hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_05711.1

Confidence: Very High

Genename	Protein Name	Uniprot Annotation Score	Links
NOB1	RNA-binding protein NOB1 (EC 3.1.-.-) (Phosphorylation regulatory protein HP-10) (Protein ART-4)	5	UniProt NCBI
LSG1	Large subunit GTPase 1 homolog (hLsg1) (EC 3.6.1.-)	5	UniProt NCBI
MTDH	Protein LYRIC (3D3/LYRIC) (Astrocyte elevated gene-1 protein) (AEG-1) (Lysine-rich CEACAM1 co-isolated protein) (Metadherin) (Metastasis adhesion protein)	5	UniProt NCBI
AVEN	Cell death regulator Aven	4	UniProt NCBI
CAPRIN1	Caprin-1 (Cell cycle-associated protein 1) (Cytoplasmic activation- and proliferation-associated protein 1) (GPI-anchored membrane protein 1) (GPI-anchored protein p137) (GPI-p137) (p137GPI) (Membrane component chromosome 11 surface marker 1) (RNA granule protein 105)	5	UniProt NCBI
CCDC124	Coiled-coil domain-containing protein 124	5	UniProt NCBI
FOCAD	Focadhesin	5	UniProt NCBI
DDX5	Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5) (RNA helicase p68)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
HPA:0440342	0.00086429766098	1.0	DDX5 NOB1 FOCAD MTDH CCDC124 LSG1 AVEN CAPRIN1	skeletal muscle; myocytes[>=Medium]
HPA:0050012	0.0016752314762	0.75	MTDH AVEN CCDC124 LSG1 DDX5 CAPRIN1	breast; adipocytes[>=Medium]
HPA:0340462	0.0109830778194	0.75	NOB1 CAPRIN1 MTDH CCDC124 DDX5 AVEN	ovary; ovarian stroma cells[>=Medium]
HPA:0500111	0.0136953470085	0.75	NOB1 FOCAD CCDC124 LSG1 MTDH CAPRIN1	soft tissue 1; chondrocytes[>=Low]
HPA:0570732	0.0147630653452	1.0	DDX5 NOB1 FOCAD MTDH CCDC124 LSG1 AVEN CAPRIN1	testis; Leydig cells[>=Medium]
HPA:0010012	0.016644306355	0.75	MTDH AVEN CCDC124 LSG1 DDX5 CAPRIN1	adipose tissue; adipocytes[>=Medium]
HPA:0170251	0.0169899383154	0.875	DDX5 NOB1 MTDH CCDC124 LSG1 AVEN CAPRIN1	endometrium 2; cells in endometrial stroma[>=Low]
HPA:0590052	0.0226051516919	1.0	DDX5 NOB1 FOCAD MTDH CCDC124 LSG1 AVEN CAPRIN1	thyroid gland; glandular cells[>=Medium]
HPA:0180052	0.024892450361	1.0	DDX5 NOB1 FOCAD MTDH CCDC124 LSG1 AVEN CAPRIN1	epididymis; glandular cells[>=Medium]
HPA:0630222	0.0249041935213	0.875	DDX5 NOB1 MTDH CCDC124 LSG1 AVEN CAPRIN1	cervix; squamous epithelial cells[>=Medium]
HPA:0290401	0.0249315740551	1.0	DDX5 NOB1 FOCAD MTDH CCDC124 LSG1 AVEN CAPRIN1	liver; hepatocytes[>=Low]
HPA:0500112	0.0262861553076	0.625	NOB1 FOCAD LSG1 CAPRIN1 MTDH	soft tissue 1; chondrocytes[>=Medium]
HPA:0440341	0.0294872241715	1.0	DDX5 NOB1 FOCAD MTDH CCDC124 LSG1 AVEN CAPRIN1	skeletal muscle; myocytes[>=Low]
HPA:0440000	0.0294872241715	1.0	DDX5 NOB1 FOCAD MTDH CCDC124 LSG1 AVEN CAPRIN1	skeletal muscle
KEGG:03008	0.0334539586856	0.25	NOB1 LSG1	Ribosome biogenesis in eukaryotes
HPA:0610832	0.0370714569997	1.0	DDX5 NOB1 FOCAD MTDH CCDC124 LSG1 AVEN CAPRIN1	urinary bladder; urothelial cells[>=Medium]
HPA:0020052	0.0372379764948	1.0	DDX5 NOB1 FOCAD MTDH CCDC124 LSG1 AVEN CAPRIN1	adrenal gland; glandular cells[>=Medium]
HPA:0340461	0.0402241829976	0.875	DDX5 NOB1 MTDH CCDC124 LSG1 AVEN CAPRIN1	ovary; ovarian stroma cells[>=Low]
HPA:0090163	0.0403815411115	0.625	AVEN DDX5 CCDC124 LSG1 CAPRIN1	cerebellum; Purkinje cells[High]
HPA:0500113	0.0459092664982	0.375	MTDH FOCAD CAPRIN1	soft tissue 1; chondrocytes[High]
HPA:0080132	0.0465230549318	0.875	DDX5 NOB1 MTDH CCDC124 LSG1 AVEN CAPRIN1	caudate; neuronal cells[>=Medium]
HPA:0090162	0.0473766132884	0.875	DDX5 NOB1 MTDH CCDC124 LSG1 AVEN CAPRIN1	cerebellum; Purkinje cells[>=Medium]

