hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_05894.1

Complex Portal: CPX-18741

Confidence: Very High

Genename	Protein Name	Uniprot Annotation Score	Links
ASB3	Ankyrin repeat and SOCS box protein 3 (ASB-3)	5	UniProt NCBI
RAB40AL	Ras-related protein Rab-40A-like (Ras-like GTPase)	4	UniProt NCBI
PCMTD2	Protein-L-isoaspartate O-methyltransferase domain-containing protein 2	5	UniProt NCBI
WSB1	WD repeat and SOCS box-containing protein 1 (WSB-1) (SOCS box-containing WD protein SWiP-1)	5	UniProt NCBI
RAB40C	Ras-related protein Rab-40C (Rar-like protein) (Ras-like protein family member 8C) (SOCS box-containing protein RAR3)	5	UniProt NCBI
ASB9	Ankyrin repeat and SOCS box protein 9 (ASB-9)	5	UniProt NCBI
AMBRA1	Activating molecule in BECN1-regulated autophagy protein 1 (DDB1- and CUL4-associated factor 3)	5	UniProt NCBI
SOCS5	Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2 protein 6) (CIS-6) (Cytokine-inducible SH2-containing protein 5)	5	UniProt NCBI
NEDD8	NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8) (Ubiquitin-like protein Nedd8)	5	UniProt NCBI
TULP4	Tubby-related protein 4 (Tubby superfamily protein) (Tubby-like protein 4)	5	UniProt NCBI
WSB2	WD repeat and SOCS box-containing protein 2 (WSB-2) (CS box-containing WD protein)	3	UniProt NCBI
ELOB	Elongin-B (EloB) (Elongin 18 kDa subunit) (RNA polymerase II transcription factor SIII subunit B) (SIII p18) (Transcription elongation factor B polypeptide 2)	5	UniProt NCBI
ELOC	Elongin-C (EloC) (Elongin 15 kDa subunit) (RNA polymerase II transcription factor SIII subunit C) (SIII p15) (Transcription elongation factor B polypeptide 1)	5	UniProt NCBI
SOCS4	Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7)	5	UniProt NCBI
RNF7	RING-box protein 2 (Rbx2) (CKII beta-binding protein 1) (CKBBP1) (RING finger protein 7) (Regulator of cullins 2) (Sensitive to apoptosis gene protein)	5	UniProt NCBI
SOCS7	Suppressor of cytokine signaling 7 (SOCS-7) (Nck, Ash and phospholipase C gamma-binding protein) (Nck-associated protein 4) (NAP-4)	5	UniProt NCBI
SOCS6	Suppressor of cytokine signaling 6 (SOCS-6) (Cytokine-inducible SH2 protein 4) (CIS-4) (Suppressor of cytokine signaling 4) (SOCS-4)	5	UniProt NCBI
CISH	Cytokine-inducible SH2-containing protein (CIS) (CIS-1) (Protein G18) (Suppressor of cytokine signaling) (SOCS)	5	UniProt NCBI
ISCA1	Iron-sulfur cluster assembly 1 homolog, mitochondrial (HESB-like domain-containing protein 2) (Iron-sulfur assembly protein IscA) (hIscA)	5	UniProt NCBI
SOCS3	Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) (CIS-3) (STAT-induced STAT inhibitor 3) (SSI-3)	5	UniProt NCBI
