List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_05722.1

Confidence: Very High   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
SAP18	Histone deacetylase complex subunit SAP18 (18 kDa Sin3-associated polypeptide) (2HOR0202) (Cell growth-inhibiting gene 38 protein) (Sin3-associated polypeptide p18)	5	UniProt   NCBI
SETD2	Histone-lysine N-methyltransferase SETD2 (EC 2.1.1.359) (HIF-1) (Huntingtin yeast partner B) (Huntingtin-interacting protein 1) (HIP-1) (Huntingtin-interacting protein B) (Lysine N-methyltransferase 3A) (Protein-lysine N-methyltransferase SETD2) (EC 2.1.1.-) (SET domain-containing protein 2) (hSET2) (p231HBP)	5	UniProt   NCBI
ACIN1	Apoptotic chromatin condensation inducer in the nucleus (Acinus)	5	UniProt   NCBI
RNPS1	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2)	5	UniProt   NCBI
GPATCH8	G patch domain-containing protein 8	4	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:760	2.80233355908e-09	0.6	SAP18 RNPS1 ACIN1	Apoptosis- and splicing-associated protein complex (ASAP-L), SAP18, RNPS1, Acinus-L
GO:0061574	3.84440695359e-06	0.6	SAP18 RNPS1 ACIN1	ASAP complex
KEGG:03015	0.000112348611335	0.6	SAP18 RNPS1 ACIN1	mRNA surveillance pathway
KEGG:03013	0.000153958097406	0.6	SAP18 RNPS1 ACIN1	Nucleocytoplasmic transport
GO:0048025	0.000537554131189	0.6	SAP18 RNPS1 ACIN1	negative regulation of mRNA splicing, via spliceosome
GO:0050686	0.000783132248318	0.6	SAP18 RNPS1 ACIN1	negative regulation of mRNA processing
GO:0035145	0.00109385703544	0.6	SAP18 RNPS1 ACIN1	exon-exon junction complex
GO:0033119	0.00127603542925	0.6	SAP18 RNPS1 ACIN1	negative regulation of RNA splicing
REAC:R-HSA-72163	0.00407681863898	0.6	SAP18 RNPS1 ACIN1	mRNA Splicing - Major Pathway
REAC:R-HSA-72172	0.00451677062682	0.6	SAP18 RNPS1 ACIN1	mRNA Splicing
REAC:R-HSA-72203	0.0102904130445	0.6	SAP18 RNPS1 ACIN1	Processing of Capped Intron-Containing Pre-mRNA
HPA:0090933	0.0102944856463	0.4	SAP18 ACIN1	cerebellum; GLUC cells - nucleus[High]
HPA:0090913	0.0124256023723	0.4	SAP18 ACIN1	cerebellum; Bergmann glia - nucleus[High]
HPA:0090983	0.0205780624461	0.4	SAP18 ACIN1	cerebellum; granular cells - nucleus[High]
HPA:0090963	0.0217394744763	0.4	SAP18 ACIN1	cerebellum; Purkinje cells - nucleus[High]
HPA:0090912	0.0223320121016	0.4	SAP18 ACIN1	cerebellum; Bergmann glia - nucleus[>=Medium]
HPA:0090932	0.0235407341342	0.4	SAP18 ACIN1	cerebellum; GLUC cells - nucleus[>=Medium]
HPA:0090911	0.0260526733167	0.4	SAP18 ACIN1	cerebellum; Bergmann glia - nucleus[>=Low]
HPA:0090931	0.0280192074722	0.4	SAP18 ACIN1	cerebellum; GLUC cells - nucleus[>=Low]
HPA:0091082	0.0381295382519	0.4	SAP18 ACIN1	cerebellum; white matter cells - nucleus[>=Medium]
HPA:0091013	0.0389103706046	0.4	SAP18 ACIN1	cerebellum; molecular layer cells - nucleus[High]
HPA:0090962	0.0412996825225	0.4	SAP18 ACIN1	cerebellum; Purkinje cells - nucleus[>=Medium]
HPA:0091081	0.0429315368196	0.4	SAP18 ACIN1	cerebellum; white matter cells - nucleus[>=Low]
HPA:0090961	0.0471474108311	0.4	SAP18 ACIN1	cerebellum; Purkinje cells - nucleus[>=Low]
HPA:0090982	0.0471474108311	0.4	SAP18 ACIN1	cerebellum; granular cells - nucleus[>=Medium]



