hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05914.1
Complex Portal: CPX-21616
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ERI1 | 3'-5' exoribonuclease 1 (EC 3.1.-.-) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3'-end-specific exoribonuclease) (Histone mRNA 3'-exonuclease 1) (Protein 3'hExo) (HEXO) | 5 | UniProt NCBI |
| NEIL1 | Endonuclease 8-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (Endonuclease VIII-like 1) (FPG1) (Nei homolog 1) (NEH1) (Nei-like protein 1) | 5 | UniProt NCBI |
| DUSP6 | Dual specificity protein phosphatase 6 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase PYST1) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2805 | 0.0496447587094 | 0.333333333333 | ERI1 | exRNA mechanism of action and biogenesis |
| REAC:R-HSA-9616334 | 0.0498224659464 | 0.333333333333 | NEIL1 | Defective Base Excision Repair Associated with NEIL1 |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| NEIL1 | DUSP6 | 0.995 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| NEIL1 | ERI1 | 0.99 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes