hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05770.1
Complex Portal: CPX-10725
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| VEGFD | Vascular endothelial growth factor D (VEGF-D) (c-Fos-induced growth factor) (FIGF) | 5 | UniProt NCBI |
| UBR4 | E3 ubiquitin-protein ligase UBR4 (EC 2.3.2.27) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (RING-type E3 ubiquitin transferase UBR4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1) | 5 | UniProt NCBI |
| KCMF1 | E3 ubiquitin-protein ligase KCMF1 (EC 2.3.2.27) (FGF-induced in gastric cancer) (Potassium channel modulatory factor) (PCMF) (RING-type E3 ubiquitin transferase KCMF1) (ZZ-type zinc finger-containing protein 1) | 5 | UniProt NCBI |
| ABHD10 | Palmitoyl-protein thioesterase ABHD10, mitochondrial (EC 3.1.2.22) (Acyl-protein thioesterase ABHD10) (Alpha/beta hydrolase domain-containing protein 10) (Abhydrolase domain-containing protein 10) (Mycophenolic acid acyl-glucuronide esterase, mitochondrial) (EC 3.1.1.93) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6780 | 1.53774525569e-05 | 0.5 | UBR4 KCMF1 | RAD6A-KCMF1-UBR4 complex |
| CORUM:5733 | 0.049938562206 | 0.25 | VEGFD | NRP2-VEGFD complex, heparin dependent |
| CORUM:5734 | 0.049938562206 | 0.25 | VEGFD | NRP1-VEGFD complex, heparin dependent |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| UBR4 | KCMF1 | 0.999 | 0.518 | bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM youn_WMM Malo bioplex3_HCT116 fraction | |
| ABHD10 | KCMF1 | 0.999 | 0.038 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| KCMF1 | VEGFD | 0.992 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| ABHD10 | UBR4 | 0.987 | 0.086 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM WMM_only | |
| UBR4 | VEGFD | 0.973 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| ABHD10 | VEGFD | 0.012 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_HCT116 |
Related Complexes
| Genename | Complexes |
|---|---|
| VEGFD | huMAP3_05770.1 huMAP3_11279.1 |
| UBR4 | huMAP3_05284.1 huMAP3_05770.1 huMAP3_06376.1 |
| KCMF1 | huMAP3_05284.1 huMAP3_05770.1 huMAP3_06376.1 huMAP3_11299.1 |
| ABHD10 | huMAP3_00151.1 huMAP3_05284.1 huMAP3_05770.1 huMAP3_06376.1 huMAP3_12178.1 huMAP3_12412.1 |