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?	Evidence ?
ACIN1	SAP18	1.0		hein_WMM     bioplex3_HEK293     bioplex_WMM     bioplex3_WMM     youn_WMM     bioplex3_HCT116     gupta_WMM     fraction
RNPS1	GPATCH8	0.999	0.376	bioplex3_HEK293     bioplex_WMM     bioplex3_WMM     youn_WMM     hein ()     bioplex3_HCT116     gupta_WMM     fraction
RNPS1	SAP18	0.999		bioplex3_HEK293     bioplex_WMM     Guru     bioplex3_WMM     youn_WMM     bioplex3_HCT116     gupta_WMM     fraction
ACIN1	RNPS1	0.998	0.92	bioplex3_HEK293     bioplex_WMM     bioplex3_WMM     youn_WMM     bioplex3_HCT116     gupta_WMM     fraction
SETD2	SAP18	0.998		bioplex3_HEK293     bioplex_WMM     bioplex3_WMM     youn_WMM     bioplex3_HCT116     WMM_only
RNPS1	SETD2	0.994	0.126	bioplex3_HEK293     bioplex_WMM     bioplex3_WMM     youn_WMM     bioplex3_HCT116     gupta_WMM     WMM_only
GPATCH8	SAP18	0.963		bioplex3_HEK293     bioplex_WMM     bioplex3_WMM     youn_WMM     gupta_WMM     WMM_only
SETD2	GPATCH8	0.929	0.084	bioplex_WMM     bioplex3_WMM     youn_WMM     WMM_only     boldt_WMM
ACIN1	GPATCH8	0.886	0.35	bioplex_WMM     bioplex3_WMM     youn_WMM     gupta_WMM     fraction
ACIN1	SETD2	0.468	0.166	bioplex_WMM     bioplex3_WMM     youn_WMM     fraction





Related Complexes

Genename	Complexes
SAP18	huMAP3_05319.1 huMAP3_05722.1 huMAP3_05740.1 huMAP3_06219.1 huMAP3_07248.1 huMAP3_07561.1 huMAP3_08302.1 huMAP3_08365.1 huMAP3_08467.1 huMAP3_08769.1 huMAP3_09226.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10564.1 huMAP3_10789.1 huMAP3_11073.1
SETD2	huMAP3_02739.1 huMAP3_03484.1 huMAP3_05722.1 huMAP3_08365.1 huMAP3_08769.1 huMAP3_08851.1 huMAP3_09520.1 huMAP3_09637.1 huMAP3_09923.1 huMAP3_11073.1
ACIN1	huMAP3_00373.1 huMAP3_00489.1 huMAP3_02739.1 huMAP3_03253.1 huMAP3_05722.1 huMAP3_06097.1 huMAP3_06219.1 huMAP3_07248.1 huMAP3_08365.1 huMAP3_08745.1 huMAP3_08769.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10250.1 huMAP3_10564.1 huMAP3_11073.1
RNPS1	huMAP3_00373.1 huMAP3_00489.1 huMAP3_02739.1 huMAP3_03253.1 huMAP3_05722.1 huMAP3_06097.1 huMAP3_07248.1 huMAP3_07267.1 huMAP3_07291.1 huMAP3_08365.1 huMAP3_08745.1 huMAP3_08769.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10250.1 huMAP3_10564.1 huMAP3_11073.1
GPATCH8	huMAP3_02739.1 huMAP3_05319.1 huMAP3_05722.1 huMAP3_05740.1 huMAP3_07248.1 huMAP3_07737.1 huMAP3_08302.1 huMAP3_08365.1 huMAP3_08467.1 huMAP3_08769.1 huMAP3_09095.1 huMAP3_09226.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10789.1 huMAP3_11073.1