hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05796.1
Complex Portal: CPX-17998
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| INTS8 | Integrator complex subunit 8 (Int8) (Protein kaonashi-1) | 5 | UniProt NCBI |
| HAX1 | HCLS1-associated protein X-1 (HS1-associating protein X-1) (HAX-1) (HS1-binding protein 1) (HSP1BP-1) | 5 | UniProt NCBI |
| SQOR | Sulfide:quinone oxidoreductase, mitochondrial (SQOR) (EC 1.8.5.8) (Sulfide dehydrogenase-like) (Sulfide quinone oxidoreductase) | 5 | UniProt NCBI |
| GCDH | Glutaryl-CoA dehydrogenase, mitochondrial (GCD) (EC 1.3.8.6) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5355 | 0.0092628309276 | 0.5 | SQOR GCDH | Metabolic Epileptic Disorders |
| HPA:0550053 | 0.0399271079825 | 1.0 | INTS8 GCDH HAX1 SQOR | stomach 2; glandular cells[High] |
| CORUM:6292 | 0.049938562206 | 0.25 | HAX1 | HAX-1-XIAP complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| HAX1 | GCDH | 0.99 | 0.04 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 boldt_WMM WMM_only | |
| SQOR | HAX1 | 0.978 | 0.052 | hein_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| INTS8 | HAX1 | 0.956 | 0.012 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SQOR | INTS8 | 0.119 | 0.04 | bioplex3_WMM WMM_only | |
| INTS8 | GCDH | 0.055 | 0.028 | bioplex_WMM bioplex3_WMM WMM_only | |
| SQOR | GCDH | 0.043 | 0.032 | bioplex3_WMM WMM_only |
Related Complexes