hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05801.1
Complex Portal: CPX-24254
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LPCAT4 | Lysophospholipid acyltransferase LPCAT4 (1-acylglycerol-3-phosphate O-acyltransferase 7) (1-AGP acyltransferase 7) (1-AGPAT 7) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n6) (1-alkenylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.121) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acyltransferase-like 3) (Lysophosphatidylcholine acyltransferase 4) (Lysophosphatidylethanolamine acyltransferase 2) (EC 2.3.1.n7) (Plasmalogen synthase) | 5 | UniProt NCBI |
| TFB2M | Dimethyladenosine transferase 2, mitochondrial (EC 2.1.1.-) (Hepatitis C virus NS5A-transactivated protein 5) (HCV NS5A-transactivated protein 5) (Mitochondrial 12S rRNA dimethylase 2) (Mitochondrial transcription factor B2) (h-mtTFB) (h-mtTFB2) (hTFB2M) (mtTFB2) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2) | 5 | UniProt NCBI |
| ACSL1 | Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Acyl-CoA synthetase 1) (ACS1) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 1) (LACS 1) (Long-chain acyl-CoA synthetase 2) (LACS 2) (Long-chain fatty acid-CoA ligase 2) (Palmitoyl-CoA ligase 1) (Palmitoyl-CoA ligase 2) (Phytanate--CoA ligase) (EC 6.2.1.24) | 5 | UniProt NCBI |
| SPG7 | Paraplegin (EC 3.4.24.-) (Cell matrix adhesion regulator) (Spastic paraplegia 7 protein) | 5 | UniProt NCBI |
| ITM2C | Integral membrane protein 2C (Cerebral protein 14) (Transmembrane protein BRI3) [Cleaved into: CT-BRI3] | 5 | UniProt NCBI |
| FASTKD1 | FAST kinase domain-containing protein 1, mitochondrial | 5 | UniProt NCBI |
| PISD | Phosphatidylserine decarboxylase proenzyme, mitochondrial (EC 4.1.1.65) [Cleaved into: Phosphatidylserine decarboxylase beta chain; Phosphatidylserine decarboxylase alpha chain] | 5 | UniProt NCBI |
| KLRC1 | NKG2-A/NKG2-B type II integral membrane protein (CD159 antigen-like family member A) (NK cell receptor A) (NKG2-A/B-activating NK receptor) (CD antigen CD159a) | 5 | UniProt NCBI |
| SLC25A40 | Probable mitochondrial glutathione transporter SLC25A40 (Mitochondrial carrier family protein) (Solute carrier family 25 member 40) | 3 | UniProt NCBI |
| RUSF1 | RUS family member 1 | 5 | UniProt NCBI |
| ATM | Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T mutated) | 5 | UniProt NCBI |
| BDH1 | D-beta-hydroxybutyrate dehydrogenase, mitochondrial (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase) (BDH) (Short chain dehydrogenase/reductase family 9C member 1) | 4 | UniProt NCBI |
| PEX3 | Peroxisomal biogenesis factor 3 (Peroxin-3) (Peroxisomal assembly protein PEX3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5369 | 0.0499436884912 | 0.0833333333333 | ATM | ATM homodimer complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap |
|---|---|---|---|---|
| RUSF1 | ITM2C | 0.996 | 0.038 | |
| LPCAT4 | SPG7 | 0.994 | 0.062 | |
| SLC25A40 | RUSF1 | 0.992 | 0.074 | |
| RUSF1 | TFB2M | 0.992 | 0.022 | |
| BDH1 | RUSF1 | 0.992 | 0.038 | |
| PEX3 | LPCAT4 | 0.992 | 0.04 | |
| LPCAT4 | ACSL1 | 0.991 | 0.086 | |
| RUSF1 | LPCAT4 | 0.991 | 0.056 | |
| BDH1 | LPCAT4 | 0.989 | 0.048 | |
| RUSF1 | FASTKD1 | 0.989 | 0.026 | |
| BDH1 | ITM2C | 0.986 | 0.056 | |
| BDH1 | PISD | 0.986 | 0.016 | |
| PEX3 | RUSF1 | 0.985 | 0.036 | |
| BDH1 | FASTKD1 | 0.984 | 0.038 | |
| PISD | KLRC1 | 0.984 | ||
| FASTKD1 | LPCAT4 | 0.982 | 0.088 | |
| ITM2C | LPCAT4 | 0.979 | 0.156 | |
| ITM2C | ACSL1 | 0.979 | 0.072 | |
| RUSF1 | ACSL1 | 0.978 | 0.034 | |
| BDH1 | ACSL1 | 0.978 | 0.152 | |
| BDH1 | TFB2M | 0.978 | 0.032 | |
| TFB2M | LPCAT4 | 0.978 | 0.098 | |
| TFB2M | FASTKD1 | 0.977 | 0.102 | |
| BDH1 | SLC25A40 | 0.977 | 0.072 | |
| SLC25A40 | ITM2C | 0.977 | 0.044 | |
| ITM2C | TFB2M | 0.977 | 0.05 | |
| BDH1 | PEX3 | 0.976 | 0.05 | |
| PEX3 | FASTKD1 | 0.975 | 0.078 | |
| ITM2C | FASTKD1 | 0.974 | 0.086 | |
| PEX3 | SLC25A40 | 0.974 | 0.054 | |
| ITM2C | PISD | 0.974 | 0.04 | |
| PEX3 | TFB2M | 0.972 | 0.042 | |
| BDH1 | SPG7 | 0.972 | 0.034 | |
| ACSL1 | PISD | 0.971 | 0.036 | |
| RUSF1 | ATM | 0.971 | 0.054 | |
| TFB2M | ACSL1 | 0.971 | 0.066 | |
| RUSF1 | SPG7 | 0.969 | 0.05 | |
| LPCAT4 | PISD | 0.968 | 0.1 | |
| ACSL1 | KLRC1 | 0.967 | ||
| SLC25A40 | ATM | 0.964 | 0.076 | |
| SLC25A40 | ACSL1 | 0.964 | 0.044 | |
| RUSF1 | PISD | 0.963 | 0.012 | |
| PEX3 | ACSL1 | 0.959 | 0.042 | |
| SLC25A40 | LPCAT4 | 0.957 | 0.094 | |
| PEX3 | ITM2C | 0.954 | 0.022 | |
| ACSL1 | SPG7 | 0.951 | 0.082 | |
| SLC25A40 | SPG7 | 0.951 | 0.064 | |
| BDH1 | ATM | 0.951 | 0.172 | |
| SLC25A40 | TFB2M | 0.944 | 0.03 | |
| SLC25A40 | FASTKD1 | 0.944 | 0.08 | |
| TFB2M | SPG7 | 0.943 | 0.012 | |
| FASTKD1 | ACSL1 | 0.942 | 0.078 | |
| TFB2M | ATM | 0.891 | 0.07 | |
| PEX3 | PISD | 0.878 | 0.026 | |
| LPCAT4 | KLRC1 | 0.867 | ||
| FASTKD1 | SPG7 | 0.828 | 0.07 | |
| LPCAT4 | ATM | 0.827 | 0.106 | |
| SLC25A40 | KLRC1 | 0.826 | ||
| FASTKD1 | ATM | 0.814 | 0.114 | |
| PEX3 | SPG7 | 0.81 | 0.04 | |
| SPG7 | PISD | 0.8 | 0.028 | |
| ATM | SPG7 | 0.79 | 0.042 | |
| SLC25A40 | PISD | 0.781 | 0.048 | |
| TFB2M | PISD | 0.754 | 0.026 | |
| FASTKD1 | PISD | 0.749 | 0.082 | |
| RUSF1 | KLRC1 | 0.656 | ||
| TFB2M | KLRC1 | 0.629 | ||
| PEX3 | KLRC1 | 0.606 | ||
| PEX3 | ATM | 0.577 | 0.126 | |
| ATM | ACSL1 | 0.54 | 0.162 | |
| ITM2C | SPG7 | 0.487 | 0.048 | |
| ITM2C | KLRC1 | 0.368 | ||
| BDH1 | KLRC1 | 0.245 | ||
| ITM2C | ATM | 0.233 | 0.105039473684 | |
| ATM | PISD | 0.175 | 0.054 | |
| FASTKD1 | KLRC1 | 0.043 |
Related Complexes