BCL10 | MIS18BP1 | 0.951 | 0.044 | hein_WMM bioplex3_WMM WMM_only |
Related Complexes