PCMTD1	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1	5	UniProt NCBI
RAB40A	Ras-related protein Rab-40A (SOCS box-containing protein RAR2A) (Protein Rar-2)	4	UniProt NCBI
SPSB2	SPRY domain-containing SOCS box protein 2 (SSB-2) (Gene-rich cluster protein C9)	5	UniProt NCBI
RAB40B	Ras-related protein Rab-40B (SOCS box-containing protein RAR) (Protein Rar)	4	UniProt NCBI
ARIH2	E3 ubiquitin-protein ligase ARIH2 (ARI-2) (Protein ariadne-2 homolog) (EC 2.3.2.31) (RING-type E3 ubiquitin transferase ARIH2) (Triad1 protein)	5	UniProt NCBI
CUL5	Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-8951664	8.40735427028e-19	0.576923076923	CISH SOCS5 TULP4 WSB1 ASB9 RNF7 CUL5 ASB3 SOCS3 SPSB2 WSB2 ELOC SOCS6 ELOB NEDD8	Neddylation
REAC:R-HSA-597592	1.04382865546e-11	0.692307692308	CISH SOCS5 NEDD8 RNF7 WSB1 RAB40B ASB9 RAB40C CUL5 ASB3 SOCS3 SPSB2 WSB2 ELOC SOCS6 RAB40A ELOB TULP4	Post-translational protein modification
GO:0031466	7.12634361581e-11	0.230769230769	ELOB ARIH2 RNF7 PCMTD1 ELOC CUL5	Cul5-RING ubiquitin ligase complex
CORUM:6268	3.78244070757e-10	0.153846153846	CUL5 ELOC ASB9 ELOB	Cullin-RING E3 ubiquitin ligase complex
CORUM:211	3.78244070757e-10	0.153846153846	CUL5 ELOC ELOB RNF7	Ubiquitin E3 ligase (ASB12, TCEB1, TCEB2, CUL5, RNF7)
CORUM:214	1.88894224289e-09	0.153846153846	CUL5 WSB1 ELOB ELOC	Ubiquitin E3 ligase (WSB1, TCEB1, TCEB2, CUL5, RBX1)
CORUM:210	1.88894224289e-09	0.153846153846	CUL5 ELOC ELOB RNF7	Ubiquitin E3 ligase (ASB7, TCEB1, TCEB2, CUL5, RNF7)
CORUM:209	1.88894224289e-09	0.153846153846	CUL5 ELOC ELOB RNF7	Ubiquitin E3 ligase (ASB6, TCEB1, TCEB2, CUL5, RNF7)
CORUM:208	1.88894224289e-09	0.153846153846	CUL5 ELOC ELOB RNF7	Ubiquitin E3 ligase (ASB1, TCEB1, TCEB2, CUL5, RNF7)
CORUM:207	1.88894224289e-09	0.153846153846	CUL5 ELOC ELOB RNF7	Ubiquitin E3 ligase (ASB2, TCEB1, TCEB2, CUL5, RNF7)
GO:0046935	2.53275250926e-09	0.230769230769	SOCS5 CISH SOCS7 SOCS4 SOCS6 SOCS3	1-phosphatidylinositol-3-kinase regulator activity
REAC:R-HSA-392499	2.94648365157e-09	0.692307692308	CISH SOCS5 NEDD8 RNF7 WSB1 RAB40B ASB9 RAB40C CUL5 ASB3 SOCS3 SPSB2 WSB2 ELOC SOCS6 RAB40A ELOB TULP4	Metabolism of proteins
REAC:R-HSA-983168	7.71353305476e-09	0.384615384615	ELOB ELOC ASB9 RNF7 ARIH2 ASB3 WSB1 SOCS3 CUL5 SPSB2	Antigen processing: Ubiquitination & Proteasome degradation
REAC:R-HSA-983169	5.76038363729e-08	0.384615384615	ELOB ELOC ASB9 RNF7 ARIH2 ASB3 WSB1 SOCS3 CUL5 SPSB2	Class I MHC mediated antigen processing & presentation