Edges

Protein 1	Protein 2	Score	ProteomeHD	Evidence
FOCAD	AVEN	0.995	0.372	hein_WMM bioplex3_WMM WMM_only boldt_WMM
NOB1	FOCAD	0.995	0.052	hein_WMM bioplex3_WMM youn_WMM WMM_only
NOB1	AVEN	0.993	0.046	hein_WMM bioplex3_WMM WMM_only
FOCAD	MTDH	0.986	0.042	hein_WMM bioplex3_WMM youn_WMM WMM_only
FOCAD	CCDC124	0.981	0.054	hein_WMM bioplex3_WMM youn_WMM WMM_only
AVEN	MTDH	0.978	0.094	hein_WMM bioplex3_WMM youn_WMM WMM_only
FOCAD	DDX5	0.978	0.086	hein_WMM bioplex3_WMM WMM_only treiber_WMM
AVEN	CAPRIN1	0.97	0.118	hein_WMM bioplex3_WMM youn_WMM WMM_only
AVEN	CCDC124	0.97	0.098	hein_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only
AVEN	LSG1	0.964	0.048	hein_WMM bioplex3_WMM youn_WMM WMM_only
AVEN	DDX5	0.963	0.1648	hein_WMM bioplex3_WMM gupta_WMM WMM_only
FOCAD	LSG1	0.932	0.03	hein_WMM bioplex3_WMM youn_WMM WMM_only
MTDH	LSG1	0.932	0.134	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only
FOCAD	CAPRIN1	0.904	0.062	hein_WMM bioplex3_WMM youn_WMM fraction
CCDC124	DDX5	0.763	0.358	hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM fraction
CCDC124	LSG1	0.678	0.132	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction
NOB1	CCDC124	0.604	0.17	hein_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only
NOB1	CAPRIN1	0.577	0.22	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM
CAPRIN1	MTDH	0.424	0.142	youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM
CCDC124	CAPRIN1	0.412	0.366	hein_WMM youn () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction
NOB1	LSG1	0.167	0.19	hein_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only
DDX5	MTDH	0.15	0.178	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM gupta_WMM treiber_WMM
CCDC124	MTDH	0.14	0.104	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM
NOB1	MTDH	0.139	0.058	bioplex3_WMM youn_WMM gupta_WMM WMM_only
CAPRIN1	LSG1	0.059	0.126	youn () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only
NOB1	DDX5	0.032	0.292	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM gupta_WMM fraction
DDX5	LSG1	0.031	0.244	hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM WMM_only
DDX5	CAPRIN1	0.009	0.594	youn () bioplex_WMM bioplex3_WMM gupta_WMM treiber_WMM WMM_only

Related Complexes

Genename	Complexes
NOB1	huMAP3_00319.1 huMAP3_05398.1 huMAP3_05711.1 huMAP3_07574.1 huMAP3_07909.1 huMAP3_09754.1 huMAP3_09891.1 huMAP3_10631.1 huMAP3_11111.1
LSG1	huMAP3_03324.1 huMAP3_04327.1 huMAP3_05711.1 huMAP3_06830.1 huMAP3_06888.1 huMAP3_08526.1 huMAP3_09754.1 huMAP3_09891.1 huMAP3_10631.1 huMAP3_10976.1 huMAP3_11111.1 huMAP3_14270.1 huMAP3_14559.1
MTDH	huMAP3_02176.1 huMAP3_05398.1 huMAP3_05711.1 huMAP3_08526.1 huMAP3_09891.1 huMAP3_10631.1 huMAP3_11111.1 huMAP3_11159.1 huMAP3_14270.1 huMAP3_14559.1
AVEN	huMAP3_00371.1 huMAP3_01744.1 huMAP3_05711.1 huMAP3_06830.1 huMAP3_06888.1 huMAP3_07538.1 huMAP3_07909.1 huMAP3_08526.1 huMAP3_09754.1 huMAP3_09891.1 huMAP3_10631.1 huMAP3_10976.1 huMAP3_11111.1 huMAP3_14559.1
CAPRIN1	huMAP3_01928.1 huMAP3_02784.1 huMAP3_04258.1 huMAP3_04327.1 huMAP3_05303.1 huMAP3_05711.1 huMAP3_06888.1 huMAP3_07425.1 huMAP3_07909.1 huMAP3_07963.1 huMAP3_08326.1 huMAP3_08526.1 huMAP3_09383.1 huMAP3_09754.1 huMAP3_09891.1 huMAP3_10207.1 huMAP3_10307.1 huMAP3_10364.1 huMAP3_10631.1 huMAP3_10976.1 huMAP3_11111.1 huMAP3_14270.1 huMAP3_14559.1
CCDC124	huMAP3_00588.1 huMAP3_01744.1 huMAP3_02373.1 huMAP3_05711.1 huMAP3_06888.1 huMAP3_07523.1 huMAP3_07909.1 huMAP3_08025.1 huMAP3_08220.1 huMAP3_08526.1 huMAP3_09594.1 huMAP3_09754.1 huMAP3_09891.1 huMAP3_10359.1 huMAP3_10631.1 huMAP3_10719.1 huMAP3_11021.1 huMAP3_11099.1 huMAP3_11111.1 huMAP3_14270.1 huMAP3_14559.1
FOCAD	huMAP3_00319.1 huMAP3_05398.1 huMAP3_05711.1 huMAP3_06830.1 huMAP3_07574.1 huMAP3_07909.1 huMAP3_09754.1 huMAP3_09891.1 huMAP3_10631.1 huMAP3_11111.1
DDX5	huMAP3_01663.1 huMAP3_01744.1 huMAP3_05398.1 huMAP3_05711.1 huMAP3_07909.1 huMAP3_08401.1 huMAP3_09023.1 huMAP3_09754.1 huMAP3_10416.1 huMAP3_10631.1 huMAP3_11069.1 huMAP3_11111.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_05711.1