hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05734.1
Complex Portal: CPX-10844
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FOXRED1 | FAD-dependent oxidoreductase domain-containing protein 1 (EC 1.-.-.-) | 5 | UniProt NCBI |
| PDPR | Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial (PDPr) | 3 | UniProt NCBI |
| PPOX | Protoporphyrinogen oxidase (PPO) (EC 1.3.3.4) | 5 | UniProt NCBI |
| FDXR | NADPH:adrenodoxin oxidoreductase, mitochondrial (AR) (Adrenodoxin reductase) (EC 1.18.1.6) (Ferredoxin--NADP(+) reductase) (Ferredoxin reductase) | 5 | UniProt NCBI |
| NARS2 | Asparaginyl-tRNA synthetase (AsnRS) (NARS2) (EC 6.1.1.22) (Asparagine--tRNA ligase, mitochondrial) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0012103 | 0.0166933934022 | 0.6 | FOXRED1 FDXR NARS2 | Abnormality of the mitochondrion |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| FOXRED1 | PPOX | 0.98 | 0.042 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM treiber_WMM | |
| FOXRED1 | PDPR | 0.979 | 0.026 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PDPR | PPOX | 0.972 | 0.286 | bioplex_WMM bioplex3_WMM WMM_only | |
| PDPR | FDXR | 0.972 | 0.06 | bioplex_WMM bioplex3_WMM WMM_only | |
| PDPR | NARS2 | 0.969 | 0.166 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| FOXRED1 | NARS2 | 0.962 | 0.05 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| FDXR | NARS2 | 0.96 | 0.0766666666667 | bioplex_WMM bioplex3_WMM WMM_only | |
| PPOX | FDXR | 0.952 | 0.1 | bioplex_WMM bioplex3_WMM WMM_only treiber_WMM | |
| PPOX | NARS2 | 0.921 | 0.114 | bioplex_WMM bioplex3_WMM WMM_only | |
| FOXRED1 | FDXR | 0.883 | 0.046 | bioplex_WMM bioplex3_WMM WMM_only treiber_WMM |
Related Complexes