KEGG:04917	6.41410127662e-08	0.230769230769	SOCS5 CISH SOCS7 SOCS4 SOCS6 SOCS3	Prolactin signaling pathway
REAC:R-HSA-9705462	1.21907155466e-07	0.192307692308	CUL5 ELOC SOCS3 ELOB RNF7	Inactivation of CSF3 (G-CSF) signaling
GO:0005942	1.47449832462e-07	0.230769230769	SOCS5 CISH SOCS7 SOCS4 SOCS6 SOCS3	phosphatidylinositol 3-kinase complex
GO:1990234	3.41789409406e-07	0.538461538462	CUL5 SOCS5 ELOB ELOC RNF7 ARIH2 SOCS7 SOCS3 SPSB2 PCMTD1 SOCS6 SOCS4 AMBRA1 CISH	transferase complex
REAC:R-HSA-9674555	3.53930792876e-07	0.192307692308	CUL5 ELOC SOCS3 ELOB RNF7	Signaling by CSF3 (G-CSF)
KEGG:04630	6.01175109347e-06	0.230769230769	SOCS5 CISH SOCS7 SOCS4 SOCS6 SOCS3	JAK-STAT signaling pathway
GO:0046854	8.71168005526e-06	0.230769230769	SOCS5 CISH SOCS7 SOCS4 SOCS6 SOCS3	phosphatidylinositol phosphate biosynthetic process
GO:0031461	1.77131004352e-05	0.307692307692	SPSB2 ELOC RNF7 PCMTD1 ARIH2 CUL5 AMBRA1 ELOB	cullin-RING ubiquitin ligase complex
WP:WP3300	2.13374854332e-05	0.115384615385	ELOC ELOB CUL5	Dual hijack model of Vif in HIV infection
REAC:R-HSA-1280218	3.00206477761e-05	0.384615384615	ELOB ELOC ASB9 RNF7 ARIH2 ASB3 WSB1 SOCS3 CUL5 SPSB2	Adaptive Immune System
GO:0032446	9.08040433826e-05	0.423076923077	NEDD8 ELOC ASB9 AMBRA1 ARIH2 RNF7 PCMTD1 WSB1 CUL5 WSB2 SPSB2	protein modification by small protein conjugation
CORUM:6738	0.000146312725026	0.0769230769231	ELOC ELOB	PRAME-ElonginBC ubiquitin ligase
KEGG:04120	0.000229952391836	0.192307692308	CUL5 ELOC SOCS3 ELOB RNF7	Ubiquitin mediated proteolysis
GO:0070647	0.000255666134936	0.423076923077	NEDD8 ELOC ASB9 AMBRA1 ARIH2 RNF7 PCMTD1 WSB1 CUL5 WSB2 SPSB2	protein modification by small protein conjugation or removal
WP:WP5072	0.000266133920922	0.153846153846	CUL5 ARIH2 ELOB RNF7	Modulators of TCR signaling and T cell activation
CORUM:7576	0.000438457574873	0.0769230769231	ELOC ELOB	VHL-ElonginB-ElonginC complex
CORUM:5270	0.000438457574873	0.0769230769231	ELOC ELOB	VHL-TCEB1-TCEB2 complex
GO:0016567	0.000448711616789	0.384615384615	SPSB2 WSB1 ASB9 RNF7 ARIH2 PCMTD1 WSB2 CUL5 ELOC AMBRA1	protein ubiquitination
REAC:R-HSA-168256	0.000468894614721	0.5	SOCS5 ELOB ELOC ASB9 RNF7 ARIH2 ASB3 SOCS3 SPSB2 WSB1 SOCS6 CUL5 CISH	Immune System
GO:0043687	0.00050666045086	0.423076923077	NEDD8 ELOC ASB9 AMBRA1 ARIH2 RNF7 PCMTD1 WSB1 CUL5 WSB2 SPSB2	post-translational protein modification
CORUM:5267	0.000875955084067	0.0769230769231	ELOC ELOB	VHL-VDU1-TCEB1-TCEB2 complex
CORUM:6485	0.000875955084067	0.0769230769231	ELOC ELOB	HIF1alpha-VHL-ElonginB-ElonginC complex
CORUM:622	0.000875955084067	0.0769230769231	ELOC ELOB	Ubiquitin E3 ligase (VHL, TCEB1, TCEB2, CUL2)
GO:0000151	0.000899591207012	0.307692307692	SPSB2 ELOC RNF7 PCMTD1 ARIH2 CUL5 AMBRA1 ELOB	ubiquitin ligase complex
GO:0006661	0.00136628665459	0.230769230769	SOCS5 CISH SOCS7 SOCS4 SOCS6 SOCS3	phosphatidylinositol biosynthetic process
GO:0030163	0.00141095767205	0.423076923077	SOCS5 ELOB ELOC ASB9 RNF7 CUL5 SPSB2 ARIH2 SOCS6 AMBRA1 NEDD8	protein catabolic process
CORUM:205	0.00145832691959	0.0769230769231	ELOC ELOB	Ubiquitin E3 ligase (VHL, TCEB1, TCEB2, CUL2, RBX1)
GO:0051603	0.00196852404719	0.384615384615	SOCS5 ELOB ELOC RNF7 CUL5 SPSB2 ARIH2 SOCS6 AMBRA1 NEDD8	proteolysis involved in protein catabolic process
REAC:R-HSA-1280215	0.00217650397763	0.307692307692	SOCS5 CISH ELOC RNF7 CUL5 SOCS3 SOCS6 ELOB	Cytokine Signaling in Immune system
CORUM:7556	0.0021850958786	0.0769230769231	ELOC ELOB	PRAME complex
GO:1902494	0.00252356667208	0.538461538462	CUL5 SOCS5 ELOB ELOC RNF7 ARIH2 SOCS7 SOCS3 SPSB2 PCMTD1 SOCS6 SOCS4 AMBRA1 CISH	catalytic complex
GO:0046488	0.0034716950226	0.230769230769	SOCS5 CISH SOCS7 SOCS4 SOCS6 SOCS3	phosphatidylinositol metabolic process
GO:0006511	0.00475560727773	0.346153846154	SOCS5 ELOB ELOC RNF7 SPSB2 ARIH2 CUL5 AMBRA1 NEDD8	ubiquitin-dependent protein catabolic process
GO:0019941	0.00545959192527	0.346153846154	SOCS5 ELOB ELOC RNF7 SPSB2 ARIH2 CUL5 AMBRA1 NEDD8	modification-dependent protein catabolic process
GO:0043632	0.00657557873027	0.346153846154	SOCS5 ELOB ELOC RNF7 SPSB2 ARIH2 CUL5 AMBRA1 NEDD8	modification-dependent macromolecule catabolic process
GO:0019898	0.00711678635084	0.230769230769	SOCS5 CISH SOCS7 SOCS4 SOCS6 SOCS3	extrinsic component of membrane
WP:WP2864	0.00772900330201	0.115384615385	SOCS3 RNF7 CUL5	Apoptosis related network due to altered Notch3 in ovarian cancer
WP:WP4860	0.0103743109626	0.0769230769231	ELOC ELOB	Hijack of ubiquitination by SARS CoV 2
GO:0046474	0.0193781387755	0.230769230769	SOCS5 CISH SOCS7 SOCS4 SOCS6 SOCS3	glycerophospholipid biosynthetic process
KEGG:05170	0.0229701083449	0.153846153846	CUL5 ELOC ELOB RNF7	Human immunodeficiency virus 1 infection
REAC:R-HSA-8939242	0.0264544929546	0.0769230769231	SOCS4 SOCS3	RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
WP:WP2034	0.028430521029	0.115384615385	SOCS7 CISH SOCS3	Leptin signaling pathway
REAC:R-HSA-180585	0.0325789654876	0.115384615385	ELOC ELOB CUL5	Vif-mediated degradation of APOBEC3G
GO:0009057	0.0349932534908	0.423076923077	SOCS5 ELOB ELOC ASB9 RNF7 CUL5 SPSB2 ARIH2 SOCS6 AMBRA1 NEDD8	macromolecule catabolic process
GO:1901565	0.037755291375	0.423076923077	SOCS5 ELOB ELOC ASB9 RNF7 CUL5 SPSB2 ARIH2 SOCS6 AMBRA1 NEDD8	organonitrogen compound catabolic process
GO:0008654	0.0413578599545	0.230769230769	SOCS5 CISH SOCS7 SOCS4 SOCS6 SOCS3	phospholipid biosynthetic process

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
RAB40C	RAB40B	1.0		mutually_exclusive (Q15369)
RAB40AL	RAB40A	1.0
ASB3	CUL5	1.0	0.044
ELOC	RAB40B	1.0		structurally_consistent (dimer)
CISH	CUL5	1.0
RNF7	CUL5	1.0	0.544	structurally_consistent (dimer)
ELOB	ELOC	1.0	0.944	mixed_interface
SOCS6	CUL5	1.0	0.228
SPSB2	CUL5	0.999		structurally_consistent (O95376)
RAB40C	CUL5	0.999	0.076
ARIH2	CUL5	0.999	0.036	structurally_consistent (dimer)
ELOC	RAB40C	0.999	0.12	structurally_consistent (dimer)
ISCA1	RAB40A	0.999
RAB40B	CUL5	0.999
RAB40AL	CUL5	0.999
TULP4	CUL5	0.999
WSB2	CUL5	0.999
ELOB	SOCS6	0.999	0.147378787879
ELOB	RAB40C	0.999	0.142	mutually_exclusive (Q15369)
SOCS7	CUL5	0.998
SOCS5	CUL5	0.998		mutually_exclusive (Q15369)
ELOB	SPSB2	0.998		mixed_interface
ELOB	RAB40B	0.998		mutually_exclusive (Q15369)
ELOB	CISH	0.998
RAB40A	ARIH2	0.998
RAB40C	RNF7	0.997	0.088
WSB1	CUL5	0.997
SOCS4	CUL5	0.997		structurally_consistent (dimer)
SPSB2	RNF7	0.997		structurally_consistent (O95376)
NEDD8	CUL5	0.997	0.066
SOCS5	RNF7	0.997
WSB1	RNF7	0.997
RNF7	SOCS6	0.997	0.102
SOCS4	RNF7	0.997		structurally_consistent (Q93034)
ASB9	ELOC	0.997	0.19	structurally_consistent (dimer)
RNF7	RAB40B	0.997
ASB3	RNF7	0.996	0.112
ELOC	SOCS6	0.996	0.172	structurally_consistent (O14508)
ELOC	CISH	0.996
ELOC	RAB40AL	0.996
ASB9	ELOB	0.995	0.134
ELOC	CUL5	0.995	0.226	structurally_consistent (dimer)
SOCS7	RNF7	0.995
SPSB2	NEDD8	0.995
ELOC	RNF7	0.995	0.162
ASB9	CUL5	0.995	0.072	structurally_consistent (O95376)
ELOB	RNF7	0.995	0.332
SOCS6	ARIH2	0.995	0.172
WSB2	RNF7	0.995
ISCA1	RAB40C	0.994	0.046
ELOC	ARIH2	0.994	0.336
ELOB	ARIH2	0.994	0.314
ASB3	ELOC	0.993	0.19	structurally_consistent (dimer)
ELOC	SPSB2	0.992		mixed_interface
ELOC	AMBRA1	0.992	0.21
ELOB	RAB40A	0.991		mutually_exclusive (Q15369)
RNF7	CISH	0.991
PCMTD1	CUL5	0.991	0.034
RAB40A	CUL5	0.991
RNF7	PCMTD1	0.99	0.082
ASB3	ELOB	0.987	0.2	mutually_exclusive (Q15369)
AMBRA1	SOCS3	0.986
AMBRA1	WSB2	0.982
ELOB	RAB40AL	0.982
ELOC	RAB40A	0.981		structurally_consistent (dimer)
PCMTD2	RNF7	0.98	0.128
ASB9	RNF7	0.98	0.066	structurally_consistent (O95376)
ISCA1	CUL5	0.98	0.022
ISCA1	RAB40B	0.98
RAB40B	ARIH2	0.979
NEDD8	SOCS6	0.979	0.196
NEDD8	RAB40A	0.978
RNF7	ARIH2	0.978	0.166	structurally_consistent (dimer)
PCMTD2	CUL5	0.976	0.06
ELOB	SOCS3	0.976		mutually_exclusive (Q15369)
TULP4	RNF7	0.974
ELOC	SOCS3	0.974		structurally_consistent (dimer)
AMBRA1	CUL5	0.972	0.078
NEDD8	RNF7	0.971	0.31
RAB40C	ARIH2	0.969	0.104
ELOB	CUL5	0.968	0.248
ELOC	SOCS7	0.968
ELOC	WSB2	0.967
NEDD8	CISH	0.963
ELOC	NEDD8	0.962	0.458
ASB9	NEDD8	0.957	0.124
SPSB2	ARIH2	0.956		structurally_consistent (dimer)
ELOB	AMBRA1	0.952	0.208
ELOB	SOCS7	0.945
ELOB	WSB2	0.944
PCMTD2	PCMTD1	0.941	0.136
ISCA1	RAB40AL	0.94
SOCS5	SOCS6	0.925
SOCS4	SOCS6	0.925
WSB1	SOCS6	0.925
ASB3	RAB40C	0.917	0.066	mutually_exclusive (Q15369)
ISCA1	ELOC	0.915	0.14
WSB1	SOCS4	0.913		mutually_exclusive (Q15369)
SOCS7	SOCS5	0.913
SOCS7	SOCS4	0.913
SOCS5	SOCS4	0.913		mutually_exclusive (Q15369)
WSB1	SOCS5	0.913		mutually_exclusive (Q15369)
SOCS7	WSB1	0.913
WSB1	CISH	0.907
SOCS4	CISH	0.907
SOCS5	CISH	0.907
RAB40AL	ARIH2	0.905
RAB40AL	RAB40B	0.88
ELOB	TULP4	0.878
ASB9	ARIH2	0.866	0.116	structurally_consistent (dimer)
RAB40AL	RAB40C	0.863
SPSB2	SOCS5	0.861		mutually_exclusive (Q15369)
SPSB2	SOCS4	0.861		mutually_exclusive (Q15369)
SPSB2	WSB1	0.861		mutually_exclusive (Q15369)
SOCS7	SOCS6	0.861
ELOC	TULP4	0.854
ELOB	NEDD8	0.852	0.48
WSB1	RAB40C	0.852		mutually_exclusive (Q15369)
SOCS4	RAB40B	0.852		mutually_exclusive (Q15369)
RAB40C	SOCS4	0.852		mutually_exclusive (Q15369)
WSB2	SOCS4	0.852
WSB2	WSB1	0.852
RAB40C	SOCS5	0.852		mutually_exclusive (Q15369)
SOCS5	RAB40B	0.852		mutually_exclusive (Q15369)
WSB1	RAB40B	0.852		mutually_exclusive (Q15369)
WSB2	SOCS5	0.852
AMBRA1	RAB40C	0.849	0.08
ISCA1	ELOB	0.846	0.08
SOCS7	CISH	0.83
SOCS7	SPSB2	0.823
SOCS5	TULP4	0.821
WSB1	TULP4	0.821
TULP4	SOCS4	0.821
RAB40C	SOCS6	0.812	0.044
SPSB2	SOCS6	0.812
SOCS7	RAB40C	0.812
ASB3	WSB1	0.812		mutually_exclusive (Q15369)
ASB3	SOCS4	0.812		mutually_exclusive (Q15369)
SOCS7	RAB40B	0.812
SOCS7	WSB2	0.812
SOCS6	RAB40B	0.812
ASB3	SOCS5	0.812		mutually_exclusive (Q15369)
WSB2	SOCS6	0.812
SOCS7	PCMTD1	0.795
SOCS3	CUL5	0.794
SOCS6	CISH	0.787
TULP4	SOCS6	0.786
PCMTD2	SOCS4	0.785
PCMTD2	WSB1	0.785
PCMTD2	SOCS5	0.785
ASB3	PCMTD2	0.784	0.142
ASB3	SOCS7	0.783
SOCS4	PCMTD1	0.778
WSB1	PCMTD1	0.778
SOCS5	PCMTD1	0.778
ASB3	RAB40B	0.778		mutually_exclusive (Q15369)
ASB3	WSB2	0.778
ASB3	SOCS6	0.778	0.136
ASB3	SPSB2	0.778		mutually_exclusive (Q15369)
SOCS7	TULP4	0.775
SPSB2	WSB2	0.765
SPSB2	RAB40C	0.759		mutually_exclusive (Q15369)
SPSB2	RAB40B	0.759		mutually_exclusive (Q15369)
ASB3	TULP4	0.754
RAB40C	TULP4	0.754
SOCS6	PCMTD1	0.751	0.056
WSB2	RAB40B	0.75
WSB2	RAB40C	0.75
NEDD8	RAB40B	0.739
WSB2	TULP4	0.735
SPSB2	TULP4	0.735
TULP4	RAB40B	0.735
NEDD8	ARIH2	0.72	0.108
ASB3	PCMTD1	0.719	0.108
