hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05791.1
Complex Portal: CPX-25542
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SUCLA2 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial (EC 6.2.1.5) (ATP-specific succinyl-CoA synthetase subunit beta) (A-SCS) (Succinyl-CoA synthetase beta-A chain) (SCS-betaA) | 5 | UniProt NCBI |
| NUBPL | Iron-sulfur cluster transfer protein NUBPL (IND1 homolog) (Nucleotide-binding protein-like) (huInd1) | 5 | UniProt NCBI |
| AASS | Alpha-aminoadipic semialdehyde synthase, mitochondrial (LKR/SDH) [Includes: Lysine ketoglutarate reductase (LKR) (LOR) (EC 1.5.1.8); Saccharopine dehydrogenase (SDH) (EC 1.5.1.9)] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0025454 | 0.000331922418602 | 1.0 | SUCLA2 AASS NUBPL | Abnormal CSF metabolite concentration |
| HP:0002921 | 0.0208841138977 | 1.0 | SUCLA2 AASS NUBPL | Abnormal cerebrospinal fluid morphology |
| CORUM:394 | 0.0499402709677 | 0.333333333333 | SUCLA2 | Succinyl-CoA synthetase, ADP-forming |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| AASS | SUCLA2 | 0.988 | 0.07 | bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM boldt youn_WMM fraction boldt_WMM | |
| NUBPL | SUCLA2 | 0.957 | 0.192 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | |
| NUBPL | AASS | 0.459 | 0.028 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
Related Complexes