hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05711.1
Complex Portal: CPX-15882
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NOB1 | RNA-binding protein NOB1 (EC 3.1.-.-) (Phosphorylation regulatory protein HP-10) (Protein ART-4) | 5 | UniProt NCBI |
| LSG1 | Large subunit GTPase 1 homolog (hLsg1) (EC 3.6.1.-) | 5 | UniProt NCBI |
| MTDH | Protein LYRIC (3D3/LYRIC) (Astrocyte elevated gene-1 protein) (AEG-1) (Lysine-rich CEACAM1 co-isolated protein) (Metadherin) (Metastasis adhesion protein) | 5 | UniProt NCBI |
| AVEN | Cell death regulator Aven | 4 | UniProt NCBI |
| CAPRIN1 | Caprin-1 (Cell cycle-associated protein 1) (Cytoplasmic activation- and proliferation-associated protein 1) (GPI-anchored membrane protein 1) (GPI-anchored protein p137) (GPI-p137) (p137GPI) (Membrane component chromosome 11 surface marker 1) (RNA granule protein 105) | 5 | UniProt NCBI |
| CCDC124 | Coiled-coil domain-containing protein 124 | 5 | UniProt NCBI |
| FOCAD | Focadhesin | 5 | UniProt NCBI |
| DDX5 | Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5) (RNA helicase p68) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0440342 | 0.00086429766098 | 1.0 | CAPRIN1 CCDC124 DDX5 LSG1 MTDH AVEN NOB1 FOCAD | skeletal muscle; myocytes[>=Medium] |
| HPA:0050012 | 0.0016752314762 | 0.75 | CAPRIN1 LSG1 DDX5 MTDH AVEN CCDC124 | breast; adipocytes[>=Medium] |
| HPA:0340462 | 0.0109830778194 | 0.75 | CAPRIN1 CCDC124 DDX5 MTDH AVEN NOB1 | ovary; ovarian stroma cells[>=Medium] |
| HPA:0500111 | 0.0136953470085 | 0.75 | CAPRIN1 CCDC124 FOCAD LSG1 NOB1 MTDH | soft tissue 1; chondrocytes[>=Low] |
| HPA:0570732 | 0.0147630653452 | 1.0 | CAPRIN1 CCDC124 DDX5 LSG1 MTDH AVEN NOB1 FOCAD | testis; Leydig cells[>=Medium] |
| HPA:0010012 | 0.016644306355 | 0.75 | CAPRIN1 LSG1 DDX5 MTDH AVEN CCDC124 | adipose tissue; adipocytes[>=Medium] |
| HPA:0170251 | 0.0169899383154 | 0.875 | CAPRIN1 CCDC124 DDX5 LSG1 MTDH AVEN NOB1 | endometrium 2; cells in endometrial stroma[>=Low] |
| HPA:0590052 | 0.0226051516919 | 1.0 | CAPRIN1 CCDC124 DDX5 LSG1 MTDH AVEN NOB1 FOCAD | thyroid gland; glandular cells[>=Medium] |
| HPA:0180052 | 0.024892450361 | 1.0 | CAPRIN1 CCDC124 DDX5 LSG1 MTDH AVEN NOB1 FOCAD | epididymis; glandular cells[>=Medium] |
| HPA:0630222 | 0.0249041935213 | 0.875 | CAPRIN1 CCDC124 DDX5 LSG1 MTDH AVEN NOB1 | cervix; squamous epithelial cells[>=Medium] |
| HPA:0290401 | 0.0249315740551 | 1.0 | CAPRIN1 CCDC124 DDX5 LSG1 MTDH AVEN NOB1 FOCAD | liver; hepatocytes[>=Low] |
| HPA:0500112 | 0.0262861553076 | 0.625 | FOCAD NOB1 MTDH CAPRIN1 LSG1 | soft tissue 1; chondrocytes[>=Medium] |
| HPA:0440341 | 0.0294872241715 | 1.0 | CAPRIN1 CCDC124 DDX5 LSG1 MTDH AVEN NOB1 FOCAD | skeletal muscle; myocytes[>=Low] |
| HPA:0440000 | 0.0294872241715 | 1.0 | CAPRIN1 CCDC124 DDX5 LSG1 MTDH AVEN NOB1 FOCAD | skeletal muscle |
| KEGG:03008 | 0.0334539586856 | 0.25 | NOB1 LSG1 | Ribosome biogenesis in eukaryotes |
| HPA:0610832 | 0.0370714569997 | 1.0 | CAPRIN1 CCDC124 DDX5 LSG1 MTDH AVEN NOB1 FOCAD | urinary bladder; urothelial cells[>=Medium] |
| HPA:0020052 | 0.0372379764948 | 1.0 | CAPRIN1 CCDC124 DDX5 LSG1 MTDH AVEN NOB1 FOCAD | adrenal gland; glandular cells[>=Medium] |