SOCS7	PCMTD2	0.714
AMBRA1	ARIH2	0.708	0.142
AMBRA1	CISH	0.706
RAB40C	PCMTD1	0.697	0.038
AMBRA1	SPSB2	0.689
ISCA1	ARIH2	0.688	0.082
PCMTD2	TULP4	0.685
SPSB2	CISH	0.683
RAB40C	CISH	0.676
WSB2	CISH	0.676
CISH	RAB40B	0.676
SPSB2	PCMTD1	0.671
WSB2	PCMTD1	0.671
TULP4	ARIH2	0.665
AMBRA1	RNF7	0.637	0.09
ASB3	CISH	0.633
AMBRA1	SOCS6	0.612	0.12
AMBRA1	RAB40B	0.608
PCMTD1	RAB40B	0.606
SOCS5	ARIH2	0.603
WSB1	ARIH2	0.603
SOCS4	ARIH2	0.603
SOCS7	ARIH2	0.603
NEDD8	SOCS4	0.554
WSB1	NEDD8	0.554
SOCS7	NEDD8	0.554
SOCS5	NEDD8	0.554
RAB40C	NEDD8	0.553	0.1
WSB2	NEDD8	0.536
TULP4	PCMTD1	0.512
WSB2	ARIH2	0.508
AMBRA1	RAB40A	0.49
CISH	PCMTD1	0.459
SPSB2	PCMTD2	0.451
ISCA1	AMBRA1	0.442	0.118
NEDD8	TULP4	0.438
ASB3	NEDD8	0.436	0.182
PCMTD2	RAB40B	0.428
PCMTD2	RAB40C	0.351	0.086
PCMTD2	SOCS6	0.334	0.044
WSB2	PCMTD2	0.316
ELOB	SOCS4	0.288
ELOB	SOCS5	0.288		mutually_exclusive (Q15369)
ELOB	WSB1	0.288		mutually_exclusive (Q15369)
ELOC	SOCS5	0.287		structurally_consistent (dimer)
ELOC	SOCS4	0.287		structurally_consistent (Q93034) structurally_consistent (dimer)
ELOC	WSB1	0.287		structurally_consistent (dimer)
RAB40AL	NEDD8	0.266
TULP4	CISH	0.265
AMBRA1	RAB40AL	0.264
ASB3	ARIH2	0.228	0.094
PCMTD1	ARIH2	0.224	0.058
ISCA1	RNF7	0.173	0.086
ELOC	PCMTD1	0.17	0.126
CISH	ARIH2	0.143
PCMTD2	CISH	0.133
ELOB	PCMTD1	0.128	0.046
PCMTD2	NEDD8	0.111	0.118
ASB3	AMBRA1	0.102	0.078
ELOC	PCMTD2	0.087	0.138
NEDD8	PCMTD1	0.075	0.058
AMBRA1	NEDD8	0.07	0.096
RAB40AL	RNF7	0.046
ISCA1	NEDD8	0.041	0.024
ELOB	PCMTD2	0.032	0.182
PCMTD2	ARIH2	0.03	0.092
SOCS3	NEDD8	0.029
AMBRA1	TULP4	0.023
AMBRA1	SOCS7	0.015
PCMTD1	RAB40A	0.007
SOCS3	PCMTD1	0.007
AMBRA1	PCMTD1	0.005	0.076
ISCA1	PCMTD2	0.003	0.086
SOCS3	PCMTD2	0.003
PCMTD2	RAB40A	0.002
AMBRA1	PCMTD2	0.001	0.098

Related Complexes

Genename	Complexes
ASB3	huMAP3_02523.1 huMAP3_04750.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_11029.1 huMAP3_11858.1 huMAP3_13601.1
RAB40AL	huMAP3_04750.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_13601.1 huMAP3_14374.1 huMAP3_14380.1
PCMTD2	huMAP3_04750.1 huMAP3_05263.1 huMAP3_05894.1 huMAP3_06706.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_10502.1 huMAP3_13601.1 huMAP3_14346.1
WSB1	huMAP3_04750.1 huMAP3_05263.1 huMAP3_05894.1 huMAP3_06706.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_10502.1 huMAP3_13601.1
RAB40C	huMAP3_04750.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_13601.1
ASB9	huMAP3_00709.1 huMAP3_04750.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_12854.1
AMBRA1	huMAP3_03188.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09357.1 huMAP3_09980.1 huMAP3_10637.1
