hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05889.1
Complex Portal: CPX-22370
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TRIM28 | Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28) | 5 | UniProt NCBI |
| KRBOX5 | KRAB domain-containing protein 5 | 2 | UniProt NCBI |
| ZNF124 | Zinc finger protein 124 (Zinc finger protein HZF-16) | 5 | UniProt NCBI |
| KRBOX4 | KRAB domain-containing protein 4 (KRAB box domain-containing protein 4) | 4 | UniProt NCBI |
| ZNF624 | Zinc finger protein 624 | 4 | UniProt NCBI |
| ZNF674 | Zinc finger protein 674 | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-212436 | 0.00174662531744 | 0.833333333333 | ZNF624 TRIM28 KRBOX5 KRBOX4 ZNF124 | Generic Transcription Pathway |
| REAC:R-HSA-73857 | 0.00300615431734 | 0.833333333333 | ZNF624 TRIM28 KRBOX5 KRBOX4 ZNF124 | RNA Polymerase II Transcription |
| REAC:R-HSA-74160 | 0.00558415609329 | 0.833333333333 | ZNF624 TRIM28 KRBOX5 KRBOX4 ZNF124 | Gene expression (Transcription) |
| KEGG:05168 | 0.0153678589488 | 0.5 | ZNF124 ZNF624 ZNF674 | Herpes simplex virus 1 infection |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ZNF674 | TRIM28 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| KRBOX4 | TRIM28 | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| KRBOX5 | TRIM28 | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| TRIM28 | ZNF124 | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| ZNF624 | TRIM28 | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | ||
| KRBOX5 | ZNF674 | 0.906 | bioplex_WMM bioplex3_WMM WMM_only | ||
| KRBOX5 | KRBOX4 | 0.906 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF674 | ZNF124 | 0.906 | bioplex_WMM bioplex3_WMM WMM_only | ||
| KRBOX5 | ZNF124 | 0.906 | bioplex_WMM bioplex3_WMM WMM_only | ||
| KRBOX4 | ZNF674 | 0.906 | bioplex_WMM bioplex3_WMM WMM_only | ||
| KRBOX4 | ZNF124 | 0.906 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF624 | ZNF124 | 0.741 | bioplex_WMM bioplex3_WMM WMM_only | ||
| KRBOX5 | ZNF624 | 0.741 | bioplex_WMM bioplex3_WMM WMM_only | ||
| KRBOX4 | ZNF624 | 0.73 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF624 | ZNF674 | 0.73 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes