hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_05904.1
Complex Portal: CPX-21620
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CTSB | Cathepsin B (EC 3.4.22.1) (APP secretase) (APPS) (Cathepsin B1) [Cleaved into: Cathepsin B light chain; Cathepsin B heavy chain] | 5 | UniProt NCBI |
| CST3 | Cystatin-C (Cystatin-3) (Gamma-trace) (Neuroendocrine basic polypeptide) (Post-gamma-globulin) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0271143 | 0.019796826334 | 1.0 | CST3 CTSB | kidney; proximal tubules (cell body)[High] |
| WP:WP3890 | 0.0310970405539 | 0.5 | CTSB | Nanomaterial induced inflammasome activation |
| HPA:0461451 | 0.0357108364136 | 1.0 | CST3 CTSB | skin 1; hair follicles[>=Low] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CTSB | CST3 | 0.994 | 0.330580645161 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction |
Related Complexes
| Genename | Complexes |
|---|---|
| CTSB | huMAP3_01937.1 huMAP3_05904.1 huMAP3_10735.1 huMAP3_10846.1 |
| CST3 | huMAP3_01937.1 huMAP3_05904.1 huMAP3_06810.1 huMAP3_10735.1 huMAP3_10846.1 huMAP3_11662.1 huMAP3_14085.1 |