SOCS5	huMAP3_04750.1 huMAP3_05263.1 huMAP3_05894.1 huMAP3_06706.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_10502.1 huMAP3_13601.1
NEDD8	huMAP3_04750.1 huMAP3_05041.1 huMAP3_05816.1 huMAP3_05894.1 huMAP3_08550.1 huMAP3_08919.1 huMAP3_09779.1 huMAP3_09980.1 huMAP3_14528.1
TULP4	huMAP3_04750.1 huMAP3_05263.1 huMAP3_05894.1 huMAP3_06706.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_10502.1 huMAP3_13601.1
WSB2	huMAP3_03772.1 huMAP3_04072.1 huMAP3_04750.1 huMAP3_05894.1 huMAP3_06819.1 huMAP3_08860.1 huMAP3_08919.1 huMAP3_09036.1 huMAP3_09980.1 huMAP3_10139.1 huMAP3_10942.1 huMAP3_11361.1 huMAP3_13601.1 huMAP3_14626.1
ELOB	huMAP3_03188.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_13601.1
ELOC	huMAP3_03188.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_13601.1
SOCS4	huMAP3_04750.1 huMAP3_05263.1 huMAP3_05894.1 huMAP3_06706.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_10502.1 huMAP3_13601.1
RNF7	huMAP3_04750.1 huMAP3_05263.1 huMAP3_05894.1 huMAP3_06706.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_10502.1 huMAP3_13601.1
SOCS7	huMAP3_03653.1 huMAP3_04750.1 huMAP3_05894.1 huMAP3_06706.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_10502.1 huMAP3_13601.1
SOCS6	huMAP3_04750.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_13601.1
CISH	huMAP3_04750.1 huMAP3_05263.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_10502.1 huMAP3_13601.1
ISCA1	huMAP3_02435.1 huMAP3_04463.1 huMAP3_04613.1 huMAP3_05894.1 huMAP3_08903.1 huMAP3_09980.1 huMAP3_10741.1 huMAP3_13601.1 huMAP3_14176.1
SOCS3	huMAP3_03188.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09357.1 huMAP3_09980.1 huMAP3_10488.1 huMAP3_12329.1
PCMTD1	huMAP3_04750.1 huMAP3_05263.1 huMAP3_05894.1 huMAP3_06706.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_10502.1 huMAP3_13601.1 huMAP3_14346.1
RAB40A	huMAP3_04750.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_13601.1 huMAP3_14380.1
SPSB2	huMAP3_03667.1 huMAP3_04750.1 huMAP3_05768.1 huMAP3_05894.1 huMAP3_06119.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_11027.1 huMAP3_11202.1 huMAP3_13601.1 huMAP3_13839.1
RAB40B	huMAP3_04750.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_13601.1
ARIH2	huMAP3_04750.1 huMAP3_05894.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_13601.1 huMAP3_14380.1
CUL5	huMAP3_04750.1 huMAP3_05263.1 huMAP3_05894.1 huMAP3_06706.1 huMAP3_08919.1 huMAP3_09980.1 huMAP3_10502.1 huMAP3_13601.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_05894.1

Complex Portal: CPX-18741