| HPA:0340461 | 0.0402241829976 | 0.875 | CAPRIN1 CCDC124 DDX5 LSG1 MTDH AVEN NOB1 | ovary; ovarian stroma cells[>=Low] |
| HPA:0090163 | 0.0403815411115 | 0.625 | DDX5 LSG1 CCDC124 CAPRIN1 AVEN | cerebellum; Purkinje cells[High] |
| HPA:0500113 | 0.0459092664982 | 0.375 | CAPRIN1 MTDH FOCAD | soft tissue 1; chondrocytes[High] |
| HPA:0080132 | 0.0465230549318 | 0.875 | CAPRIN1 CCDC124 DDX5 LSG1 MTDH AVEN NOB1 | caudate; neuronal cells[>=Medium] |
| HPA:0090162 | 0.0473766132884 | 0.875 | CAPRIN1 CCDC124 DDX5 LSG1 MTDH AVEN NOB1 | cerebellum; Purkinje cells[>=Medium] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| FOCAD | AVEN | 0.995 | 0.372 | hein_WMM bioplex3_WMM WMM_only boldt_WMM | |
| NOB1 | FOCAD | 0.995 | 0.052 | hein_WMM bioplex3_WMM youn_WMM WMM_only | |
| NOB1 | AVEN | 0.993 | 0.046 | hein_WMM bioplex3_WMM WMM_only | |
| FOCAD | MTDH | 0.986 | 0.042 | hein_WMM bioplex3_WMM youn_WMM WMM_only | |
| FOCAD | CCDC124 | 0.981 | 0.054 | hein_WMM bioplex3_WMM youn_WMM WMM_only | |
| AVEN | MTDH | 0.978 | 0.094 | hein_WMM bioplex3_WMM youn_WMM WMM_only | |
| FOCAD | DDX5 | 0.978 | 0.086 | hein_WMM bioplex3_WMM WMM_only treiber_WMM | |
| AVEN | CAPRIN1 | 0.97 | 0.118 | hein_WMM bioplex3_WMM youn_WMM WMM_only | |
| AVEN | CCDC124 | 0.97 | 0.098 | hein_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| AVEN | LSG1 | 0.964 | 0.048 | hein_WMM bioplex3_WMM youn_WMM WMM_only | |
| AVEN | DDX5 | 0.963 | 0.1648 | hein_WMM bioplex3_WMM gupta_WMM WMM_only | |
| FOCAD | LSG1 | 0.932 | 0.03 | hein_WMM bioplex3_WMM youn_WMM WMM_only | |
| MTDH | LSG1 | 0.932 | 0.134 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| FOCAD | CAPRIN1 | 0.904 | 0.062 | hein_WMM bioplex3_WMM youn_WMM fraction | |
| CCDC124 | DDX5 | 0.763 | 0.358 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM fraction | |
| CCDC124 | LSG1 | 0.678 | 0.132 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction | |
| NOB1 | CCDC124 | 0.604 | 0.17 | hein_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| NOB1 | CAPRIN1 | 0.577 | 0.22 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM | |
| CAPRIN1 | MTDH | 0.424 | 0.142 | youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM | |
| CCDC124 | CAPRIN1 | 0.412 | 0.366 | hein_WMM youn () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction | |
| NOB1 | LSG1 | 0.167 | 0.19 | hein_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| DDX5 | MTDH | 0.15 | 0.178 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM gupta_WMM treiber_WMM | |
| CCDC124 | MTDH | 0.14 | 0.104 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM | |
| NOB1 | MTDH | 0.139 | 0.058 | bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| CAPRIN1 | LSG1 | 0.059 | 0.126 | youn () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| NOB1 | DDX5 | 0.032 | 0.292 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM gupta_WMM fraction | |
| DDX5 | LSG1 | 0.031 | 0.244 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| DDX5 | CAPRIN1 | 0.009 | 0.594 | youn () bioplex_WMM bioplex3_WMM gupta_WMM treiber_WMM WMM_only |
Related Complexes