hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_05836.1
Complex Portal: CPX-20559
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KBTBD7 | Kelch repeat and BTB domain-containing protein 7 | 5 | UniProt NCBI |
| LLGL2 | LLGL scribble cell polarity complex component 2 (HGL) (Lethal(2) giant larvae protein homolog 2) | 5 | UniProt NCBI |
| KBTBD8 | Kelch repeat and BTB domain-containing protein 8 (T-cell activation kelch repeat protein) (TA-KRP) | 5 | UniProt NCBI |
| PARD6B | Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B) | 5 | UniProt NCBI |
| CDX1 | Homeobox protein CDX-1 (Caudal-type homeobox protein 1) | 5 | UniProt NCBI |
| GREM2 | Gremlin-2 (Cysteine knot superfamily 1, BMP antagonist 2) (DAN domain family member 3) (Protein related to DAN and cerberus) | 5 | UniProt NCBI |
| RBFA | Putative ribosome-binding factor A, mitochondrial | 5 | UniProt NCBI |
| TEFM | Transcription elongation factor, mitochondrial | 5 | UniProt NCBI |
| KBTBD6 | Kelch repeat and BTB domain-containing protein 6 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:955 | 8.20609246787e-05 | 0.222222222222 | LLGL2 PARD6B | LLGL2-PAR-6B-PRKCI complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PARD6B | LLGL2 | 1.0 | 0.184 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 | |
| KBTBD7 | KBTBD6 | 1.0 | 0.246 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM boldt_WMM |
| KBTBD7 | TEFM | 0.999 | 0.138 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 | |
| KBTBD7 | RBFA | 0.999 | 0.162 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| KBTBD7 | PARD6B | 0.998 | 0.184 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| CDX1 | KBTBD6 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| KBTBD7 | CDX1 | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| KBTBD7 | LLGL2 | 0.993 | 0.092 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| KBTBD7 | GREM2 | 0.992 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| GREM2 | KBTBD6 | 0.984 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| KBTBD7 | KBTBD8 | 0.975 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PARD6B | KBTBD6 | 0.97 | 0.08 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| RBFA | KBTBD6 | 0.963 | 0.11 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| LLGL2 | KBTBD6 | 0.958 | 0.06 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TEFM | RBFA | 0.711 | 0.112 | bioplex_WMM bioplex3_WMM WMM_only | |
| TEFM | PARD6B | 0.64 | 0.058 | bioplex_WMM bioplex3_WMM WMM_only | |
| PARD6B | RBFA | 0.563 | 0.182 | bioplex_WMM bioplex3_WMM WMM_only | |
| TEFM | KBTBD6 | 0.459 | 0.084 | hein_WMM bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| KBTBD8 | TEFM | 0.237 | 0.05 | bioplex_WMM bioplex3_WMM WMM_only | |
| KBTBD8 | RBFA | 0.187 | bioplex_WMM bioplex3_WMM WMM_only | ||
| TEFM | LLGL2 | 0.154 | 0.03 | bioplex3_WMM WMM_only | |
| KBTBD8 | PARD6B | 0.143 | bioplex_WMM bioplex3_WMM WMM_only | ||
| LLGL2 | RBFA | 0.13 | 0.054 | bioplex3_WMM WMM_only | |
| KBTBD8 | KBTBD6 | 0.11 |
mutually_exclusive (Q8WVZ9)
|
bioplex_WMM bioplex3_WMM WMM_only | |
| KBTBD8 | LLGL2 | 0.03 | bioplex3_WMM WMM_only |
Related Complexes