hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_05857.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PCYT1A | Choline-phosphate cytidylyltransferase A (EC 2.7.7.15) (CCT-alpha) (CTP:phosphocholine cytidylyltransferase A) (CCT A) (CT A) (Phosphorylcholine transferase A) | 5 | UniProt NCBI |
| PCYT1B | Choline-phosphate cytidylyltransferase B (EC 2.7.7.15) (CCT-beta) (CTP:phosphocholine cytidylyltransferase B) (CCT B) (CT B) (Phosphorylcholine transferase B) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00440 | 1.62569694473e-06 | 1.0 | PCYT1A PCYT1B | Phosphonate and phosphinate metabolism |
| WP:WP3933 | 3.31996874241e-05 | 1.0 | PCYT1A PCYT1B | Kennedy pathway from sphingolipids |
| WP:WP3940 | 0.000384350227487 | 1.0 | PCYT1A PCYT1B | One carbon metabolism and related pathways |
| REAC:R-HSA-1483191 | 0.000432316723289 | 1.0 | PCYT1A PCYT1B | Synthesis of PC |
| GO:0004105 | 0.000468200720083 | 1.0 | PCYT1A PCYT1B | choline-phosphate cytidylyltransferase activity |
| KEGG:00564 | 0.000500877228672 | 1.0 | PCYT1A PCYT1B | Glycerophospholipid metabolism |
| KEGG:05231 | 0.000553224670293 | 1.0 | PCYT1A PCYT1B | Choline metabolism in cancer |
| WP:WP2525 | 0.000632070972113 | 1.0 | PCYT1A PCYT1B | Trans sulfuration one carbon metabolism and related pathways |
| GO:0006657 | 0.0028092043205 | 1.0 | PCYT1A PCYT1B | CDP-choline pathway |
| REAC:R-HSA-1483206 | 0.00932983916662 | 1.0 | PCYT1A PCYT1B | Glycerophospholipid biosynthesis |
| GO:0070567 | 0.016855225923 | 1.0 | PCYT1A PCYT1B | cytidylyltransferase activity |
| REAC:R-HSA-1483257 | 0.0263149309828 | 1.0 | PCYT1A PCYT1B | Phospholipid metabolism |
| WP:WP528 | 0.0310970405539 | 0.5 | PCYT1A | Acetylcholine synthesis |
| GO:0006656 | 0.0491610756088 | 1.0 | PCYT1A PCYT1B | phosphatidylcholine biosynthetic process |
| HP:0031171 | 0.0499436884913 | 0.5 | PCYT1A | Femoral spur |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PCYT1A | PCYT1B | 0.983 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| PCYT1A | huMAP3_02131.1 huMAP3_02728.1 huMAP3_04069.1 huMAP3_05857.1 |
| PCYT1B | huMAP3_02728.1 huMAP3_04069.1 huMAP3_05857.1 |