hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_05787.1

Complex Portal: CPX-12419

Confidence: Very High

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Genename	Protein Name	Uniprot Annotation Score	Links
GGT7	Glutathione hydrolase 7 (EC 3.4.19.13) (Gamma-glutamyltransferase 7) (GGT 7) (EC 2.3.2.2) (Gamma-glutamyltransferase-like 3) (Gamma-glutamyltransferase-like 5) (Gamma-glutamyltranspeptidase 7) [Cleaved into: Glutathione hydrolase 7 heavy chain; Glutathione hydrolase 7 light chain]	5	UniProt NCBI
IRAK1	Interleukin-1 receptor-associated kinase 1 (IRAK-1) (EC 2.7.11.1)	5	UniProt NCBI
NME3	Nucleoside diphosphate kinase 3 (NDK 3) (NDP kinase 3) (EC 2.7.4.6) (DR-nm23) (Nucleoside diphosphate kinase C) (NDPKC) (nm23-H3)	5	UniProt NCBI
TCP11L1	T-complex protein 11-like protein 1	5	UniProt NCBI
TUBA1A	Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]	5	UniProt NCBI
TUBA1C	Tubulin alpha-1C chain (EC 3.6.5.-) (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain]	5	UniProt NCBI
TUBA4A	Tubulin alpha-4A chain (EC 3.6.5.-) (Alpha-tubulin 1) (Testis-specific alpha-tubulin) (Tubulin H2-alpha) (Tubulin alpha-1 chain)	5	UniProt NCBI
TUBB2A	Tubulin beta-2A chain (Tubulin beta class IIa)	5	UniProt NCBI
TUBB4A	Tubulin beta-4A chain (Tubulin 5 beta) (Tubulin beta-4 chain)	5	UniProt NCBI

Showing 1 to 9 of 9 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-190840	4.59338890316e-11	0.555555555556	TUBB2A TUBA1A TUBA1C TUBB4A TUBA4A	Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
REAC:R-HSA-190872	6.23246168802e-11	0.555555555556	TUBB2A TUBA1A TUBA1C TUBB4A TUBA4A	Transport of connexons to the plasma membrane
REAC:R-HSA-389977	1.80189734833e-10	0.555555555556	TUBB2A TUBA1A TUBA1C TUBB4A TUBA4A	Post-chaperonin tubulin folding pathway
REAC:R-HSA-9619483	2.8438017275e-10	0.555555555556	TUBB2A TUBA1A TUBA1C TUBB4A TUBA4A	Activation of AMPK downstream of NMDARs
REAC:R-HSA-389960	2.8438017275e-10	0.555555555556	TUBB2A TUBA1A TUBA1C TUBB4A TUBA4A	Formation of tubulin folding intermediates by CCT/TriC
REAC:R-HSA-389957	4.31912768671e-10	0.555555555556	TUBB2A TUBA1A TUBA1C TUBB4A TUBA4A	Prefoldin mediated transfer of substrate to CCT/TriC
REAC:R-HSA-190861	5.25686745994e-10	0.555555555556	TUBB2A TUBA1A TUBA1C TUBB4A TUBA4A	Gap junction assembly
REAC:R-HSA-5626467	6.35059719407e-10	0.555555555556	TUBB2A TUBA1A TUBA1C TUBB4A TUBA4A	RHO GTPases activate IQGAPs
REAC:R-HSA-9668328	6.35059719407e-10	0.555555555556	TUBB2A TUBA1A TUBA1C TUBB4A TUBA4A	Sealing of the nuclear envelope (NE) by ESCRT-III
REAC:R-HSA-389958	1.07614970976e-09	0.555555555556	TUBB2A TUBA1A TUBA1C TUBB4A TUBA4A	Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding

Showing 1 to 10 of 158 entries

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Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
TUBB2A	TUBA1C	0.996	0.552		hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM treiber_WMM
TUBB2A	TUBB4A	0.996	0.684	structurally_consistent (dimer)	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM treiber_WMM
GGT7	NME3	0.993	0.054		bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only
TUBA1C	TUBB4A	0.993	0.918		bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM fraction boldt_WMM treiber_WMM
TCP11L1	TUBB4A	0.991	0.138		bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM WMM_only
TCP11L1	TUBA1C	0.991	0.382		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM
NME3	TUBA4A	0.988	0.086		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM
TUBB2A	TUBA4A	0.987	0.372		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 fraction boldt_WMM treiber_WMM
TUBA1C	TUBA4A	0.984	0.796		bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM treiber_WMM
TUBB2A	TCP11L1	0.983	0.106	structurally_consistent (dimer)	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM

Showing 1 to 10 of 36 entries

Related Complexes

Genename	Complexes
NME3	huMAP3_04679.1 huMAP3_05787.1 huMAP3_07150.1 huMAP3_08804.1 huMAP3_09258.1 huMAP3_10665.1
IRAK1	huMAP3_01266.1 huMAP3_03377.1 huMAP3_05787.1 huMAP3_09730.1 huMAP3_10023.1 huMAP3_10240.1 huMAP3_10665.1
TUBB2A	huMAP3_00118.1 huMAP3_05787.1 huMAP3_06977.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_14311.1
TUBA1C	huMAP3_03385.1 huMAP3_04456.1 huMAP3_04912.1 huMAP3_05787.1 huMAP3_06977.1 huMAP3_08094.1 huMAP3_08574.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_11156.1
GGT7	huMAP3_03377.1 huMAP3_05787.1 huMAP3_07150.1 huMAP3_07625.1 huMAP3_08262.1 huMAP3_09258.1 huMAP3_09618.1 huMAP3_10023.1 huMAP3_10240.1 huMAP3_10665.1
TUBA4A	huMAP3_05787.1 huMAP3_07625.1 huMAP3_08095.1 huMAP3_08179.1 huMAP3_08262.1 huMAP3_09233.1 huMAP3_09258.1 huMAP3_09618.1 huMAP3_10475.1 huMAP3_10665.1
TUBA1A	huMAP3_02724.1 huMAP3_05787.1 huMAP3_06977.1 huMAP3_07544.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_11156.1
TUBB4A	huMAP3_05787.1 huMAP3_06500.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1
TCP11L1	huMAP3_00374.1 huMAP3_05787.1 huMAP3_06064.1 huMAP3_07544.1 huMAP3_07625.1 huMAP3_07762.1 huMAP3_08179.1 huMAP3_08262.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10547.1 huMAP3_10665.1 huMAP3_11283.1 huMAP3_14236.1