hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_05883.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SCO2 | Protein SCO2 homolog, mitochondrial | 5 | UniProt NCBI |
| ZFYVE19 | Abscission/NoCut checkpoint regulator (ANCHR) (MLL partner containing FYVE domain) (Zinc finger FYVE domain-containing protein 19) | 5 | UniProt NCBI |
| VPS4A | Vacuolar protein sorting-associated protein 4A (EC 3.6.4.6) (Protein SKD2) (VPS4-1) (hVPS4) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0044878 | 0.00842684400117 | 0.666666666667 | ZFYVE19 VPS4A | mitotic cytokinesis checkpoint signaling |
| GO:0009838 | 0.0210651876021 | 0.666666666667 | ZFYVE19 VPS4A | abscission |
| GO:0032466 | 0.0210651876021 | 0.666666666667 | ZFYVE19 VPS4A | negative regulation of cytokinesis |
| HP:0002240 | 0.0236211069549 | 1.0 | ZFYVE19 SCO2 VPS4A | Hepatomegaly |
| HP:0003271 | 0.0348981768855 | 1.0 | ZFYVE19 SCO2 VPS4A | Visceromegaly |
| HP:0001438 | 0.0451801948319 | 1.0 | ZFYVE19 SCO2 VPS4A | Abnormal abdomen morphology |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SCO2 | VPS4A | 0.985 | 0.018 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt boldt_WMM |
| ZFYVE19 | VPS4A | 0.982 | 0.174 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| SCO2 | ZFYVE19 | 0.011 | 0.06 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes